December 16, 2009
Congratulations to Dr. McAleavey!
Congratulations to Dr. Stephen McAleavey on the birth of his first child. Stephen and his wife welcomed a daughter, Laura Katherine McAleavey, on December 15. She weighed in at 7 pounds 3 ounces, was 20.7 inches long, arrived at 9:29 AM. Mom and baby are both doing well.
October 29, 2009
Dr. Diane Dalecki Elected Fellow of Acoustical Society of America
Diane Dalecki, Ph.D. (BME, RCBU) has been elected a Fellow of the Acoustical Society of America. She was recognized by the society for her
contributions to the bioeffects of sound and ultrasound.Professor Dalecki's election to Fellow was acknowledged at an awards ceremony during the 158th Meeting of the Acoustical Society of America that was held in San Antonio, TX on October 26-30, 2009.
October 1, 2009
New Collaboration between the Helguera (RIT), Dalecki, and Hocking Labs
A new collaboration, funded by the NIH, brings together the expertise of Professor Maria Helguera (Center for Imaging Sciences, RIT), Professor Diane Dalecki (BME, UR), and Professor Denise Hocking (Pharmacology & Physiology, UR). The collaborative effort focuses on developing novel, ultrasound tissue characterization techniques for engineered tissues. This work is part of a larger project, led by Drs. Dalecki and Hocking and funded by the NIH, that aims to develop ultrasound-based technologies for the field of tissue engineering.
Dr. Helguera's laboratory is devoted to advancing multimodal imaging and materials characterization techniques. Over the years, she has developed a suite of nondestructive, ultrasound-based materials characterization techniques for non-biological materials, such as polymers, ceramics, and layered materials. Through this new collaborative effort, the novel approaches that Dr. Helguera has developed and implemented for ultrasound characterization of non-biological materials will be translated to characterize the biological properties of engineered tissues. We propose to extend and apply high frequency ultrasound-based, tissue characterization techniques to monitor non-invasively biological and structural properties of cells and extracellular matrix proteins within three-dimensional engineered tissues. NIH support for the next two years will allow Dr. Helguera to spend the fall semesters and part of her summers devoted full-time to the research project as a Visiting Scientist in the Dalecki lab at the UR BME department. Drs. Helguera, Dalecki, and Hocking are all members of the Rochester Center for Biomedical Ultrasound.
September 1, 2009
Michael Richards, Ph.D. Joins the RCBU Community as a Post-Doctoral Fellow in the Doyley Lab
Please welcome Michael Richards, Ph.D. to the RCBU community. Dr. Richards will begin his post-doctoral work in Dr. Marvin Doyley's lab in the Department of Electrical and Computer Engineering. Dr. Richard's research will focus on developing and testing an advanced intravascular ultrasound system for the diagnosis of atherosclerosis. He plans to use a novel type of imaging system that is inserted, like a catheter, into blood vessels to interrogate the mechanics of arterial plaques. Dr. Richards, an alumnus of the UR, received his B.S. in BME in 2001.
July 15, 2009
Marvin Doyley (ECE) has been awarded a new NIH R01 grant titled
IVUS Detection of Rupture Prone Plaques. The overall goal of the project is to develop ultrasonic methods to assess the functional and structural properties of life-threatening atherosclerotic plaques and the arterial wall. Dr. Doyley will measure the functional properties of coronary arteries using a prototype intravascular ultrasound (IVUS) system, equipped with a dual frequency IVUS transducer (15 MHz and 30 MHz), to visualize molecules that are expressed preferentially by life-threatening atherosclerotic plaques. Ultrasound contrast agents will be used to target specific blood vessels. The outcome of the project will advance the use of ultrasound for the diagnosis of atherosclerosis.
June 30, 2009
Carol Raeman - 20 Years with the RCBU!
