University of Rochester School of Medicine
Department of Microbiology & Immunology 
MBI 456: General Virology Course

MBI 456 General Virology

Spring – 2007
Monday, Wednesday, Friday
10:00 – 10:50
Room Assignment
K307 (3-6408), Whipple Aud (2-6424), Upper Aud (3-7619)
Class of 62 Aud (G-9425: 2/9/07 only)
Course Director:
Baek Kim
Date Room Lecture Instructor
January 17 (Wed) K307 Introduction to Viruses
(handout) (presentation)
SD
19 Upper Aud Virus Entry
(handout) (presentation)
SM
22 (Mon) K307 Replication Strategies
(handout) (presentation)
SM
24 K307 Viral Structure and Assembly
(handout) (presentation)
RR
26 Whipple Aud Techniques for Studying Viruses – Assay Methods
(presentation)
SM
29 (Mon) K307 DNA Viruses- Poxvirus I
(presentation)
BW
31 K307 DNA Viruses- Poxvirus II
(presentation)
BW
February 2 Whipple Aud DNA Viruses – SV40/Polyoma:
(handout) (presentation)
RR
5 (Mon) K307 DNA Viruses – Papillomaviruses
(handout) (presentation)
RR
7 K307 DNA Viruses –
Herpesviruses I (HSV-1)
(handout) (presentation)
SD
9 Class of 62 Aud DNA Viruses –
Herpesviruses II (EBV)
(handout) (presentation)
SD
12 (Mon) K307 DNA Viruses –
Herpesviruses III (HHV-8)
(handout) (presentation)
SD
14 Review of Exam 1 SD, SM, RR, BW, BK
16 Whipple Aud Exam 1 (12 lectures): 2 hours
- 30% of final grade
 
19 (Mon) K307 Paramyxovirus I
(handout) (presentation)
TT
21 K307 Paramyxovirus II
(handout) (presentation)
TT
23 Whipple Aud Influenza virus I
(handout) (presentation)
TT
26 (Mon) K307 Influenza virus II
(handout) (presentation)
TT
28 Whipple Aud Yellow fever/Dengue viruses
(handout) (presentation)
RR
March 2 Whipple Aud Hepatitis Viruses I : HCV
(handout) (presentation)
RR
5 (Mon) K307 Hepatitis Viruses II: HBV
(handout) (presentation)
RR
7 K307 Retroviruses – Introduction and Oncoretroviruses
(presentation)
BK
9 Whipple Aud Retroviruses – Viral Replication and Reverse Transcription
(presentation)
BK
12 (Mon)   Spring Break  
14   Spring Break  
16   Spring Break  
19 (Mon)   No Class  
21 K307 Retroviruses –Retroviral Enzymes
(presentation)
BK
23 Whipple Aud Retroviruses –Antiviral reagents, Drug resistance, and Host factors
(presentation)
BK
26 (Mon) K307 HIV I
(presentation)
XJ
28 K307 HIV II
(presentation)
XJ
30 Whipple Aud HIV III
(presentation)
XJ
April 2 (Mon) K307 Review for Exam 2 TT, XJ,RR, BK
4 Whipple Aud Exam 2 (14 lectures): 2 hours
- 30% of final grade
 
6 Whipple Aud Viral Immunology – I
(presentation) (handout)
DT
9 (Mon) K307 Viral Immunology – II
(presentation) (handout)
DT
11 K307 Viral Immunology – III
(handout)
DT
13 Whipple Aud Viral Vectors and
Gene Therapy –I
(presentation)
WB
16 (Mon) K307 Viral Vectors and
Gene Therapy –II
(presentation)
WB
18 K307 Viral Vectors and
Gene Therapy –III
(presentation)
WB
20 Whipple Aud Viral Vectors and
Gene Therapy –IV
(presentation)
WB
23 (Mon) K307 Viral Vaccines I:
(presentation) (handout)
RR
25 K307 Viral Vaccines II:
(presentation) (handout)
RR
27 Whipple Aud Emerging Viruses
(presentation) (handout)
RR
30 (Mon) K307 Responsible Virology Research/Bio-defense
(presentation)
BW
May 2 K307 Review of lectures from entire course
(Last day of class)
All lecturers
11 Whipple Aud Final Exam: 3 hours

– 40% of final grade (20% for last 11 lectures and 20% for cumulative lectures)

 

Instructors

Name Email Tel
Bowers, William (WB) william_bowers@urmc.rochester.edu 273-2195
Dewhurst, Steve (SD) stephen_dewhurst@urmc.rochester.edu 275-3216
Jin, Xia (XJ) xia_jin@urmc.rochester.edu 375-5871
Kim, Baek (BK) baek_kim@urmc.rochester.edu 275-6916
Maggirwar, Sanjay (SM) Sanjay_Maggirwar@urmc.rochester.edu 273-2276
Rose, Robert (RR) robert_rose@urmc.rochester.edu 275-0263
Takimoto, Toru (TT) toru_takimoto@urmc.rochester.edu 273-2856
Topham, David (DT) david_topham@urmc.rochester.edu 275-9297
Brian Ward (BW) Brian_ward@urmc.rochester.edu 275-9715

Teaching Assistant: Handouts

Cristina Capella
Email: cristina_capella@urmc.rochester.edu
Phone: x5-2708
Office hour
: TBA 
Sara Johnston
Email: sara_johnston@urmc.rochester.edu
Phone: x5-5334
Office hour: Tuesday and Thursday, 3:00~4:00pm

Recommended Textbook

Viruses and Human Diseases
Authors: James H. Strauss and Ellen G. Strauss
This textbook is available at the Medical Center Bookstore (and any web book sellers).

Supplementary Textbooks

Fields Virology: (Vol.1&2)
by Bernard N. Fields (Editor), David M. Knipe (Editor), Peter M. Howley
Hardcover 4th edition (2001)
Lippincott Williams & Wilkins Publishers; ISBN: 0781718325; Bk&Cd-Rom edition (August 2001)
Principles of Virology: Molecular Biology, Pathogenesis, and Control
Author(s)/Editor(s): S.J. Flint, L.W. Enquist, R.M. Krug, V.R. Racaniello, and A.M. Skalka
ASM Press, December 2003