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Aryloxypropanoic Acids-Based Mitochondrially Targeted Prodrugs. I. Phenol and Pyridinol-Based Antioxidants
With 6-1250 and 6-1467, this suite of technologies describes therapeutic approaches to diseases such as neurodegeneration, stroke, ischemia/reperfusion, diabetes, cardiomyopathy, and cancer that involved targeting the mitochondria. More specifically, these technologies describe the synthesis of mitochondrial targeted antioxidant compounds that will reduce ROS production and damage which underlies or contributes to the progression of disease.
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Matan Rapoport, Ph.D.
Office of Technology Transfer
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