Module VI - A Review of Calcium Channel Blocker Toxicity

Wednesday October 21, 1998 - Question 12

Which of the following statements about glucagon administration following calcium channel blocker ingestion is correct?

A. Glucagon is a polypeptide hormone that causes vasoconstriction without directly affecting alpha-1 receptors.

B. Glucagon decreases cyclic AMP concentrations through a receptor distinct from that of catecholamines

C. Initial doses of glucagon, ranging from 50 to 150 mcg/kg, can be administered over 1 minute.

D. The onset of glucagon’s effects is within 30 minutes of administration and will persist for 60 to 90 minutes.

E. Rather than administration by continuous infusion, intermittent intravenous doses of glucagon should be administered in the diluent provided by the manufacturer.
 
 

Discussion