ANA 513. Neuroinflammation

Assoc. Professors Olschowka & O'Bannion, and Res. Asst. Professor Hurley

Pre-requisite: NSC 512 and MBI 473/573 (Immunology) are recommended

Credit: four hours

Inflammation contributes to secondary injury following brain trauma or stroke, and is often a direct cause of neuropathology in the nervous system. And yet, neuro-inflammation may also be critical for regeneration and repair. This course will examine the role of inflammation in the central nervous system, and will highlight common mechanisms of response to a variety of neural insults, including autoimmunity, trauma, neuro-toxicology, and neuro-degeneration. Further topics will include the roles glia, the acquired immune system, and the innate immune system play in response to neural insults in the unique "immune-privileged" environment of the CNS. (spring of even years)