PREP Program: General Description of Laboratory Duties
University of Rochester School of Medicine
Department of Microbiology & Immunology 
PREP Faculty Research Descriptions: Organized by Scientific Interest

For a listing of faculty research, organized alphabetically, click here.

For a faculty research brochure (PDF format; readable with Abode Acrobat), click here.



Immunology

FACULTY AREA OF RESEARCH INTEREST
Barth, Richard K. Pulmonary Fibrosis, T Cell Immunity
Bottaro, Andrea Regulation of Immunoglobulin Genes
Bidlack, Jean Pharmacology of brain and lymphocytic opioid receptors
Blaxall, Burns Cytokine Regulation of Cardiac Gene Expression
Crispe, Nick Cell cycle control and apoptosis in T lymphocytes in vivo
Fowell, Deborah Genetic Determinants that Shape the Immune Response During Infectious and Autoimmune Disease
Frelinger, John G. Immunity to Tumor Antigens
Jin, Xia Immune Responses to HIV-1; HIV Vaccine Development
Li, Willis Developmental Significance of JAK/STAT Signaling Pathways
Livingstone, Alexandra T Cell Memory.
Lord, Edith M. Cell Mediated Immunity to Tumors
Maggirwar, Sanjay NFkB as a Survival Factor in Neurons and in Cancer Cells
Miller, Jim Role of LFA-1 in T Cell Costimulation
Miller-Graziano, Carol Immunobiology and Stress Response Research
Mosmann, Tim Immune Regulation by T Cell Subsets and their Cytokines
Moynihan, Jan Psychoneuroimmunology
Phipps, Richard P. B Cells and Prostaglandins; Fibroblasts as Effector Cells in Immunity.
Robert, Jacques Evolution of T Cell Immunity and Immune Surveillance
Rose, Robert Human Papillomavirus: Immunity and Vaccine Development
Sant, Andrea Class II Restricted Antigen Presentation
Sanz, Ignacio B Cells and Antibodies in Tolerance and Autoimmunity
Schwarz, Edward Molecular Mechanisms in Rheumatoid Arthritis
Segal, Benjamin Immune Responses in the Brain: Autoimmunity and Tumor Immunotherapy
Simpson-Haidaris, Patricia Role of Fibrinogen in Inflammation
Topham, David T Cell Immunity to Respiratory Viruses
Young, Fay Normal and Abnormal B-lymphocyte Development
Yule, David Mechanisms Underlying Ca2+ Signaling Events




Microbiology and Microbial Pathogenesis

FACULTY AREA OF RESEARCH INTEREST
Butler, Scott Post-transcriptional Regulation of mRNA Expression in the Nucleus of Eukaryotic Cells
Clark, Virginia Regulation of Virulence in Neisseria gonorrhoeae
Dumont, Mark Yeast Molecular Biology, Signal Transduction
Haidaris, Constantine Pathogenesis of Infectious Eukaryotic Microorganisms
Hayes,Jeffrey DNA Structure, Protein-DNA Interactions Includes new work using a slime mold model system.
Marquis, Robert E. Microbial Physiology
Miller, Benjamin Biomolecular Sensing for Detection of Microbial Pathogens
Pavelka, Martin Biosynthesis of the Cell Wall of Mycobacterium tuberculosis
Pearce, David Yeast Models for Human Disease
Phizicky, Eric Functional Genomics, tRNA Processing in Yeast
Quivey, Robert Regulation of Bacterial Gene Expression
Turner, Doug RNA Structure, Therapeutics
Includes studies targeting human pathogens such as Pseudomonas aeruginosa and Candida albicans.




Tumor Immunology and Tumor Virology

FACULTY AREA OF RESEARCH INTEREST
Barth, Richard K. Pulmonary Fibrosis in Cancer
Crispe, Nick Cell Cycle Control and Apoptosis in T Lymphocytes
Dewhurst, Stephen Viral Vectors and Breast Cancer Vaccine Development.
Frelinger, John G. Immunity to Tumor Antigens
Lord, Edith M. Cell Mediated Immunity to Tumors
Maggirwar, Sanjay NFkB as a Survival Factor in Cancer Cells and in Neurons
Phipps, Richard P. Prostaglandins as Anti-Tumor Agents; Pulmonary Fibrosis in Cancer.
Rose, Robert Human Papillomavirus: Immunity and Vaccine Development
Segal, Benjamin Tumor Immunotherapy in the Brain
Simpson-Haidaris, Patricia Role of Fibrinogen in the Extracellular Matrix in Cancer
Young, Fay Development of B Cell Tumors


Vaccine Biology

FACULTY AREA OF RESEARCH INTEREST
Bowers, Bill Development of HSV amplicon-based gene therapy for treatment of neurodegenerative diseases.
Dewhurst, Stephen Viral Vectors and Vaccine Development for HIV and Breast Cancer.
Jin, Xia Immune Responses to HIV; HIV Vaccine Development.
Rose, Robert Human Papillomavirus: Immunity and Vaccine Development




Virology

FACULTY AREA OF RESEARCH INTEREST
Bambara, Robert HIV Reverse Transcriptase
Bowers, Bill Development of HSV amplicon-based gene therapy for treatment of neurodegenerative diseases.
Demeter, Lisa HIV-1 Drug Resistance and Recombination
Dewhurst, Stephen Viral Vectors and HIV/Cancer Vaccine Development; Mechanisms of NeuroAIDS; Human Herpesvirus-7.
Gelbard, Harris Effects of HIV-1 Infection on Neuronal Function, Signaling, and Fate in the CNS
Jin, Xia Immune Responses to HIV; HIV Vaccine Development.
Kim, Baek HIV Reverse Transcripase: Fidelity and Role in Evolution; HIV Protease
Maggirwar, Sanjay Role of NFkB in Neuronal Survival in AIDS
Rose, Robert Human Papillomavirus: Immunity and Vaccine Development
Smith, Harold Functional Analysis of an HIV-Inhibitory RNA Editing Enzyme, CEM15.
A separate project-specific web page is also available, and a recent news article describes a related biotech company that has been generated by Dr. Smith.
Takimoto, Toru Molecular Mechanisms of Paramyxovirus Infection, Replication and Assembly
Ward, Brian Molecular Mechanisms of Poxvirus Envelope Formation
Wedekind, Joseph Structural Analysis of an HIV-Inhibitory RNA Editing Enzyme, CEM15.
A separate project-specific web page is also available.