This month the RCBU recognizes Carol Raeman's 20 years of employment at the University of Rochester! Carol is currently a Technical Associate I working in the laboratory of Professor Diane Dalecki in the Department of Biomedical Engineering. Carol started her employment with the University in 1989 working with Professor Ed Carstensen in the Department of Electrical Engineering. During her early years of employment, Carol played a key technical role in many studies on the biological effects of lithotripter fields. Only one year after her initial hire, Carol was already a co-author on 5 papers dealing with the bioeffects of lithotripter fields and pulsed ultrasound on the kidney, chick embryo, and lung. As her career progressed, Carol contributed to many significant studies on the effects of ultrasound on tissues containing contrast agents, the mechanisms for ultrasound-induced lung damage, effects of ultrasound on the heart and neural tissue, and the interaction of very low frequency underwater sound with biological tissues. Recent areas of Carol's work include applications of ultrasound in wound healing and cell and tissue engineering.
Carol is highly skilled in both our biological and acoustic techniques, and contributes to the design and completion of a wide variety of research projects in our lab. Her experience, ingenuity, technical ability, and collaborative skills make her an enormously valuable member of our laboratory team. She has made outstanding contributions to the field of biomedical ultrasound over the years and we are very fortunate that she is a member of our lab.said Dr. Diane Dalecki.
June 16, 2009
Carlos Sevilla Awarded NIH Pre-doctoral Fellowship
Carlos Sevilla was awarded a prestigious NIH Ruth L. Kirschstein National Research Service Award Individual Pre-doctoral Fellowship. This three-year award will provide funding for Carlos' thesis research project, titled ,
Promoting Chronic Wound Healing with Ultrasound and Fibronectin. In his research, Carlos is investigating the ability of ultrasound to produce conformational changes in the extracellular matrix protein fibronectin that, in turn, stimulate cellular processes important for accelerating soft tissue wound repair. Carlos is a third year graduate student in the Department of Biomedical Engineering and his thesis research is co-advised by Dr. Denise Hocking and Dr. Diane Dalecki. Carlos is also a student member of the Rochester Center for Biomedical Ultrasound (RCBU). Carlos' research is part of a larger, multidisciplinary project, led by Drs. Dalecki and Hocking and funded by the NIH, that aims to develop the use of ultrasound for chronic wound therapy.
June 16, 2009
Drs. Hocking and Dalecki Receive NIH Funding for Summer Students
Dr. Denise Hocking and Dr. Diane Dalecki have received funding from the NIH to support the summer research projects and career development of undergraduate and high school students for two years. The funding is in response to American Recovery and Reinvestment Act (ARRA) initiatives of the National Institute of Biomedical Imaging and Bioengineering (NIBIB). Research areas of student projects focus on studying the effects of ultrasound on cell growth and protein conformation, and novel applications of acoustic radiation force. This work will contribute to a larger, multidisciplinary project, led by Drs. Hocking and Dalecki and funded by the NIH, that aims to develop novel ultrasound technologies for the field of tissue engineering.
June 5, 2009
Kelley Garvin Wins Best Student Paper Competition
Kelley Garvin won the Best Student Paper Competition at the 157th Meeting of the Acoustical Society of America held in Portland, OR from May 18-22. Her paper, titled
Ultrasound standing wave fields control the spatial distribution of cells and protein in three-dimensional engineered tissue,was recognized as the best student paper in the Biomedical Ultrasound / Bioresponse to Vibration Technical Section. Kelley presented her recent work demonstrating the use of ultrasound fields to non-invasively control the spatial locations of cells in collagen-based engineered tissues. Ultrasound standing wave fields were used to organize cells into planar bands within collagen gels, resulting in a significant two-fold increase in cell-mediated gel contraction, suggesting that ultrasound-induced cell organization leads to a differential extracellular matrix remodeling. Further, using ultrasound to spatially band endothelial cells within collagen gels resulted in vessel sprouting. These novel technologies have important applications to the fabrication of engineered tissues with desired tissue characteristics. Kelley is a third year graduate student in the Department of Biomedical Engineering (BME) and her thesis research is co-advised by Dr. Diane Dalecki and Dr. Denise Hocking. Kelley is also a student member of the Rochester Center for Biomedical Ultrasound (RCBU). Kelley's research is part of a larger, multidisciplinary project, led by Drs. Dalecki and Hocking and funded by the NIH, that aims to develop novel ultrasound technologies for the field of tissue engineering.
