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  Research Topics in Progress  

AIMS:

Development and applications of fMRI techniques; the design and study of new fMRI techniques and instrumentation for medical diagnostic and neuroscience applications; quantitative studies of biophysical basis in new fMRI techniques such as intermolecular multiple-quantum coherences (iMQC) and diffusion-weighted imaging (DWI).

Research Projects and Examples (click on images at the left for additional links):

Development of echo planar and spiral scan techniques for "snap shot" imaging on our 1.5T MRI scanner; development of MRI methods for functional imaging of tumor physiology based on oxygenation susceptibility and/or flow effects at high fields.


Applications of functional MRI in neuroscience: language, reading, attention, memory, visual processing, sensorimotor systems, physiological and functional difference between the normal and deaf subjects.

New applications of Diffusion Weighted Imaging (DWI) in epilepsy and seizure models in animals and humans: development of DW-EPI techniques at 1.5 whole-body scanner and 9.4T small-bore scanner.

BOLD imaging of tumor oxygenation

Development of intermolecular multiple-quantum coherence (iMQC) MR imaging technique.

Clinical Research Collaborators in the Department:

Development of high-resolution fast imaging technique for anatomic and functional studies in musculoskeletal studies.

Research Grants:

National Institutes of Health
University of Rochester Cancer Center - Discovery Fund
Consordium on HIV MRS studies