The University of Rochester Sleep & Neurophysiology Research Laboratory is located on the basement level of the Psychiatry Department. The lab includes a hotel-like suite, four offices, a conference room, a physical exam room, and an ERP/Psychophysiology chamber. The suite includes four bedrooms, two full baths, a control room, a kitchenette, living/dining room and a laundry room. Two of the bedrooms are RF shielded and two of the bedrooms have sound insulated catheter portals (for studies that require blood sampling or for the infusion of radiopharmaceuticals for imaging studies). The control room contains the electrophysiologic equipment, four computers dedicated to acquisition of PSG data, two computers dedicated to off-line data processing (sleep scoring, PSA, and Statistical Analysis) and a one terabit data server that is utilized in the collection of data as well as containing a substantial archive of articles and reference material. In addition to the computers the control room also contains DVD based recording equipment linked to our therapy rooms. The bedrooms are connected via intercoms to the control room and the bedrooms can be monitored via infrared video. The laboratory can also implement cognitive neuroscience and medical protocols. In addition to routine polysomnographic assessment, the lab is set up to acquire a broad range of electrophysiologic signals (i.e., EEG, EMG, EOG, EKG, EGG, GSR) and to undertake a variety of signal-processing techniques (e.g., PSA, DPA, ERPs). The location within the medical center provides easy access to medical personnel, biomedical engineering, clinical laboratories (e.g., Human Clinical Chemistries Laboratory) and other research laboratories (e.g., Neuroimaging Laboratory, Psychoneuroendocrine Laboratory, etc.)