May 18, 2009
RCBU Members Attend Acoustical Society of America Meeting
The RCBU was well represented at the Meeting of the Acoustical Society of America held in Portland, Oregon on May 18-22, 2009, with the following presentations: Ultrasound Standing Wave Fields Control the Spatial Distribution of Cells and Protein in Three-Dimensional Engineered Tissue by Kelley A. Garvin, Denise Hocking, and Diane Dalecki. Kelley Garvin won the Best Student Paper Competition in the Biomedical Ultrasound/Bioresponse to Vibration Technical Section with this paper. Lung Hemorrhage Produced by Exposure to Underwater Acoustic Impulses by Diane Dalecki, Sally Z. Child, and Carol H. Raeman. Comparison of Unconfined Compression and Spatially Modulated Ultrasound Radiation Force Estimates of Shear Modulus by Stephen McAleavey, Erin Collins, Johanna Kelly, Etana Elegbe, and Manoj Menon.
May 15, 2009
The University announced that its engineering school will, effective July 1, be officially named the Edmund A. Hajim School of Engineering and Applied Sciences.
The naming recognizes alumnus Edmund Hajim's many decades of service and contributions to the University, including his $30 million gift commitment last fall to the School of Engineering and Applied Sciences. Hajim earned his bachelor's degree in chemical engineering at Rochester in 1958, has had a highly successful career as a senior executive for several Wall Street firms, has served for the past year as the Chairman of the University's Board of Trustees, and has been a member of the Board since 1988.
May 13, 2009
Senior Design Students Take on Ultrasound Problem for Final Project
For the last nine years, senior engineering students have helped real-life customers solve biomedical engineering problems through a two-semester Senior Design course taught by Amy Lerner, Ph.D., and Scott Seidman, Ph.D. This year, BME seniors Aaron Gelinne, Bo Wang, Andrew Bochenko, and Tony Broyld solved Dr. Paul Bigeleisen's need for a system to stabilize an ultrasound imaging transducer when inserting a needle into tissue. According to Dr. Lerner,
The UltraNeedle team was a great example of the kind of successful design process our students use to develop medical innovations. The students worked extensively with their clinical 'customer', learning about the technical challenges of the medical setting, and the demands of the end-user. They developed a simple, but elegant prototype that allowed for significant testing by representative customers. At the same time, they thoroughly considered the challenges that may be faced in manufacturing, marketing and obtaining regulatory approval for their device. We are very proud of their success, and look forward to continued development of their proposed solution.
November 11, 2008
Floyd Dunn Receives Fry Award from the International Society on Therapeutic Ultrasound
Floyd Dunn, an honorary member of the Rochester Center for Biomedical Ultrasound (RCBU), received the William J. and Francis J. Fry Award for his contributions to the general area of biophysics and bioeffects of ultrasound, from the International Society on Therapeutic Ultrasound on September 12, 2008 in Minneapolis, MN. An award plaque and honorarium were presented. Dr. Dunn (Professor Emeritus of the University of Illinois) has been an honorary member of the RCBU since its inception in 1986.
October 30, 2008
Not only is the University of Rochester the region's largest employer - it's also one of the best places in the nation for scientists to work, according to The Scientist magazine.
It's gratifying to be recognized for the research environment that we've worked hard to create,said Bradford C. Berk, M.D., Ph.D., CEO of the Medical Center.
This is an institution founded on the principle of interdisciplinary collaboration. Our scientists' satisfaction plays an important role in the ultimate success of our research enterprise, and helps us truly achieve
Medicine of the Highest Order.
October 17, 2008
Edmund A. Hajim, University of Rochester Chairman of the Board of Trustees and a 1958 engineering school graduate, announced his plans to give to the SEAS $30 million. The gift, which will be paid over several years, will provide scholarships for students with significant financial needs; it will also be put towards the endowment.
