The Foster Research Group
Our Publications
[2008] [2007] [2006] [2005] [2004] [2003] [2002] [2001] [2000] [1999] [1998] [1997] [1996] [1995] [1994] [1993] [1992] [1991]
2008
R.J. Cummings, S. Mitra, E.M. Lord, and T.H. Foster. Antibody-labeled fluorescence imaging of dendritic cell populations in vivo. J. Biomed. Opt. In press (2008).
K.K.-H. Wang, S. Mitra, and T.H. Foster. Photodynamic dose does not correlate with long-term tumor response to mTHPC-PDT performed at several drug-light intervals. Med. Phys. In press (2008).
T.K. Lee, E.D. Baron, and T.H. Foster. Monitoring Pc 4-PDT in clinical trials of cutaneous T-cell lymphoma using noninvasive spectroscopy. J. Biomed. Opt. 13, 030507 (2008).
W.J. Cottrell, A.D. Paquette, K.R. Keymel, T.H. Foster, and A.R. Oseroff. Irradiance-dependent photobleaching and pain in delta-aminolevulinic acid-photodynamic therapy of superficial basal cell carcinomas. Clin. Cancer Res. In press (2008).
M. Seshadri, D.A. Bellnier, L.A. Vaughan, J.A. Spernyak, R. Mazurchuk, T.H. Foster, and B.W. Henderson. Light delivery over extended time periods enhances the effectiveness of photodynamic therapy. Clin. Cancer Res. 14, 2796-2805 (2008). [Medline]
S. Mitra and T.H. Foster. In vivo confocal fluorescence imaging of the intratumor distribution of the photosensitizer mono-L-aspartylchlorin-e6 (NPe6). Neoplasia 10, 429-438 (2008). [Medline]
Y. Chabrier-Rosello, T.H. Foster, S. Mitra, and C.G. Haidaris. Respiratory deficiency enhances the sensitivity of the pathogenic fungus Candida to photodynamic treatment. Photochem. Photobiol. In press (2007). [Medline]
2007
J.H. Won, W.J. Cottrell, T.H. Foster, and D.I. Yule. Ca2+ release dynamics in parotid and pancreatic exocrine acinar cells evoked by spatially limited flash photolysis. Am. J. Physiol. Gastrointest. Liver Physiol. 293, G1166-G1177 (2007). [Medline]
J.D. Wilson, B.R. Giesselman, S. Mitra, and T.H. Foster. Lysosome-damage-induced scattering changes coincide with release of cytochrome c. Opt. Lett. 32, 2517-2519 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-17-2517.
W.J. Cottrell, J.D. Wilson, and T.H. Foster. Microscope enabling multi-modality imaging, angle-resolved scattering and scattering spectroscopy. Opt. Lett. 32, 2348-2350 (2007). http://www.opticsinfobase.org/abstract.cfm?URI=ol-32-16-2348.
J.D. Wilson and T.H. Foster. Characterization of lysosomal contribution to whole-cell light scattering as quantified by photodynamic organelle ablation. J. Biomed. Opt. 12, 030503 (2007). [PDF]
K. K-H Wang, J.D. Wilson, M.E. Kenney, S. Mitra, and T.H. Foster. Irradiation-induced enhancement of Pc 4 fluorescence and changes in light scattering are potential dosimeters for Pc 4-PDT. Photochem. Photobiol. 83, 1056-1062 (2007). [Medline]
K. Santos, D.A.L. Simon, E. Conway, W.J. Bowers, S. Mitra, T.H. Foster, A. Lugade, E.M. Lord, H.J. Federoff, S. Dewhurst, and J.G. Frelinger. Spatial and temporal expression of herpes simplex virus type 1 amplicon-encoded genes: implications for their use as immunization vectors. Hum. Gene Ther. 18, 93-105 (2007). [Medline]
J.D. Wilson, W.J. Cottrell, and T.H. Foster. Index of refraction-dependent sub-cellular light scattering observed with organelle specific dyes. J. Biomed. Opt. 12, 014010 (2007). [PDF]
K. K-H Wang, S. Mitra, and T.H. Foster. A comprehensive mathematical model of microscopic dose deposition in photodynamic therapy. Med. Phys. 34, 282-293 (2007).
