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Research Interests
Xin Tu (Ph.D.) is Professor of Biostatistics and Psychiatry in the Department of Biostatistics and Computational Biology and Department of Psychiatry. He is the Director of the Statistical Consulting Center and the Director of the Psychiatric Statistics Division within the Department of Biostatistics and Computational Biology.
Dr. Tu has done important work in the areas of U-statistics, longitudinal data analysis, survival analysis with interval censoring and truncation, and pooled testing, and has successfully applied his novel development to addressing important methodological problems in HIV/AIDS, mental health and psychosocial research. In recent years, he and his group have been focusing on issues arising in research on accuracy of proxy outcomes, causal effect from group-based psychosocial interventions and observational longitudinal data, and intervention pathways (mechanism of action) as well as interplay between biological, behavioral and societal factors in the study of disease etiology and treatment.
Dr. Tu has co-authored a book entitled: Modern Applied U-Statistics (available in December from Wiley), six book chapters, over ninety peer-reviewed publications and numerous conference abstracts. He has mentored two Ph.D., one postdoctoral and numerous Master-level students in biostatistics. The Ph.D. and postdoctoral students all have successfully secured faculty positions at major research universities including the Johns Hopkins University. He is currently mentoring two post-doctoral and three pre-doctoral students.
Selected References
- DeGruttola, V. and Tu, X.M. (1994). Modeling the relationship between disease progression and survival time. Biometrics 50:1905-1919.
- Tu, X.M., Litvak, E., and Pagano, M. (1995). On the informativeness and accuracy of pooled testing in estimating prevalence of a rare disease: application to HIV screening. Biometrika 82:287-297.
- Tu, X.M., Kowalski, J., Zhang, J., Lynch, K. and Crits-Christoph, P. (2004). Power analyses for longitudinal trials and other clustered study design. Statistics in Medicine 23: 2799-2815.
- Morrison-Beedy, D., Carey, M.P. and Tu, X.M. (2006). Accuracy of audio computer-assisted self-interviewing (ACASI) and self-administered questionnaires for the assessment of sexual behavior. AIDS and Behavior 10:541–552.
- Marcus, S.M., Gorman, J.M., Tu, X.M., Gibbons, R.D., Barlow, D.H., Woods, S.W. and Shear, M.K. (2006). Rater bias in a blinded randomized placebo-controlled psychiatric trial. Statistics in Medicine 25:2762-2770.
- Gelfand, L.A., Strunk, R., Tu, X.M., Noble, R.E.S. and DeRubeis, R. (2006). Bias resulting from using ‘assay sensitivity’ as an inclusion criterion for meta-analysis. Statistics in Medicine 25:943-955.
- Tu, X.M., Kowalski, J., Crits-Christoph, P., and Gallop, R.J. (2006). Power analyses for correlations from clustered study designs. Statistics in Medicine 25:2587-2606.
- Lamberti, J.S., Olson, D., Crilly, J.F., Olivares, T., Williams, G.C., Tu, X.M., Tang, W., Wiener, K., Dvorin, S., Dietz, M.B., Bushey, M.P. and Maharaj, K. (2006). Prevalence of the metabolic syndrome among patients receiving Clozapine. The American Journal of Psychiatry 163:1273-1276. Link to BBC World News coverage.
- Tu, X.M., Zhang, J., Kowalski, J., Shults, J., Feng, C., Sun, W. and Tan, W. (2007). Power analyses for longitudinal study designs with missing data. Statistics in Medicine 26:2958-2981.
- Lyness, J.M., Kim, J., Tang, W., Tu, X.M., Conwell, Y. King, D.A. and Caine, E.D. (2007). The clinical significance of subsyndromal depression in older primary care patients. American Journal of Geriatric Psychiatry 15:214-223.
- Tu, X.M, Feng, C., Kowalski, J., Tang, W., Wang, H., Wan, C. and Ma, Y. (2007). Correlation analysis for longitudinal data: Applications to HIV and psychosocial research. Statistics in Medicine 26:4116-4138.
- Morrison-Beedy, D., Carey, M.P., Feng, C. and Tu, X.M. Predicting sexual risk behaviors among adolescent and young women using a prospective diary method. Research in Nursing & Health (in press).
- Ma, Y., Tang, W., Feng, C. and Tu, X.M. Inference for Kappas for Longitudinal and Other Clustered Study Data: Application to HIV Prevention. Biometrics (in press).
Books
- Kowalski, J. and Tu, X.M. (December 2007). Modern Applied U-Statistics. Wiley.
- Tang, W. and Tu, X.M., Editors. Modern Clinical Trial Analysis. Springer Science (in preparation).
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