Discussion
Saturday August 15, 1998 - Question 1
Which of the following statements concerning the calcium channel blocker mibefradil (Posicor) is correct?
A) In June of 1998, the FDA imposed a mandatory
withdrawal of mibefradil from the market.
B) Mibefradil was withdrawn from the market because
it was ineffective in treating hypertension and chronic angina pectoris.
C) Mibefradil was withdrawn from the market because
of serious and potentially life-threatening drug interactions.
D) Data from a three-year long-term study of
mibefradil in CHF patients demonstrated superior efficacy over placebo
when added to standard therapy for CHF.
E) Mibefradil showed promise because it offered
unique benefits over existing agents.