Division of Diagnostic and Interventional Neuroradiology

2001

1. Larheim TA, Westesson P-L, Sano T. MR grading of temporomandibular joint effusion: correlation with subgroups of disk displacement a closed mouth, condyle marrow abnormalities and pain. Int J Oral Maxillofacial Surg 2001;30:104-112.

2. Larheim TA, Katzberg RW, Westesson P-L, Tallents RH, Moss M, Sano T. MR evidence of temporomandibular joint fluid and condyle marrow alterations: occurrence in asymptomatic volunteers and symptomatic patients. Int J Oral Maxillofac Surg 2001;30:113-117.

3. Honda K, Larheim TA, Sano T, Hashimoto K, Shinoda K, Westesson P-L. Temporomandibular joint: Thickening of the glenoid fossa in osteoarthritis of the temporomandibular joint. An autopsy study. Dentomaxillofacial Radiology. A Journal of Head and Neck Radiology 2001;30:10-13.

4. Larheim TA, Westesson P-L, Sano T. Temporomandibular joint disk displacement: Comparison in asymptomatic volunteers and patients. Radiology 2001;218:428-432.

5. Honda K, Larheim TA, Johannessen S, Arai Y, Shinoda K, Westesson P-L. Orthocubic computed tomography of the temporomandibular joint: comparison with hypocycloidal tomography. Oral Surg Oral Med Oral Pathol 2001;91:239-243.

6. Eriksson L, Westesson P-L. Discectomy as an effective treatment for painful TMJ internal derangement. J Oral Maxillofac Surg 2001;59:750-8.

7. Vikhoff-Baaz B, Malmgren K, Jönsson L, Starck G, Ljungberg M, Forssell-Aronsson E, Uvebrant P, Ekholm S. Lateralization with magnetic resonance spectroscopic imaging in temporal lobe epilepsy: an evaluation of visual and region-of-interest analysis of metabolite concentration. Neuroradiology (2001) 43: 721-727.

8. Ekholm SE, Björk-Eriksson T, Western A, Nellström H, Jonsson E, Johansson A, Lönn L, Mercke C and Tollesson PO. MRI staging using gadodiamide for soft-tissue tumors of the head and neck region. Results from a phase II Trial and a 5-year clinical follow-up. European Journal of Radiology 39 (2001) 168-175.

9. Danielsson AJ, Cederlund CG, Ekholm S, Nachemsson AL. The prevalence of disc aging and back pain after fusion extending into the lower lumbar spine – a matched MRI study twenty-five years after surgery for adolescent idiopathic scoliosis. ACTA Radiologica 42 (2001) 187-197.

10. Vikhoff B, Starck G, Ljunberg M, Forssell-Aronsson E and Ekholm S. Effects of k-space filtering and image interpolation on image fidelity in (1)H MRSI. Magn Reson Imaging 2001 Nov; 19(9):1227-34 PMID: 11755733 [PubMed – in process]

11. Tullberg M, Jensen C, Ekholm S and Wikkelso C. Normal pressure hydrocephalus: Vascular white matter changes on MRI must not exclude patients from shunt surgery. AJNR American Journal of Neuroradiology 2001 Oct 22:1665-1673.

12. Rödholm M, Starmark J-E, Ekholm S and vonEssen C. Organic psychiatric disorders after aneurysmal SAH: outcome and associations with age, bleeding, severity and arterial hypertension. Accepted for publication ACTA Neurologica Scandinavica 2001.

2002

1. Sano T, Widmalm S-E, Westesson P-L, Yamaga T, Yamamoto M, Takahashi K, Michi K-I, Okano T. Acoustic characteristics of sounds from temporomandibular joints with and without effusion: an MRI study. J Oral Rehab 2002;29:161-166.

2. Westesson P-L, Lee RK, Ketkar MA, Lin EP. Underdiagnosis and undertreatment of osteoporosis. The Lancet 2002;360:9348.