October 15, 2008
New Five-Year NIH Grant to Study Ultrasound and Wound Healing Awarded to a Multi-Disciplinary Team of Engineers, Scientists, and Physicians
Diane Dalecki, Ph.D. (BME) and Denise Hocking, Ph.D. (Pharmacology and Physiology) are multi-PIs on a new, R01 NIH grant entitled "Mechanisms for Wound Healing with Ultrasound." The grant was awarded by the NIBIB for a five-year period. The overall goal of the project is to identify key biological and physical mechanisms for ultrasound-enhanced soft tissue wound healing in order to develop the use of ultrasound for chronic wound therapy. The guiding hypothesis of the work is that mechanical forces associated with ultrasound propagation are capable of triggering conformational changes to extracellular matrix proteins that in turn enhance cell growth and contractility, stimulate cellular migration, promote collagen organization and mechanical strength, and increase blood flow to tissues. The multi-disciplinary team of engineers, basic scientists, and physicians on the project are Ingrid Sarelius, Ph.D. (Pharmacology and Physiology), Sheryl Gracewski, Ph.D. (ME), Sabine Brouxhon, M.D. (Emergency Medicine), Charles Francis, M.D. (Medicine/Hematology), and Edwin Carstensen, Ph.D. (ECE).
August 30, 2008
Grant received to develop ultrasound technologies to detect, monitor, and assist in the treatment of breast lesions
Through the Susan G. Komen Foundation, Dr. Kaisar Alam and Dr. Deborah Rubens (RCBU Associate Director) received a grant to develop ultrasound technologies to detect, monitor, and assist in the treatment of breast lesions. The project is a collaborative effort between the Riverside Research Institute and the University of Rochester. Dr. Alam, an alumnus of the University of Rochester, received his Ph.D. in Electrical and Computer Engineering under the supervision of Kevin Parker, Ph.D. Through this three-year project, the team will develop elastography and ultrasound tissue characterization techniques to detect and monitor breast lesions with the ultimate objective of developing a reliable, clinically practical method of identifying benign breast lesions.
August 6, 2008
The inventors of the "Blue Noise Mask," a display and printing technology that rapidly generates high-quality images developed at the University of Rochester in the late 1980s, are pleased that the patents for their technology will be able to be enforced in a lawsuit against Microsoft because of the recent decision of a federal appellate court.
July 15, 2008
February 25, 2008
Research published in 1997 by Dr. Ted Christopher, a former UR doctoral student advised by Kevin Parker, Ph.D., has led to the licensing of tissue harmonic imaging to General Electric, the world's top manufacturer of ultrasound equipment. The modality will be used in 80% of the US ultrasound market.
February 22, 2008
Benjamin Castaneda Wins Honorable Mention at SPIE!
Benjamin Castaneda received an honorable mention for his presentation of measurement of thermally-ablated lesions in sonoelastographic images using level set methods.
January 28, 2008
Karl Schwarz, M.D., receives the UR Board Excellence Award in the Physician Category
Karl Schwarz, M.D., professor of Medicine in the Cardiology Division and Director of the UR Echocardiography Laboratory, and RCBU member, received the UR Board Excellence Award in the Physician category. The Chairman's Excellence Awards are received by employees whose professional and personal standards exemplify quality patient care, mirroring the values of the institution's Strong Commitment initiative: integrity, compassion, accountability, respect and excellence.
December 21, 2007
Technologies developed at the University of Rochester are among the most productive in the nation, according to a report by the Association of University Technology Managers (AUTM). For the sixth year in a row, the University is among the top ten institutions in the nation in terms of the amount of royalty revenue it receives from its licensed technologies.
December 1, 2007
RCBU Members Receive Grant to Develop Tool for Early Detection and Monitoring of Liver Disease
RCBU members Kevin Parker (PI), Robert Lerner, Stephen McAleavey, and Diane Dalecki received funding from the Stanford University Center on Longevity for the project titled,
Elastography in the Early Detection and Management of Liver Disease. The goal of this project is to develop a safe, non-invasive, inexpensive tool for the early detection and monitoring of liver disease.
December 1, 2007
The Stanford Center on Longevity Awards Stephen McAleavey, Ph.D. Grant to Study Incontinence Management
Stephen McAleavey (PI) was awarded a grant from the Stanford Center on Longevity for research on a
Wireless Urine Monitor and Aids for Bladder Training and Incontinence Management.The goal of this project is to develop an assistive device for bladder training. The device, which incorporates a disposable sensor and wireless monitor, records the time of incontinence episodes. Urinary incontinence affects at least 10% of the age 65 or older population, and as many as 60% of those living in nursing homes.