2006
S. Mitra, S.E. Cassar, D.J. Niles, J.A. Puskas, J.G. Frelinger, and T.H. Foster. Photodynamic therapy mediates the oxygen-independent activation of hypoxia-inducible factor-1alpha. Mol. Cancer Ther. 5, 3268-3274 (2006). [Medline]
S.A. Gerber, V.Y. Rybalko, C.E. Bigelow, A.A. Lugade, T.H. Foster, J.G. Frelinger, and E.M. Lord. Preferential attachment of peritoneal tumor metastases to omental immune aggregates and possible role of a unique vascular microenvironment in metastatic survival and growth. Am. J. Pathol. 169, 1739-1752 (2006).
C.E. Bigelow and T.H. Foster. Confocal fluorescence polarization microscopy in turbid media: Effects of scattering-induced depolarization. J. Opt. Soc. Am. A. 23, 2932-2943 (2006).
W.J. Cottrell, A.R. Oseroff, and T.H. Foster. A portable instrument that integrates irradiation with fluorescence and reflectance spectroscopies during clinical photodynamic therapy of cutaneous disease. Rev. Sci. Instrum. 77, 064302-1 - 8 (2006).
2005
T.H. Foster, B.D. Pearson, S. Mitra, and C.E. Bigelow. Fluorescence anisotropy imaging reveals localization of meso-tetrahydroxyphenyl chlorin in the nuclear envelope. Photochem. Photobiol. 81, 1544-1547 (2005). [Medline]
S. Mitra, E. Maugain, L. Bolotine, F. Guillemin and T.H. Foster. Temporally and spatially heterogeneous distribution of mTHPC in a murine tumor observed by two-color confocal fluorescence imaging and spectroscopy in a whole mount model. Photochem. Photobiol. 81, 1123-1130 (2005). [Medline].
Y. Chabrier-Rosello, T.H. Foster, N. Perez-Nazario, S. Mitra, and C.G. Haidaris. Sensitivity of Candida albicans germ tubes and biofilms to Photofrin-mediated phototoxicity. Antimicrob. Agents Chemother. 49, 4288-4295 (2005). [Medline]
J.D. Wilson and T.H. Foster. Mie theory interpretations of light scattering from intact cells. Opt. Lett. 30, 2442-2444 (2005). [Medline]
S. Mitra and T.H. Foster. Photophysical parameters, photosensitizer retention and tissue optical properties completely account for the higher photodynamic efficacy of mTHPC vs. Photofrin. Photochem. Photobiol. 81, 849-859 (2005). [Medline]
J.C. Finlay and T.H. Foster. Recovery of hemoglobin oxygen saturation and intrinsic fluorescence using a forward adjoint model. Appl. Optics 44, 1917-1933 (2005). [Medline]
J.D. Wilson, C.E. Bigelow, D.J. Calkins, and T.H. Foster. Light scattering from intact cells reports oxidative-stress-induced mitochondrial swelling. Biophys. J. 88, 2929-2938 (2005). [Medline]
2004
J.C. Finlay, S. Mitra, M.S. Patterson, and T.H. Foster. Photobleaching kinetics of Photofrin in vivo and in multicell tumor spheroids indicate two simultaneous bleaching mechanisms. Phys. Med. Biol. 49, 4837-4860 (2004). [Medline]
J.C. Finlay and T.H. Foster. Hemoglobin oxygen saturations in phantoms and in vivo from measurements of steady-state diffuse reflectance at a single, short source-detector separation. Med. Phys. 31, 1949-1959 (2004). [Medline]
J.C. Finlay and T.H. Foster. Effect of pigment packaging on diffuse reflectance spectroscopy of samples containing red blood cells. Opt. Lett. 29, 965-967 (2004). [Medline]
C.E. Bigelow, H.D. Vishwasrao, J.G. Frelinger, and T.H. Foster. Imaging enzyme activity with polarization-sensitive confocal fluorescence microscopy. J. Microsc. 215, 24-33 (2004). [Medline]
J.M. Bliss, C.E. Bigelow, T.H. Foster, and C.G. Haidaris. Susceptibility of Candida species to photodynamic effects of Photofrin. Antimicrob. Agents Chemother. 48, 2000-2006 (2004). [Medline]
S. Mitra and T.H. Foster. Carbogen breathing significantly enhances the penetration of red light in murine tumors in vivo. Phys. Med. Biol. 49, 1891-1904 (2004). [Medline]
2003
