Routine Services

Mass Spectrometry

MALDI- TOF
  • molecular weight analysis
  • peptide fingerprint analysis
  TOF/TOF
  • MS/MS identification of pure proteins
  • proteins in gel slices or solution
LC-MALDI- TOF/TOF
  • identification of low complexity protein mixtures
  • identification of proteins in complexes
LC-ESI-MS/MS LTQ
  • high coverage MS/MS analysis
  • phosphorylation analysis
  • protein identifications present at low concentrations
  • identification of proteins in complex mixtures
  LCQ
  • high coverage MS/MS analysis (lower cost than LTQ)

Protein Separation

PF2D
  • disease biomarker analysis, via 2-D LC/LC separation
PPS
  • affinity depletion of abundant serum proteins
Custom Separation
  • numerous methods to pre-treat samples prior to MS analysis
  • phosphopeptide enrichment on titanium dioxide resin
1-D and 2-D gel anaysis
  • comparative analysis of protein samples, followed by MS
SELDI
  • biomarker screening analysis
  • MW spectrum analysis of different samples/mutants