Ph.D. (2003) Columbia University

Dongwen Wang, PhD Assistant Professor of Biostatistics and Computational Biology Assistant Professor of Medical Informatics Co-Director, Biomedical Informatics Program     Contact Information: University of Rochester Dept of Biostatistics and Computational Biology 601 Elmwood Avenue Box 630 Rochester, New York 14642   Office: MRBX G-11311L Phone: (585) 275-0319 Fax: (585) 273-1031 E-mail: dwang@bst.rochester.edu

Research Interests

My research interest is using informatics approach to facilitate the translation of biomedical research into clinical practice. This involves the modeling of biomedical knowledge and representation of them in computer-interpretable formats, management of biomedical data and knowledge within the context of clinical workflow, and delivery of behavioral interventions to clinicians and patients through information technology to improve healthcare processes and outcomes.

I got my PhD in biomedical informatics from Columbia University. After serving as a research faculty at Columbia for a few years, I joined University of Rochester. I was one of the developers of a computer-based guideline representation model, the GuideLine Interchange Format (GLIF), and the primary developer of the associated execution engine, the GLIF3 Guideline Execution Engine (GLEE). As a generalization of GLIF/GLEE, I developed the Guideline Execution by Semantic Decomposition of Representation (GESDOR) model. My research has been applied to address clinical problems such as improvement of immunization rate, facilitation of post-CABG critical pathway, and screening of patients with major depression. Currently, I am working on a project to develop a guideline-based clinical decision support system for management of HIV/AIDS patients.

Selected Publications

• Irigoyen M, Findley S, Wang D, Chen S, Chimkin F, Pena O, Mendonca EA (2006). Challenges of immunization registry reminders at inner city practices. Ambul Pediatr. 6(2):100-4.
• Arocha JF, Wang D, Patel VL (2005). Identifying reasoning strategies in medical decision making: a methodological guide. J Biomed Inform. 38(2):154-171.
• Wang D, Peleg M, Tu SW, Boxwala AA, Ogunyemi O, Zeng Q, Greenes RA, Patel VL, Shortliffe EH (2004). Design and implementation of the GLIF3 guideline execution engine. J Biomed Inform. 37(5):305-18.
• Boxwala AA, Peleg M, Tu S, Ogunyemi O, Zeng QT, Wang D, Patel VL, Greenes RA, Shortliffe EH (2004). GLIF3: a representation format for sharable computer-interpretable clinical practice guidelines. J Biomed Inform. 37(3):147-61.
• Wang D (2004). Translating Arden MLMs into GLIF guidelines -- a case study of hyperkalemia patient screening. Stud Health Technol Inform. 101:177-81.
• Peleg M, Boxwala AA, Tu S, Zeng Q, Ogunyemi O, Wang D, Patel VL, Greenes RA, Shortliffe EH (2004). The InterMed approach to sharable computer-interpretable guidelines: a review. J Am Med Inform Assoc. 11:1-10.
• Wang D, Peleg M, Bu D, Cantor M, Landesberg G, Lunenfeld E, Tu SW, Kaiser GE, Hripcsak G, Patel VL, Shortliffe EH (2003). GESDOR -- a generic execution model for sharing of computer-interpretable clinical practice guidelines. Proc AMIA Symp. 694-8.
• Wang D, Peleg M, Tu SW, Boxwala AA, Greenes RA, Patel VL, Shortliffe EH (2002). Representation primitives, process models and patient data in computer-interpretable clinical practice guidelines: a literature review of guideline representation models. Int J Med Inform. 68(1-3):59-70.
• Wang D, Shortliffe EH (2002). GLEE -- A model-driven execution system for computer-based implementation of clinical practice guidelines. Proc AMIA Symp. 855-9.
• Patel VL, Branch T, Wang D, Peleg M, Boxwala A (2002). Analysis of the process of encoding guidelines: a comparison of GLIF2 and GLIF3. Methods Inf Med. 41(2):105-13.
• Wang D, Peleg M, Tu SW, Shortliffe EH, Greenes RA (2001). Representation of clinical practice guidelines for computer-based implementations. Medinfo. 10:285-9.
• Wang D, Jenders RA (2000). Model-based immunization information routing. Proc AMIA Symp. 878-82.
• Wang D, Jenders RA, Dasgupta B (1999). Translating national childhood immunization guidelines to a computer-based reminder recall system within an immunization registry. Proc AMIA Symp. 994-8.