
Publications
Below is a full listing of all publications of our research group.
*Click on any citation to go to the associated PubMed page
- Jamburuthugoda VK, Chugh P, Kim B Modification of human immunodeficiency virus type 1 reverse transcriptase to target cells with elevated cellular dntp concentrations. J Biol Chem. 2006 Feb 22; [Epub ahead of print]
- Purohit V, Balakrishnan M, Kim B, Bambara RA (2005, in press) Evidence that HIV-1 reverse transcriptase employs the DNA 3' end-directed primary/secondary RNase H cleavage mechanism during synthesis and strand transfer. J Biol Chem 280(49): 40534-43.
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Jamburuthugoda VK, Guo D, Wedekind JE, and Kim B (2005) Kinetic Evidence for Interaction of Human Immunodeficiency Virus Type 1 Reverse Transcriptase with the 3'-OH of the Incoming dTTP Substrate. Biochemistry 44(31):10635-43
- Operario DJ, Reynolds HM, and Kim B (2005). Enzymatic Comparison of DNA polymerase activities of Feline Immunodeficiency Virus and Feline Leukemia Virus. Virology. 335(1):106-21.
- Skasko M, Weiss KK, Reynolds HM, Jamburuthugoda V, Lee K, and Kim B (2005) Mechanistic Differences in RNA dependent DNA polymerization and Fidelity between MuLV and HIV-1 Reverse Transcriptases. J. Biol. Chem. 280(13):12190-200.
- Dehart JL, Andersen JL, Zimmerman ES, Ardon O, An DS, Blackett J, Baek Kim, Planelles V. (2005) The ataxia telangiectasia-mutated and Rad3-related protein is dispensable for retroviral integration. J. Virol. 2005 79(3):1389-96.
- Weiss, K. K., Chen, R., Skasko, M., Reynolds, H. M., Lee, K., Bambara, R. A., Mansky, L. M., and Kim, B. (2004) A Role for dNTP Binding of Human Immunodeficiency Virus Type 1 Reverse Transcriptase in Viral Mutagenesis,Biochemistry 43, 4490-4500.
- Roshal, M., Kim, B., Zhu, Y., Nghiem, P., and Planelles, V. (2003) Activation of the ATR-mediated DNA damage response by the HIV-1 viral protein R,J Biol Chem 278, 25879-86.
- Diamond, T. L., Souroullas, G., Weiss, K. K., Lee, K. Y., Bambara, R. A., Dewhurst, S., and Kim, B. (2003) Mechanistic understanding of an altered fidelity simian immunodeficiency virus reverse transcriptase mutation, V148I, identified in a pig-tailed macaque,J Biol Chem 278, 29913-24.
- Weiss, K. K., Bambara, R. A., and Kim, B. (2002) Mechanistic role of residue Gln151 in error prone DNA synthesis by human immunodeficiency virus type 1 (HIV-1) reverse transcriptase (RT). Pre-steady state kinetic study of the Q151N HIV-1 RT mutant with increased fidelity,J Biol Chem 277, 22662-9.
- Malboeuf, C. M., Isaacs, S. J., Tran, N. H., and Kim, B. (2001) Thermal effects on reverse transcription: improvement of accuracy and processivity in cDNA synthesis,Biotechniques 30, 1074-8, 1080, 1082, passim.
- Diamond, T. L., Kimata, J., and Kim, B. (2001) Identification of a simian immunodeficiency virus reverse transcriptase variant with enhanced replicational fidelity in the late stage of viral infection,J Biol Chem 276, 23624-31.
- Weiss, K. K., Isaacs, S. J., Tran, N. H., Adman, E. T., and Kim, B. (2000) Molecular architecture of the mutagenic active site of human immunodeficiency virus type 1 reverse transcriptase: roles of the beta 8-alpha E loop in fidelity, processivity, and substrate interactions,Biochemistry 39, 10684-94.
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