URMC Labs - Department of Pathology & Laboratory Medicine

Bone and Muscle Pathology

Department Investigators

Brendan F. Boyce Osteoclast & osteoblast pathophysiology, preclinical models
Lianping Xing Osteoclast pathophysiology in arthritis
Robert A. Mooney Obestity/type2 diabetes & bone pathology
Ping Tang Bone metastasis of breast cancer
Zhenqiang Yao Bone cell regulation

Current Awards

Brendan F. Boyce Studies of the fate of the osteoclast (NIH)
Lianping Xing Role of TNF alpha in osteoclast-mediated bone loss (NIH)
Robert A. Mooney Diabetes and S. aureus oseomyelitis (AO Trauma)
Ping Tang Predicting bone metastasis of breast cancer (NYS)

Interdepartmental Collaborations


Laura Calvi Hematopoietic-osteoblastic interactions

Orthopaedics (Center for Musculoskeletal Research)

Matthew Hilton Genetic mechanisms of skeletal development
Regis O'Keefe Clinical and basic research in osteoporosis, fracture
J. Edward Puzas Regulation of osteoclast activity
Randall Rosier Translating molecular signal pathways to orthopaedic trauma care
Eddie Schwarz Preclinical models of arthritis
Michael Zusick Chondrocytes and mechanisms of osteoarthritis

Rush University Medical Center

Di Chen Canonical Wnt signaling and mesenchymal stem cell differentiation

Educational Opportunities

  • Center for Musculoskeletal Research faculty are thesis advisors for several students in our Pathology Ph.D. program
  • Drs. Boyce, Mooney and Xing participate in the Orthopaedics training grant (T32)
  • Orthopaedic case review conference

Clinical Highlights

  • Bone and muscle pathologists: Brendan Boyce, David Hicks, Xi Wang
  • Subspecialized bone histology lab for bone and soft tissue histopathology
  • Extensive immunohistochemistry panel
  • Full menu of clinical chemistry assays including bone disease related markers: P1NP; CTX; Urinary NTX; Intact PTH; 1, 25 dihydroxy vitamin D by tandem MS

URMC Labs Test Index

A | B | C | D | E | F | G
H | I | J | K | L | M | N
O | P | Q | R | S | T | U
V | W | X | Y | Z

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