Monday September 14, 1998 - Question 3

Which of the following statements regarding inherited effects on drug metabolism is true?

A. Poor (slow) metabolizers are unable to metabolize most drugs.
B. Extensive (rapid) metabolizers can metabolize all drugs at a faster rate.
C. Extensive metabolizers are relatively resistant to enzyme inhibition.
D. Genetic polymorphism refers to inherited differences in drug metabolism.
E. Induction of enzymes in poor metabolizers will increase their metabolic capacity to near normal..

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