November 11, 2007
David Blackstock, Ph.D. receives the Rossing Prize in Acoustics Education from the ASA
David Blackstock was awarded the Rossing Prize in Acoustics Education from the Acoustical Society of America (ASA). The award was presented at the fall 2007 ASA Meeting in New Orleans. Dr. Blackstock presented the following paper in response to the award: D.T. Blackstock,
Songs my students sang to me,J. Acoust. Soc. Am. 122, 3026, 2007.
September 24, 2007
NIH awards grant to study Ultrasound Technologies for Tissue Engineering
Diane Dalecki, Ph.D. and Denise Hocking, Ph.D., serve as multi-PIs on a grant from the NIH NIBIB titled
Ultrasound Technologies for Tissue Engineering. The overall goal is to develop ultrasound-based enabling technologies for the fabrication and monitoring of functional, 3D artificial tissues. Through the project, they will develop the use of ultrasound to regulate the structure and organization of the extracellular matrix in order to stimulate cell processes that are critical for engineering functional tissue constructs. Current studies are testing the ability of ultrasound to produce conformational changes in fibronectin, an extracellular matrix protein that plays key roles in regulating cell growth and migration. Working with co-investigators Stephen McAleavey, Ph.D. and Sheryl Gracewski, Ph.D., the team is also developing and applying new ultrasound imaging and tissue characterization techniques to noninvasively monitor the material and biological properties of engineered tissues, and to validate the measurements through mechanical testing and finite element modeling.
September 19, 2007
U.S. Navy Awards Grant to Study Neural Effects of Underwater Sound to John Olschowka, Ph.D. and Diane Dalecki, Ph.D.
John Olschowka (PI, Dept. of Neurobiology & Anatomy) and Diane Dalecki (co-I) received a two-year grant from the U.S. Navy titled
Neural Effects of Underwater Sound.Underwater sound fields are used for numerous commercial and military applications, including imaging, oil exploration, mapping the ocean, and harbor surveillance. Sponsored by the U.S. Navy, Drs. Olschowka and Dalecki have embarked on a new collaborative project that will investigate the interactions of continuous and impulsive underwater sound fields with the brain and spinal cord. The Olschowka lab, in the UR Department of Neurobiology and Anatomy, has long-standing expertise in examining injury to neural tissues, including trauma, using molecular, protein, and immunohistochemical techniques. Using the acoustic sources and technical expertise of the Dalecki lab, the team will investigate neural bioeffects of sound fields at frequencies ranging from 500 Hz-30 kHz. To also study the effects of acoustic impulses, the facilities and expertise available at Hydroacoustic, Inc. will be employed to generate underwater impulsive sound fields using an air gun system. Neural tissues of animals exposed to these continuous and impulsive underwater sound fields will be assessed for vascular damage, axonal injury, and glial activation. Results of this project will help to establish safe exposure guidelines for human divers and marine life exposed to underwater sound fields.
September 1, 2007
National Science Foundation awards grant to Study Dynamic Response of Constrained Bubbles to Acoustic Excitation
Sheryl Gracewski (PI) and Diane Dalecki (co-PI) were awarded an NSF grant from the CMMI division titled
Dynamic Response of Constrained Bubbles to Acoustic Excitation.This project will theoretically and experimentally characterize the linear and nonlinear dynamics of acoustically excited bubbles that are constrained within tubes and channels. The results of this work will be directly relevant to the use of ultrasound microbubble contrast agents in diagnostic imaging and new ultrasound-based therapies.
September 1, 2007
Researchers receive NIH grant to study 3D Prostate Cancer Imaging Based on Crawling Wave Excitation
Deborah Rubens (PI) and Kevin Parker (co-I) were awarded a grant from the NIH titled
3D Prostate Cancer Imaging Based on Crawling Wave Excitation.The goal of this project is to develop a novel 3D scanner, based on crawling wave technology, for application to prostate cancer.
July 7, 2007
Edwin Carstensen, Ph.D., receives ASA’s Helmholtz-Rayleigh Interdisciplinary Silver Medal
The Acoustical Society of America's Helmholtz-Rayleigh Interdisciplinary Silver Medal was awarded to Edwin Carstensen (Founding RCBU Director) at the spring 2007 Acoustical Society of America Meeting in Salt Lake City. The award recognizes Dr. Carstensen's outstanding contributions to the physics of biomedical ultrasound.