3. Kinoshita T, Moritani T, Shrier DA, Wang HZ, Hiwatashi A, Numaguchi Y, Westesson P-L. Secondary degeneration of the substantia nigra and coritospinal tract after hemorrhagic middle cerebral artery infarction: diffusion-weighted MR findings. Mag Reson Med Sci 2002;1:175-178.

4. Bech E, Lycke J, Gadeberg P, Hansen H.J., Malmeström C, Andersen O, Christensen T, Ekholm S, Haahr S, Höllsberg P, Bergström T, Svennerholm B, Jakobsen J. A randomized, double-blind, placebocontrolled MRI study of anti-herpes virus therapy in MS. Neurology 2002;58: 31-36.

5. Tullberg M, Hultin L, Ekholm S, Månsson J-E, Fredman P, Wikkelso C. White matter changes in normal pressure hydrocephalus and Binswanger disease: specificity, predictive value and correlations to axonal degeneration and demyelination. Acta Neurol Scand 2002: 105: 417-426.

6. Ljungberg M, Starck G, Vikhoff-Baaz B, Alpsten M, Ekholm S, Forssell-Aronsson E. The magnitude of signal errors introduced by ISIS in quantitative 31P MRS. MAGMA 2002 Mar;14(1):30-8.

7. Lagerstrand KM, Lehmann H, Starck G, Vikhoff-Baaz B, Ekholm S, Forssell-Aronsson E. Method to correct for the effects of limited spatial resolution in phase-contrast flow MRI measurements. Magn Reson Med. 2002 Nov;48(5):883-9. 

2003

1. Sunnerhagen KS, Johansson K, Ekholm S. Rehabilitation problems after acute disseminated encephalomyelitis: four cases. J Rehabil Med 2003 Jan;35(1):20-5.

2. Hiwatashi A, Moritani T, Numaguchi Y, Westesson P-L. Increases in vertebral body height after vertebroplasty. AJNR Am J Neuroradiol. 2003;24(2):185-9.

3. Ketkar M, Shrier D. An allergic reaction to intraarterial nonionic contrast material. AJNR Am J Neuroradiol. 2003 Feb;24(2):292.

4. Litman RS, Weissend EE, Shibata D, Westesson P-L. Developmental changes of laryngeal dimensions in unparalyzed sedated children. Anesthesiology 2003;98:41-45.

5. Ashton EA, Takahashi C, Berg MJ, Goodman A, Totterman S, Ekholm S. Accuracy and reproducibility of manual and semiautomated quantification of MS lesions by MRI. J Magn Reson Imaging. 2003 Mar;17(3):300-8.

6. Yuasa H, Kurita K, Westesson PL. External validity of a randomised clinical trial of temporomandibular disorders: analysis of the patients who refused to participate in research. Br J Oral Maxillofac Surg. 2003 Apr;41(2):129-31.

7. Lee PL, Yiannoutsos CT, Ernst T, Chang L, Marra CM,Jarvic J, Richards T, Kwok E, Kolson DL, Tang CY, Schifitto G, Ketonen LM, Meyerhoff DJ, Lenkinski RE, Gonzalez RG, Navia BA. A multi-center 1H MRS study of the AIDS dementia complex: Validation and preliminary analysis. J Magn Reson Imaging 2003 Jun;17(6):625-33.

8. Yuasa H, Kurita K, Westesson P-L. External validity of a randomized clinical trial of temporomandibular disorders: analysis of the patients who refused to participate in research. Short Communication. Br J Oral Maxillofac Surg 2003;41:129-131.

9. Hiwatashi A, Garber T, Moritani T, Kinoshita T, Westesson P-L. Diffusion-weighted MR imaging of Neuro-Behcet’s disease: A case report. Neuroradiology. 2003 Jul;45(7):468-71. Epub 2003 Jun 18.

