Monday October 12, 1998 - Question 3

Which of the following statements about the pharmacology/toxicology of calcium and the calcium channel blockers is correct?

A. Firing at the sinoatrial and the atrioventricular nodes is dependent on the rapid influx of calcium.

B. The dihydropyridines, such as nifedipine, produce reflex decreases in heart rate.

C. Calcium channel blockade decreases impulse conduction at the sinoatrial and atrioventricular nodes.

D. In the unstressed aerobic state, the myocardium relies primarily on carbohydrates for mechanical energy.

E. During calcium channel blocker induced shock, the myocardium shifts substrate preference and relies on free fatty acids for energy.
 
 

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