Entrepreneur-Ready Technologies has been introduced to help highlight some of the University of Rochester’s most promising inventions. We believe the technologies and innovations described below have significant commercial potential. Some of these items could fit nicely into a company’s existing intellectual property portfolio to enhance a product line or help launch a new one. Others represent platform technologies that could constitute the foundation of a new startup company. In either case, we invite you to peruse the following which will be updated periodically with new featured patents. If anything is of interest, please contact the Office of Technology Transfer.
A New Class of Antifungal Agents
This invention identifies and validates a novel and effective way to treat fungal infections.
A Novel Method to Predict the Outcome of Chronic Lymphocytic Leukemia
This invention provides a simple and robust in vitro DNA-based diagnostic assay to aid in determining the prognosis of patients with chronic lymphocytic leukemia.
Treatment for Brain Impairment Caused by Herperammonemia
Compounds that inhibit NKCC1 activity directly target hyperammonemia-induced brain impairment and thus have fewer side effects than the existing treatments.
A Therapeutic Approach to Replace or Improve Deep Brain Stimulation
This invention provides an approach to achieve the beneficial effects of DBS at lower stimulation intensities or without surgical intervention.
Inducing Immune Responses Using Platelets
Platelets are useful vehicles to induce immune responses. This will be beneficial as a novel form of vaccination or as a means to augment traditional vaccine responses.
A Novel Method for the Treatment of Psoriasis
A novel pathway inhibitor for the treatment of psoriasis.
Photoactivatable Chemokine Receptors
Light-sensitive polypeptide to aid with directional cell migration during numerous physiological processes including tissue morphogenesis, inflammation, immune responsiveness, wound healing, and regulation of cell growth and differentiation.
Integrated Multi-Criteria Decision Support Framework
A medical decision dashboard that provides patients with a recommended treatment option based on patient-ranked criteria.
Deep Brain Magnetic Stimulator
A new medical device that uses transcranial magnetic stimulation (TMS) to deliver electrical pulses to treat specific areas of the brain. The device is implanted deep within the brain and is capable of targeting small and specific regions for treatment.
New Recombinant Activated Protein C
A new method to treat sepsis, a major cause of death in intensive-care units, by binding to neutrophil integrins at high affinity at sites of infections and reducing the neutrophil migration during sepsis.
Biopsy Device for Lumpectomy Excisions
Optical inspection system to assist a pathologist in determining if an excised specimen includes the complete lesion.
Download two-page technology summary
Video Game for Increased Math Skill
An action-packed video game developed to train mathematics skills in non-verbal number sense and by following established factors for brain plasticity and learning.
Shape Memory Polymers
Shape memory polymers with the unique property of a tunable shape recovery rate. This allows bulky synthesized objects to be deformed into smaller, pliable states and then returned at a controlled rate to the original shape.
Devices and Method for Improved Diagnosis of GERD-Related Respiratory Disease
Measurements of simultaneous continuous pulse oximetry and esophageal pH monitoring to serve as an improved diagnostic test for patients with respiratory disease associated with gastroesophageal reflux.
Robust Array-Capable Optical Biosensor
Bio-molecules are detected by the change in reflectivity of polarized light from a micro-array silicon chip surface, for measurement of biomolecular interaction rates and the detection of pathogens.
Highly Fluorescent Near-IR Quantum Dots
These semiconductor nano-clusters are highly fluorescent in the near infra red, of extremely small diameter (< 2 nm), and easily fabricated.
High Molecular Weight Hyaluronic Acid
A source of and methof for creating high molecular weight hyaluronic acid.
Video Game Treatment for Lazy Eye
An action video game with a split screen or head-mounted display is used to treat “lazy eye” (amblyopia). The game is fun and can be played at home.
Featured in ScienceDaily.
Membrane for Intermediate Temperature Fuel Cells
Thin, dense composite membranes of c-axis aligned hydroxyapatite single crystals. The gas-tight and proton-conducting membranes enable fuel cells to operate in the 300 - 600 degrees Celsius range.
An instrument for real-time determination of photodynamic therapy dosimetry in vivo, employing measurements of fluorescence emission spectra corrected for effects of dynamic tissue optical properties using white light diffuse reflectance.
Ultrasound Measurement of Tissue Stiffness
This method provides a non-invasive measurement of tissue stiffness unavailable in traditional ultrasound images for the diagnosis of diseases.
Audio Data Hiding
Enables the insertion and recovery of hidden data in audio files through manipulation of the relative phase of harmonically related components of a host audio signal.
Color Image Bar Code
This color image encoding and data extraction technique provides the equivalent of a high data capacity 2D bar code in a tone-adjusted image for a more attractive printed data element.
Low Noise Infra-Red Detector
A novel semiconductor structure comprising of a unipolar barrier layer inserted to block unwanted surface current, but pass bulk current, in IR detector arrays and other devices.
Targeting, Silencing, or Modifying RNA Transcripts
Allows for the creation of molecules that can selectively target RNA molecules that benefit from modifications to splice sites to make them perform in a proper function.
Mesenchymal Stem Cell Populations to Treat Bone Disorders
Stem cell technologies that work synergistically to treat orthopaedic diseases and injuries, such as trauma, spinal fusion, tissue engineering, and bone defects.
Ultra-High Resolution Ophthalmoscope
A microscope for viewing the retina at the back of the eye at the cellular level to detect disease at a very early stage before blindness occurs.
Optical Detection of Nano-Particles
Particles as small as 5 nanometers are detected optically in a nanoscale channel in a micro-fluidic system.
Hybridization-Based Unquenching of DNA Hairpins on Au Surfaces
Identifies the use of olignucleitide sequences, which consist of natural genes and contain a number of bases, making the technique more arrayable and practical.
Titanium Aluminide Metal Forming
Manufacturing method for high temperature, wear-resistant components of intermetallics, such as TiAl, for engine valves and other uses.
Documents and Forms
Sample License and Option Agreements
Sample Exclusive License Agreement.
Sample Nonexclusive License Agreement.
Sample Option Agreement.
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