10. Abdelhalim AN, Moritani T, Richfield E, Ekholm SE, Westesson PL.
    Epidermal nevus syndrome: megalencephaly with bihemispheric and cerebellar involvement: imaging and neuropathologic correlation. J Comput Assist Tomogr. 2003 Jul-Aug;27(4):534-7.

11. Ljungberg M, Sunnerhagen KS, Vikhoff-Baaz B, Starck G, Forssell-Aronsson E, Hedberg M, Ekholm S, Grimby G. 31P MRS evaluation of fatigue in anterior tibial muscle in postpoliomyelitis patients and healthy volunteers. Clin Physiol Funct Imaging. 2003 Jul;23(4):190-8.

12. Kinoshita T, Moritani T, Shrier DA, Hiwatashi A, Wang HZ, Numaguchi Y, Westesson P-L. Diffusion-weighted MR imaging of posterior reversible Leukoencephalopathy syndrome. A pictorial essay. Clin Imaging. 2003 Sept-Oct; 27(5):307-15.

13. Hiwatashi A, Kinoshita T, Moritani T, Wang HZ, Shrier DA, Numaguchi Y, Ekholm SE, Westesson PL. Hypointensity on diffusion-weighted MRI of the brain related to t2 shortening and susceptibility effects. AJR Am J Roentgenol. 2003 Dec;181(6):1705-9.

2004

1. Sano T, Yamamoto M, Okano T, Gokan T, Westesson PL. Common abnormalities in temporomandibular joint imaging. Curr Probl Diagn Radiol. 2004 Jan-Feb;33(1):16-24.

2. Hiwatashi A, Danielson B, Moritani T, Bakos RS, Rodenhause TG, Pilcher WH, Westesson PL. Axial Loading during MR Imaging Can Influence Treatment Decision for Symptomatic Spinal Stenosis.AJNR Am J Neuroradiol. 2004 Feb;25(2):170-174.

3. Lin EP, Ekholm S, Hiwatashi A, Westesson PL. Vertebroplasty: cement leakage into the disc increases the risk of new fracture of adjacent vertebral body. AJNR Am J Neuroradiol. 2004 Feb;25(2):175-80

4. Westesson PL, Oka M, Hiwatashi A, Moritani T. Vertebroplasty - how to do it. Neurographics 2004; http://www.neurographics.org/3/2/2/

5. Moritani T, Numaguchi Y, Lemer NB, Rozans MK, Robinson AE, Hiwatashi A, Westesson PL.Sickle cell cerebrovascular disease: usual and unusual findings on MR imaging and MR angiography. Clin Imaging. 2004 May-Jun;28(3):173-86.

6. Moritani T, Hiwatashi A, Shrier DA, Wang HZ, Numaguchi Y, Westesson PL. CNS vasculitis and vasculopathy: efficacy and usefulness of diffusion-weighted echoplanar MR imaging. Clin Imaging. 2004 Jul-Aug;28(4):261-70.

7. White FA, Zwemer FL Jr, Beach C, Westesson PL, Fairbanks RJ, Scialdone G. Emergency department digital radiology: moving from photos to pixels. Acad Emerg Med. 2004 Nov;11(11):1213-22.

8. Sano T, Westesson PL, Yamamoto M, Okano T. Differences in temporomandibular joint pain and age distribution between marrow edema and osteonecrosis in the mandibular condyle. Cranio. 2004 Oct;22(4):283-8.

9. Ekholm S, et al. An unusual quadrature artefact – its cause and effects in spectroscopy and imaging. Work-in-progress

10. Flinck A, Ekholm S, Nannmark U, Bagge U. Nailfold capillary flow changes and discomfort caused by contrast media. Work-in-progress.

2005

1. Andrell P, Jensen C, Norrsell H, Ekre O, Ekholm S, Norrsell U, Eliasson T, Mannheimer C, Blomstrand C. White matter disease in magnetic resonance imaging predicts cerebral complications after coronary artery bypass grafting. Ann Thorac Surg. 2005 Jan;79(1):74-9; discussion 79-80.

