URMC Pathology/Morphology Imaging Core


Visit the Pathology/Morphology Imaging Core website

 

Director

Linda Callahan, Ph.D.

Mission Statement

The URMC Pathology/Morphology Imaging Core strives to provide UR researchers the ability to obtain high quality imaging data using state-of-the-art microscopy instruments.  The Core also aims to be the information hub for UR resources centering around histological processing, imaging, and image processing and to serve as a conduit for communication of imaging researchers on campus.

Statement of Core Services/Functions

The PMIC Core houses three high resolution research microscopes that provide researchers the ability to obtain qualitative and quantitative imaging-based data from tissue sections or cell cultures.  Expertise is provided both for the design of experiments as well as for the obtainment of images and software analysis.  

PMIC Core personnel aid investigators in determining possible resources within the University that can section and immunohistochemically or histologically process the tissue that will eventually be examined using Core instruments.  Guidance for quantitative assessment of image-based data is also provided.  Core personnel are able to perform both the imaging and quantitation of data for investigators that are not familiar with microscopic research technology. 

Specialized Equipment

  • Leica TCS SP Confocal Microscope, with both upright and inverted imaging capacity.  Currently this instrument has 3-color simultaneous imaging
  • Olympus Vanox T Fluorescent Microscope (epifluorescence model).  This instrument is a  standard lluorescence imaging microscope, with available filters that include UV, green, red and an attached digital camera.
  • MicroBrightfield StereoInvestigator Software for image analysis
  • Pixcell II Arcturus Laser-Capture Microdissection instrument.  Captures individual cells.

Faculty User Group

The following faculty members have been invited to serve on the PMIC faculty user group:
Bruce Fenton
Tom Foster
Julie Fudge
Barbara Iglewski
Michel Koo
Jim Miller
Maiken Nedergaard
Eddie Schwarz
David Yule
Brian Ward