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Principal Investigator: Anne Luebke, Ph.D.Associate Professor:
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Laboratory Overview
The long-term goal of my laboratory is to understand the role of cochlear
outer hair cells in hearing and hearing loss both at the molecular and at
the systems level. Specifically, we are interested in agents that block or
enhance the action of receptors on outer hair cells of the cochlea, which
enhance hearing and decrease hearing loss. To design and discover agents that
block or enhance receptor action on cochlear outer hair cells, we are cloning
neurotransmitter receptors expressed in the hair cells, and modulating expression
of these receptors by viral-mediated gene transfer into the cochlea.