2. Moritani T, Smoker WR, Sato Y, Numaguchi Y, Westesson PL. Diffusion-weighted imaging of acute excitotoxic brain injury. AJNR Am J Neuroradiol. 2005 Feb;26(2):216-28.

3. Kinoshita T, Moritani T, Hiwatashi A, Numaguchi Y, Wang HZ, Westesson PL, Sugihara S, Matsusue E, Fujii S, Ohama E, Ogawa T. Clinically silent choroid plexus cyst: evaluation by diffusion-weighted MRI. Neuroradiology. 2005 Apr;47(4):251-5. Epub 2005 Mar 24.

4. Petersson A, Eriksson L, Westesson PL. MR images mimic disc after discectomy. Dentomaxillofac Radiol. 2005 Jul;34(4):237-9.

5. Kinoshita T, Moritani T, Hiwatashi A, Wang HZ, Shrier DA, Numaguchi Y, Westesson PL. Conspicuity of diffuse axonal injury lesions on diffusion-weighted MR imaging. Eur J Radiol. 2005 Oct;56(1):5-11.

6. Hiwatashi A, Sidhu R, Lee RK, deGuzman R, Piekut DT, Westesson PL. Kyphoplasty versus vertebroplasty for increase in vertebral body height: a cadaveric study. Radiology. 2005 Dec;237(3):1115-9.

7. Losee JE, Feldman E, Ketkar M, Singh D, Kirschner RE, Westesson P-L, Cooper G, Mooney MP and Bartlett SP.  Nonsynostotic occipital plagiocephaly:  radiographic diagnosis of the "sticky suture".  Plas Reconstr Surg. December 2005;16(7):1860-1869.

2006

1. Hiwatashi A, Zhong J, Ekholm SE, Westesson PL. Fractional anisotropy is higher in Heschl’s gyrus than in superior temporal gyrus in normal subjects. Acad Radiol. 2006 Jan;13(1):73-6.

2. Ni H, Kavcic V, Zhu T, Ekholm S, Zhong J. Effects of number of diffusion gradient directions on derived diffusion tensor imaging indices in human brain. AJNR Am J Neuroradiol. 2006 Sep;27(8):1776-81.

2007

1. Hiwatashi A, Ohgiya Y, Kakimoto N, Westesson PL. Cement leakage during vertebroplasty can be predicted on preoperative MRI. AJR Am J Roentgenol. 2007 Apr;188(4):1089-93.

2. Hiwatashi A, Westesson PL. Vertebroplasty for osteoporotic fractures with spinal canal compromise. AJNR Am J Neuroradiol. 2007 Apr;28(4):690-2.

3. Hiwatashi A, Westesson PL. Patients with osteoporosis on steroid medication tend to sustain subsequent fractures. AJNR Am J Neuroradiol. 2007 Jun-Jul;28(6):1055-7.

4. Ohgiya Y, Oka M, Hiwatashi A, Liu X, Kakimoto N, Westesson PL, Ekholm SE. Diffusion tensor MR imaging of the cervical spinal cord in patients with multiple sclerosis. Eur Radiol. 2007 Oct;17(10):2499-504.

2008

1. Sharma AK, Westesson P-L. Preoperative evaluation of spinal vascular malformation by MR angiography: How reliable is the technique Case report and review of literature. Clin Neurol Neurosurg. 2008 Mar 20. [Epub ahead of print]

2. Sharma AK, Scott G, Westesson PL. MRI sign of nodular fasciitis: a case report. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2008 May;105(5):e53-6.

