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Prognostic Indicator of HIV/AIDS: CEM15 mRNA Levels
Technology ID:
6-1375
Applications:
Present invention provides a method of measuring a novel prognostic marker for AIDS progression, and predicting whether a viral infected patient will be a nonprogressor. This invention also provides a method of predicting the level of CD4 cells in a patient, as well as a method of optimizing antiviral therapy in a viral infected patient.
Advantages:
A small subset of the AIDS patients categorized as long term nonprogressors (LTNPs) have a much slower disease progression rate. Several mechanisms have been suggested for LTNPs. However, no common factor has been identified to correlates LTNPs. The present invention provides a method of measuring one novel marker to predict AIDS progression in a patient and predict whether the patient will be LTNP. This invention also provides insights into novel therapeutic targets discovery for AIDS treatment. This invention has significant implications on new development of diagnostic tools and therapeutic targets to treat viral infections.
Intellectual Property Status:
U.S. Patent Application Number 11/816,063 filed on 08/10/2007
Additional international patent(s) pending
Additional international patent(s) pending
Inventors:
For Additional Information or for Licensing Opportunities:
Michael Rusnak
Associate Director
Office of Technology Transfer
585.784.8850
Associate Director
Office of Technology Transfer
585.784.8850
Category:
Diagnostic:Infectious Diseases
Keywords:
AIDS, Diagnostic, HIV, RNA
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