URMC Labs - Department of Pathology & Laboratory Medicine

Hematopathology

Department Investigators

John M. Bennett Hematologic neoplasms
Richard Burack Molecular mechanisms of lymphoma progression
Archibald Perkins Leukemogenesis
Janice M. Spence Lymphomagenesis
Yi Zhang Cancer molecular biology

Current Awards

Archibald Perkins Development of a polyamide-based targeted therapy for leukemia stem cell (NYS)
Archibald Perkins Mechanism of EVI1-induced leukemogenesis (NIH)
Archibald Perkins Study of a novel genetic regulator of stress hematopoiesis (Defense Dept)
Yi Zhang Targeting MDS-EVI1 complex in regulation of hematopoietic stem cells stress response (NYS)

Interdepartmental Collaborations

Wilmot Cancer Center

Richard Fisher SPORE in lymphoma
Jonathan Friedberg Southwest Oncology Group (SWOG)

Educational Opportunities

  • Postresidency fellowship in hematopathology
  • Ph.D. program thesis opportunities in cancer biology; genetics and stem cell biology; immunology, microbiology, and hematology
  • Case review conferences: Lymphoma conference, Myeloid conference, Cytogenetics/molecular/hematopathology correlation, Pediatric hematology/oncology

Clinical Highlights

  • Hematopathologists: John Bennett, Richard Burack, Archibald Perkins, Daniel Ryan
  • Bone Marrow/Hematopoietic stem cell transplantation: Laurie Milner
  • Wide variety of flow cytometry assays
  • Assays that focus on the diagnosis of leukemia and lymphoma and testing for CD34+ stem cells, lymphocyte subsets, immunodeficiency and paroxysmal nocturnal hemoglobinura.

Other Resources

  • Banked tissue specimens: Sylvie Honnons, Jorge Yao

URMC Labs Test Index

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