3. Malhotra A, Westesson P-L. Giant intracranial aneurysm. Pediatr. Radiol 2008 [in press].

• Medical student teaching
• Resident teaching
• ED Memo Instructions
• Fellowship in neuroradiology
• Getting the most out of your Neuroradiology Rotation
  by P-L Westesson, MD, PhD, DDS
• How to Dictate and Do ICD9 Coding in Neuroradiology
  by P-L Westesson, MD, PhD, DDS
• How to read a head CT
  by Henry Z. Wang, MD, PhD
• Journal Club Evaluation Form
• Neuro ICD9 Codes
• Sample CT dictations for incoming residents
• Sample MR dictations for incoming residents
• Scanning Tips: Descreening

There is close interaction between attendings, fellows and residents in the analysis and interpretation of the MR cases here in the neuroradiology MR reading room. Both films and PACS are used for neuroradiology studies, while the rest of the department is totally filmless.

The Division of Diagnostic & Interventional Neuroradiology holds Journal Club twice a month following a schedule. The fellows and researchers each prepare an article for presentation and then each article is discussed. The quality of the articles presented are formally evaluated using this form.

Dr. Numaguchi is lecturing to the fellows with Dr. Buadu as an observant listener.

Text Books Published

Maxillofacial Imaging: An Atlas

Tore A. Larheim, DDS, PhD Professor and Head Department of Maxillofacial Radiology Institute of Clinical Dentistry University of Oslo Oslo, Norway

P-L Westesson, M.D., Ph.D., D.D.S. Professor of Radiology and Director Division of Diagnostics and Interventional Neuroradiology Department of Radiology                   and Professor of Clinical Dentistry University of Rochester School of Medicine and Dentistry Rochester, New York, USA                   and Professor of Oral Diagnostic Sciences State University of New York at Buffalo Buffalo, New York, USA                   and Associate Professor of Oral Radiology University of Lund Lund, Sweden

  Maxillofacial Imaging has evolved dramatically over the last two decades with development of new cross-sectional imaging techniques in CT and MRI. Traditional maxillofacial imaging was based on plain films and dental imaging, however, today's advanced imaging techniques with CT and MRI has only been partially implemented for maxillofacial imaging. This book bridges the gap between traditional maxillofacial imaging and advanced medical imaging. We have applied CT and MRI to large number of maxillofacial cases and these are illustrated with high-quality images in multiple-planes. This book should be useful for maxillofacial radiologists, oral and maxillofacial surgeons, dentists, radiologists, plastic surgeons, head and neck surgeons, and others that work with advanced maxillofacial cases.

New Table of Contents
Maxillofacial Imaging: An Atlas
Tore A. Larheim and P-L Westesson

MR Imaging and Spectroscopy of the
Pediatric Brain and Spine - An Atlas

Leena M. Ketonen, M.D., Ph.D.,

	Akio Hiwatashi, M.D.
	Ravinder Sidhu, M.D., and
	P-L Westesson, M.D., Ph.D., D.D.S.

   This book is a case-based pediatric neuroimaging atlas.

   The most difficult area in MR imaging is the pediatric brain and spine, and ironically there is no case atlas covering this topic specifically. We have collected typical cases of pediatric brain and spine abnormalities of outstanding quality and they will be displayed in a systematic fashion in this atlas. There will be many good quality images with a small amount of text. This atlas will be useful for radiologists, radiology residents, pediatricians, pediatric neurologists and general neurologists.

   Publication date is scheduled for November 2004.

Table of Contents

Diffusion-weighted MR Imaging of the Brain. Springer Verlag, Heidelberg, Germany. This pioneer book on diffusion-weighted MR imaging in a large variety of cases has recently been published.
   There are 15 chapters ranging from basic principles to interpretation of diffusion-weighted MR imaging and specific disease. The book will be valuable for all involved in neuroimaging, residents, fellows and staff as well as neurologists and neurosurgeons.

Diffusion-Weighted MR Imaging of the Brain

Toshio Moritani, M.D., Ph.D.,

	Sven Ekholm, M.D., Ph.D., and
	P-L Westesson, M.D., Ph.D., D.D.S.

