Saturday October 17, 1998 - Question 8

Which of the following statements about the clinical manifestations of the calcium channel blockers is correct?

A. Contraction of vascular smooth muscle is mediated by calcium.

B. Canine studies demonstrate that nifedipine primarily causes hypotension by decreasing cardiac output.

C. In toxicity, the most common cardiovascular effects of nifedipine are hypotension and bradycardia.

D. Nifedipine has not been shown to cause conduction disturbances or have negative inotropic effects.

E. The calcium channel blockers are not known to cause non-cardiogenic pulmonary edema.
 
 

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