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UCAR Manual on the Responsible Care and Use of Laboratory Animals

Institution Animal Care and Use Committee (IACUC)

The Institutional Animal Care and Use Committee (I.A.C.U.C.) is required by federal law and as a condition of N.I.H. funding. The University of Rochester I.A.C.U.C. Is the University Committee on Animal Resources (U.C.A.R.). The U.C.A.R. must have at least five members, including a veterinarian with program responsibilities, a scientist experienced in laboratory animal research, a non-scientist and an individual who has no affiliation with the institution besides U.C.A.R. membership. The following U.C.A.R. functions are mandated by the U.S.D.A. through the Animal Welfare Act regulations or required by the Public Health Service as a condition of NIH funding.

  1. U.C.A.R. reviews proposed research protocols for compliance with USDA Regulations and P.H.S. Policy and guidelines. The principal investigator submits the "Authorization to Use Animals in Research or Testing" form to the U.C.A.R. Please refer "Forms" in the sidebar for a copy of the current form. The guidelines for U.C.A.R. can be accessed in "Extended Help for New Forms" also located in the sidebar. The U.C.A.R. may approve or require more information or modifications before approval. All animal research and testing protocols must be prospectively reviewed and approved by the U.C.A.R.
  2. U.C.A.R. Reviews all approved protocols annually. The U.C.A.R. secretary sends the U.C.A.R. Annual Protocol Review to the principal investigator for completion before the anniversary date of the approval. All protocols must be reviewed and approved annually. Full protocol review occurs every three years. Any protocol modification must be prospectively approved.
  3. U.C.A.R. Must inspect, at least once every six months, all of the animal facilities, including animal study areas/satellite facilities , using the USDA Regulations and P.H.S. Guide as basis. U.C.A.R. submits a written report of the inspection to the Institutional Official. The Institutional Official (Dr. Bradford Berk) is the individual at a research facility who is authorized to legally commit on behalf of the research facility that the requirements of the federal regulations are met. U.C.A.R. suspends an activity involving animals when necessary; takes corrective action and reports to the funding agency and/or USDA.
  4. U.C.A.R. makes recommendations to the Institutional Official regarding any aspect of the research facility's animal program, facilities or personnel training.
Please contact the U.C.A.R. Secretary at X 5-1693 to schedule a meeting for assistance or more information.