Table of Contents

Chapter 1. Principles of diffusion-weighted imaging Chapter 2. Normal brain and artifacts Chapter 3. Brain edema - classification
- Cytotoxic edema
- Edema of neuron and glial cell
- Intramyelinic edema
- Axonal edema
- Vasogenic edemaChapter 4. Infarction
- Arterial infarction
- Venous infarctionChapter 5. Dementia
- Alzheimer’s
- Multi-infarct dementia
- Other dementias
- HIV dementiaChapter 6. HemorrhageChapter 7. Vasculitis/Vasculopathy
- Behcet
- Systemic lupus erythemyotosis
- Posterior reversal encephalopathy syndrome
- Drug induced

Chapter 8. Epilepsy
- Postictal encephalopathy
- Status epilepticus

Chapter 9. Demyelinating and degenerative disease
- ADEM
- Multiple sclerosis
- Creutzfeldt-Jakob diseaseChapter 10. Toxic and metabolic disease
Drug-induced encephalopathy
- Mitochondrial encephalopaty
- Phenylketonuria
- Osmotic myelinolysis
- Marchiafava-Bignami diseaseChapter 11. Infectious disease
- Brain abscess
- Extra-axial abscess
- Encephalitis
- Septic emboliChapter 12. Trauma
- Diffuse axonal injury
- Brain contusionChapter 13. Brain neoplasm
- Epidermoid
- Meningioma
- Lymphoma
- GBM
- Metastasis
- PNET

Chapter 14. Pediatrics
- Hypoxic ischemic encephalopathy
- Shaken baby syndrome
- Mitochondrial encephalopathy
- Multiple sclerosis
- Osmotic myelinolysis
- Herpes encephalitis

Mon

Tues

Wed

Thurs

Fri

12:00-1:00 PM
Neuroradiology
Faculty Meeting
Neuroradiology Conference
Room 1-4719

Mid-morning
Pediatric Oncology Conference
Imaging Sciences Conference Room G-3302

12:00-1:30 PM
Didactic Neuroradiology Conference based on interesting cases during the week
Neuroradiology Conference Room 1-4719

7:45 – 8:45 AM
Multidisciplinary Neuro-oncology Conference with participation from Neurosurgery, Radiation Therapy, Neuroradiology, and Neuro-Oncology
Neuroradiology Conference Room 1-4719

10:00-11:00 AM
Neuropathology/
Neurosurgery Conference
(1st Wednesday of month)
Flamingo Room
2-3615

12:00-1:00 PM
Neuroradiology Research Conference
(every other week).
Neuroradiology Conference Room
1-4719

12:00-1:00 PM
Neuroradiology Journal Club (every other week)
Neuroradiology Conference Room
1-4719

7:30-8:30 AM
Clinical Neurovascular Conference (1st Thursday)
Imaging Sciences Conference Room
G-3302

7:30-8:30 AM
Clinical Neuro-oncology Conference (2nd Thursday)
Imaging Sciences  Conference Room
G-3302

7:30-8:30 AM
Clinical Neuroscience PEDS Conference (3rd Thursday)
Imaging Sciences  Conference Room
G-3302

7:30-8:30 AM
Clinical Neuroscience Spine Conference (4th  Thursday)
Imaging Sciences  Conference Room
G-3302

7:30-8:30 AM
Clinical Neuroscience General Conference (5th  Thursday)
Imaging Sciences  Conference Room
G-3302

10:00 AM
Pathologic Clinical Correlative Conference (Brain Cutting)
Room K-1

4:00 - 5:30 PM
Head and Neck Clinical Oncology Conference (1st & 3rd Thursdays)
Flamingo Room
2-3615

8:00-9:00 AM
Multidisciplinary
Neuro-oncology Conference with participation from Neurosurgery, Radiation Therapy, Neuroradiology and Neuro-oncology
Neuroradiology Conference Room
1-4719

9:00-10:30 AM
Neurology Grand Rounds 
Room K-307

12:00-1:00 PM
Didactic Neuroradiology Conference with Video Presentation
Neuroradiology Conference Room
1-4719