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Recent works:

Invited talk on recent works in my group developing intermolecular multiple-quantum coherences  for a series of new applications in MRI:

Z. Chen, J. Zhong, "Theoretical Formalism and Direct Measurement of Diffusion and Relaxation Rates of Intermolecular Multiple-Quantum Coherences." 41st Experimental NMR Conference (ENC), Pacific Grove, CA, April 10-14, 2000 .


Reports on recent works in my group developing intermolecular multiple-quantum coherences  for a series of new applications in MRI:

Z. Chen, S. D. Kennedy, J. Zhong. "Theoretical and experimental confirmation of intermolecular dipolar effects under time-averaged magnetic filed gradients." Chem. Phys. Lett., 313, 217-224 (1999)

J. Zhong, Z. Chen, E. Kwok. "In vivo intermolecular double-quantum imaging on a clinical 1.5T MR scanner." Magn. Reson. Med. 43:335-341(2000)

J. Zhong, Chen Z. Kwok E. "New image contrast mechanisms in intermolecular double-quantum coherence human MR imaging." In press, J. Magn. Reson. Imag. (2000)

Z. Chen, Zhong J. "Unconventional diffusion behaviors of intermolecular multiple-quantum coherences in nuclear magnetic resonance." Submitted to J. Chem. Phys. (1999)

Z. Chen, Kennedy SD, Zhong J. "Quantitation of intermolecular dipolar effects in NMR spectroscopy and imaging based on demagnetizing field theory." Submitted to Mag. Reson. Materials Phys. Bio. Med. (2000)

J. Zhong, Z. Chen, E. Kwok. "fMRI of auditory stimulation with intermolecular double-quantum coherences at 1.5T." Submitted to Magn. Reson. Med. (2000)

J. Zhong, Z. Chen, E. Kwok. "Enhanced sensitivity to molecular diffusion with intermolecular multiple-quantum coherences: implications and potential applications." Submitted to Magn. Reson. Med. (2000)


Reports on high resolution fast imaging of water/fat in musculoskeletal applications:

WE Kwok, SM Totterman, J. Zhong. "Three-dimensional interleaved water and fat image acquisition with chemical-shift correction." In press, Magn. Reson. Med. (2000)

WE Kwok, SM Totterman, J. Zhong. "Interleaved water and fat dual-echo spin echo imaging with intrinsic chemical-shift elimination." Submitted, J. Magn. Reson. Imag. (2000)


Reports on new applications of fMRI in tumor study:

J. Zhong, W.E. Kwok, P. Okunieff. "FMRI for Monitoring Dynamic Changes in Brain Oxygenation / Blood Flow: Potential Application for Tumor Response to Carbogen Treatment," In press, Oxygen Transport to Tissue XXII, Proceedings of the 27th annual meeting of the International Society on Oxygen Transport to Tissue. (Dunn, J.F. and H.M. Swartz eds), Pabst Science Publishers. Lengerich. (2000).


Reports on new MRI technique for brain diffusion-weighted imaging:

Chen Z, Kwok E, Zhong J. "Optimized gradient pulse design for fast diffusion-weighted MR imaging on a clinical Scanner." Radiology, 123(P):502 (1999).


Selected previous works:

  1. Takashi Yoshiura, Jianhui Zhong, Dean K. Shibata, Wingchi E. Kwok, David A. Shrier, Yuji Numaguchi, "Functional MRI Study of Auditory and Visual Oddball Tasks." NeuroReport, 10, 1683-1688, (1999).
  2. M. D. Does, J. Zhong, and J. C. Gore, "In-Vivo Measurement of ADC change due to Intravascular Susceptibility Variation," Magn. Reson. Med. 41, 236-240 (1999)
  3. J. Zhong, R. P. Richard, R.K. Fulbright, J. C. Gore. "Quantitation of Intravascular and Extravascular Contributions to BOLD Effects Induced by Alteration in Oxygenation or Intravascular Contrast Agents." Magn. Reson. Med., 40, 526 (1998)
  4. J-H. Gao, J. Zhong, and P. Fox, "Functional MRI", in Stroke: Pathophysiology, Diagnosis and Management, 3rd edition, edited by H.J.M. Barnett, J. P. Mohr, B. M. Stein and F. M. Yatsu, Churchill Livingstone International, 1998
  5. J. Zhong, O.A.C. Petroff, J. C. Gore, J.W. Prichard. "Reversible, reproducible reduction of brain water apparent diffusion coefficient by cortical electroshocks," Magn. Reson. Med., 37,1, (1997)
  6. A. W. Anderson, J. Zhong, O. A. C. Petroff, A. Szafer, B. R. Ransom, J. W. Prichard and J. C. Gore. "Effects of Osmotically Driven Cell Volume Changes on Diffusion Weighted Imaging of the Rat Optic Nerve," Magn. Reson. Med., 35, 162-167, (1996)
  7. R. P. Kennan, J. Zhong, and J. C. Gore. "Effects of magnetic susceptibility variations on the apparent diffusion measured by NMR," in Diffusion and Perfusion: Magnetic Resonance Imaging, edited by D. Le Bihan, Raven Press, (1995)
  8. J. Zhong, O.A.C. Petroff, J.W. Prichard, and J.C. Gore. "Barbiturate-reversible reduction of water diffusion coefficient in flurothyl-induced status epilepticus in rats." Magn. Reson. Med. 33, 253 (1995)
  9. A. Szafer, J. Zhong, and J.C. Gore, "Theoretical Model for Water Diffusion in Tissues", Magn. Reson. Med. 33, 697 (1995)
  10. J.W. Prichard, J. Zhong, O. A. C. Petroff, and J. C. Gore. "Diffusion-Weighted NMR Imaging Changes Caused by Electrical Activation of the Brain." NMR in Biomed. 8, 359-364 (1995)
  11. A. Szafer, J. Zhong, A. W. Anderson, J. C. Gore. "Diffusion-Weighted Imaging in Tissue: Theoretical Models." NMR Biomed., 8, 280 (1995)
  12. R.P. Kennan, J. Gao, J. Zhong, and J.C. Gore. "A General Model of Microcirculatory Blood Flow Effects in Gradient Sensitized MRI." Med. Phys., 21, 539-545 (1994)