Staff

Directors

Alan Friedman, Ph.D., DirectorAlan Friedman, Ph.D., Director

Collaborative Research. Alan Friedman collaborates with individual investigators to develop novel applications and bring new technological capabilities to the scientific community, serving the advanced mass spectrometry needs of the Center's customer base. See Alan's faculty page for his independent research projects.

Fred Hagen, Ph.D., Technical DirectorFred Hagen, Ph.D., Technical Director

Routine Core Services. Fred Hagen oversees the routine operation of the Proteomics Center. He coordinates the application of proteomic technologies for core users and advises users on successful experimental design for implementing protein purification/preparation techniques with mass spectrometry.

Technical Staff

 

Kevin WelleKevin Welle,
B.S. in Mathematics, SUNY Geneseo

Katie MarshallKatie Marshall, B.A. in Psychology with a minor in Biology, SUNY Geneseo

The Center's staff is trained on all technologies offered for routine sample analysis. Separation capabilities include 1- and 2-dimensional gel electrophoresis with multiple imaging formats, as well as 1- and 2-dimensional HPLC. Mass spectrometry systems include MALDI-TOF/TOF, using the AutoFlex III smartbeam instrument (Bruker Daltonics), and LC-MS/MS, using the LTQ linear ion trap instrument (Thermo Scientific). High throughput analyses can be performed using the LC-MS/MS system for electrospray ionization or the integration of HPLC separations with a robot plate spotter (Bruker Proteineer fc) for conducting automated runs on the MALDI-TOF/TOF instrument. Data processing occurs primarily using THERMO Sequest SOFTWARE or MASCOT database searches for analysis of mass spectrometry results.