At the University of Rochester Medical Center, we support collaborative efforts that create bridges between researchers and clinical specialists. Our faculty participate in interdepartmental and multidisciplinary research projects. Many of them are involved in clinical laboratory testing, clinical trials testing and basic scientific research. Our goals are to use new information from the research laboratory in order to enhance clinical testing; to use knowledge gained in the examination of clinical specimens in order to develop new hypotheses for basic research; and to share our knowledge through effective educational programs.
Investigators within the Department of Pathology and Laboratory Medicine are active in basic, translational and clinical research. They are exploring the cellular and molecular pathology of bladder, prostate and breast cancer, blood group antigens, bone diseases, diabetes, hematopoiesis, immune disorders, lipid metabolism, kidney diseases, lymphomas and leukemias, neurodegenerative diseases and cardiovascular disease. Current clinical trials involve coagulation therapies.
Research facilities include equipment for confocal and electron microscopy, flow cytometry and cell analysis, immunohistochemistry, microarray construction, laser microdissection and morphometric and image analysis.
- Blumberg Laboratory (blood transfusion immunobiology)
- Boyce Laboratory (osteoclasts)
- Burack Laboratory (lymphoma)
- Chang Laboratory (androgen receptor)
- Coppage Laboratory (bone marrow niche in hematological malignancies)
- Corsetti Laboratory (atherosclerosis)
- Czyzyk Laboratory (autoantibodies and diabetes)
- Iqbal Laboratory (microarray CGH)
- Johnson Laboratory (leptomeninges and meningioma)
- Li Laboratory (molecular signaling and epigenetics in cardiovascular diseases and cancer)
- Mooney Laboratory (obesity and osteoarthritis)
- Perkins/Zhang Laboratory (oncoproteins in leukemia)
- Refaai Laboratory (ABO antibodies and platelet function)
- Sparks Laboratory (lipoproteins)
- Tang Laboratory
- Xing Laboratory (cell function in inflammatory bone loss)