S. Mitra, E.M. Goren, J.G. Frelinger, and T.H. Foster. Activation of heat shock protein 70 promoter with mTHPC-photodynamic therapy reported by green fluorescent protein in vitro and in vivo. Photochem. Photobiol. 78, 615-622 (2003). [Medline]
C.E. Bigelow, D.L. Conover, and T.H. Foster. Confocal fluorescence spectroscopy
and anisotropy imaging system. Opt. Lett. 28, 695-697 (2003). [Medline]
2002
J.C. Finlay, S. Mitra, and T.H. Foster. In vivo mTHPC photobleaching in normal rat skin exhibits unique irradiance dependent features. Photochem. Photobiol. 75, 282-288 (2002). [Medline]J.M. Larkin, W.R. Donaldson, R.S. Knox, and T.H. Foster. Reverse intersystem crossing in rose bengal. II. Fluence dependence of fluorescence following 532-nm laser excitation. Photochem. Photobiol. 75, 221-228 (2002). [Medline]
K. Nakai, Y. Numaguchi, T.H. Foster, K. Shima, and M. Kikuchi. Endovascular treatment using low-power ultraviolet laser for delayed vasospasm in the rabbit carotid artery model. Am. J. Neuroradiol. 23, 1725-1731 (2002). [Medline]
S. Coutier, L.N. Bezdetnaya, T.H. Foster, R.M. Parache, and F. Guillemin. Effect of irradiation fluence rate on the efficacy of photodynamic therapy and tumor oxygenation in meta-tetra (hydroxyphenyl) chlorin (mTHPC)-sensitized HT29 xenografts in nude mice. Radiat. Res. 158, 339-345 (2002). [Medline]
2001
C.E. Bigelow, C.J. Harkrider, D.L. Conover, T.H. Foster, I. Georgakoudi, S. Mitra, M.G. Nichols, and M. Rajadhyaksha. Retrofitted confocal laser scanner for a commercial inverted fluorescence microscope. Rev. Sci. Instrum. 72, 3407-3410 (2001).C.E. Bigelow, S. Mitra, R. Knuechel and T.H. Foster. ALA and ALA-hexylester-induced protoporphyrin IX fluorescence and distribution in multicell tumor spheroids. Br. J. Cancer 85, 727-734 (2001). [Medline]
E.L. Hull and T.H. Foster. Cytochrome spectroscopy in scattering suspensions containing mitochondria and red blood cells. Appl. Spectrosc. 55, 149-154 (2001).
E.L. Hull and T.H. Foster. Steady-state reflectance spectroscopy in the P3 approximation. J. Opt. Soc. Am. A. 18, 584-599 (2001).
J.C. Finlay, D.L. Conover, E.L. Hull, and T.H. Foster. Porphyrin bleaching and PDT-induced spectral changes are irradiance dependent in ALA-sensitized normal rat skin in vivo. Photochem. Photobiol. 73, 54-63 (2001). [Medline]
S. Coutier, S. Mitra, L.N. Bezdetnaya, R.M. Parache, I. Georgakoudi, T.H. Foster, and F. Guillemin. Effects of fluence rate on cell survival and photobleaching in meta-tetra (hydroxyphenyl) chlorin-photosensitized colo26 multicell tumor spheroids. Photochem. Photobiol. 73, 297-303 (2001). [Medline]
S. Mitra, J.C. Finlay, D. McNeill, D.L. Conover, and T.H. Foster. Photochemical oxygen consumption, oxygen evolution and spectral changes during UVA irradiation of EMT6 spheroids. Photochem. Photobiol. 73, 703-708 (2001). [Medline]
2000
D.L. Conover, B.M. Fenton, T.H. Foster, and E.L. Hull. An evaluation of near infrared spectroscopy and cryospectrophotometry estimates of hemoglobin oxygen saturation in a rodent mammary tumor model. Phys. Med. Biol. 45, 2685-2700 (2000). [Medline]
S. Mitra and T.H. Foster. Photochemical oxygen consumption sensitized by a porphyrin phosphorescent probe in two model systems. Biophys. J. 78, 2597-2605 (2000). [Medline]
1999
E.L. Hull, D.L. Conover, and T.H. Foster. Carbogen-induced changes in rat mammary tumor oxygenation reported by near-infrared spectroscopy. Br. J. Cancer 79, 1709-1716 (1999). [Medline]I. Georgakoudi, P.C. Keng, and T.H. Foster. Hypoxia significantly reduces aminolaevulinic acid-induced protoporphyrin IX synthesis in EMT6 cells. Br. J. Cancer 79, 1372-1377 (1999). [Medline]
J.M. Larkin, W.R. Donaldson, T.H. Foster, and R.S. Knox. Reverse intersystem crossing from a triplet state of rose bengal populated by sequential 532- + 1064 - nm laser excitation. Chem. Phys. 244, 319-330 (1999).