May 16, 2007
A five-story facility that pairs biomedical engineering and optics in an environment of teaching laboratories, high-tech demonstration areas, and gathering spaces for collaboration will officially open May 17 as the Robert B. Goergen Hall for Biomedical Engineering and Optics on the University of Rochester's River Campus.
March 15, 2007
Benjamin Castaneda recognized in several worldwide competitions
Benjamin Castaneda was the winner of the Predictive Model Contest 2007 sponsored by Humana, Inc. Ben was also a finalist in the New Investigator Award Competition at the 2007 AIUM Annual Convention. He also received an honorable mention in the Mondialogo Engineering Award 2007 sponsored by UNESCO and Daimler.
January 23, 2007
Diane Dalecki, associate professor of biomedical engineering, has been appointed the new director of the Rochester Center for Biomedical Ultrasound (RCBU) at the University of Rochester. Created in 1986, the RCBU provides a unique environment where researchers from many institutions can join together to investigate the use of very high frequency sound waves in medical diagnosis and therapy.
June 17, 2005
Kevin J. Parker, dean of the School of Engineering and Applied Sciences and professor of electrical and computer engineering, radiology, and bioengineering at the University of Rochester, has been named the William F. May Professor of Engineering.
January 29, 2004
Developers of a University of Rochester computer technology have won a major court ruling against Microsoft Corporation. An Arizona judge has ruled that Microsoft infringed on patents on the technology, called
Blue Noise Mask,which makes possible the rapid creation of high-quality halftone images.
July 29, 2002
Distorted Ultrasound Waves Produce Clearer Images: University Technology Licensed to Medical Ultrasound Company
A technology that greatly sharpens ultrasound images by capitalizing on a distortion that arises in tissue has been licensed to Acuson Corporation in Mountain View, Calif. The technique was developed at the University of Rochester's Center for Biomedical Ultrasound by several researchers over the course of three decades. Acuson, which has been granted a nonexclusive right to the patent, is a leading worldwide manufacturer and service provider of diagnostic medical ultrasound systems that generate, display, archive, and retrieve ultrasound images.
June 28, 2001
Pioneering research in both biotechnology and imaging enabled the University of Rochester to double the amount of revenue its basic research earned this year. The advance, to $29.5 million for the fiscal year that ends June 30, 2001, is more than double the $13.5 million that companies paid last year and 10 times the $2.9 million in royalties from the previous year.
December 10, 1999
A halftoning technology developed by University of Rochester electrical engineers has been licensed to Hewlett-Packard Co., the world's largest maker of printers for computer use. The licensing comes as part of a settlement agreed upon last week by HP and Research Corporation Technologies (RCT) of Tucson, Ariz., which had filed a patent infringement lawsuit against HP. No other terms of the settlement were disclosed.
July 27, 1999
The University of Rochester dean of engineering has received one of the highest prizes in the field of medical ultrasound for his research, which is helping to spur new ways of thinking about how to find cancers of the breast, liver, and prostate.
May 8, 1998
Experts in emergency medicine and ultrasound have teamed up at the University of Rochester to better one of the most vital tools in the paramedic's array of equipment: endotracheal tubes, the flexible tubes inserted in the throats of hundreds of thousands of unconscious patients each year to ensure continuous delivery of oxygen to their lungs. The new device, soon to receive a U.S. patent, takes advantage of the same ultrasound technology now used by physicians to observe babies developing in the womb.
June 6, 1997
Hugh G. Flynn, an internationally recognized expert on ultrasonic waves' violent effects on air bubbles in liquids -- a topic with applications in energy, medicine, and manufacturing -- died at the Kirkhaven Presbyterian Home in Rochester on May 23. Flynn, professor emeritus of electrical engineering at the University of Rochester, was 84.
October 18, 1996
Two University of Rochester researchers have invented a new "phantom" for quicker, more accurate testing and standardization of ultrasound scanners.
April 27, 1995
If you're surprised by the speed with which your next printer produces high-quality images, you might have the University of Rochester to thank.
March 7, 1995
Electrical engineer Robert C. Waag has been named Arthur Gould Yates Professor of Engineering at the University of Rochester.
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