1998
E.L. Hull, M. G. Nichols, and T.H. Foster. Localization of luminescent inhomogeneities in turbid media using spatially-resolved measurements of cw diffuse luminescence emittance. Appl. Optics 37, 2755-2765 (1998).E.L. Hull, M.G. Nichols, and T.H. Foster. Quantitative broadband near-infrared spectroscopy of tissue-simulating phantoms containing erythrocytes. Phys. Med. Biol.43, 3381-3404 (1998). [Medline]
I. Georgakoudi and T.H. Foster. Singlet oxygen- vs. non-singlet oxygen-mediated mechanisms of sensitizer photobleaching and their effects on photodynamic dosimetry. Photochem. Photobiol. 67, 612-625 (1998). [Medline]
I. Georgakoudi and T.H. Foster. Effects of subcellular redistribution of two nile blue derivatives on photodynamic oxygen consumption. Photochem. Photobiol. 68, 115-122 (1998). [Medline]
1997
M.G. Nichols, E.L. Hull, and T.H. Foster. Design and testing of a white light steady-state diffuse reflectance spectrometer for determination of optical properties of highly scattering systems. Appl.Optics 36, 93-104 (1997).I. Georgakoudi, M.G. Nichols, and T.H. Foster. The mechanism of photofrin photobleaching and its consequences for photodynamic dosimetry. Photochem. Photobiol. 65, 135-144 (1997). [Medline]
S.L. Gibson, J.J. Havens, T.H. Foster, and R. Hilf. Time-dependent intracellular accumulation of d-aminolevulinic acid, induction of porphyrin synthesis and subsequent phototoxicity. Photochem. Photobiol. 65, 416-421 (1997). [Medline]
1996
T.H. Foster, S.L. Gibson, and R.F. Raubertas. Response of Photofrin-sensitized mesothelioma xenografts to photodynamic therapy with 514 nm light. Br. J. Cancer 73, 933-936 (1996). [Medline]1995
Z. Hua, S.L. Gibson, T.H. Foster, and R. Hilf. Effectiveness of delta-aminolevulinic acid (d-ALA) induced protoporphyrin as a photosensitizer for photodynamic therapy in vivo. Cancer Res. 55, 1723-1731 (1995). [Medline]1994
M.G. Nichols and T.H. Foster. Oxygen diffusion and reaction kinetics in photodynamic therapy of multicell tumor spheroids. Phys. Med. Biol. 39, 2161-2181 (1994). [Medline]S.L. Gibson, T.H. Foster, R.H. Feins, R.F. Raubertas, M.A. Fallon, and R. Hilf. Effects of photodynamic therapy on xenografts of human mesothelioma and rat mammary carcinoma in nude mice. Br. J. Cancer 69, 473-481 (1994). [Medline]
S.D. Kennedy, L.S. Szczepaniak, S.L. Gibson, R. Hilf, T.H. Foster, and R.G. Bryant. Quantitative MRI of Gd-DTPA uptake in tumors: response to photodynamic therapy. Magn. Reson. Med. 31, 292-301 (1994). [Medline]
S.L. Gibson, M.L. Nguyen, T.H. Foster, G. White, and R. Hilf. Efficacy of photodynamic therapy on original and recurrent rat mammary tumors. Photochem. Photobiol. 61, 196-199 (1994). [Medline]
1993
T.H. Foster, D.F. Hartley, M.G. Nichols, and R. Hilf. Fluence rate effects in photodynamic therapy of multicell tumor spheroids. Cancer Res. 53, 1249-1254 (1993). [Medline]1992
T.H. Foster and L. Gao. Dosimetry in photodynamic therapy: oxygen and the critical importance of capillary density. Radiat. Res. 130, 379-383 (1992). [Medline]T.H. Foster. Tissue conductivity modifies the magnetic resonance intrinsic signal-to-noise ratio at high frequencies. Magn. Reson. Med. 23, 383-385 (1992). [Medline]
L.A. Sporn and T.H. Foster. Photofrin and light induces microtubule depolymerization in cultured human endothelial cells. Cancer Res. 52, 3443-3448 (1992). [Medline]
1991
T.H. Foster, R.S. Murant, R.G. Bryant, R.S. Knox, S. L. Gibson and R. Hilf. Oxygen consumption and diffusion effects in photodynamic therapy. Radiat. Res. 126, 296-303 (1991). [Medline]
T.H. Foster, M.C. Primavera, V.J. Marder, R. Hilf, and L.A. Sporn. Photosensitized release of von Willebrand factor from cultured human endothelial cells. Cancer Res. 51, 3261-3266 (1991). [Medline]