Saturday August 29, 1998 - Question 1

Which of the following is correct regarding ethylene glycol poisoning?

A. The metabolic conversion of glycoaldehyde to glycolate is a slow process that can take up to 24 hours.
 
B. The metabolic conversion of glycolate to glyoxylate is rapid and occurs within 2 to 3 hours of exposure.
 
C. Glycolate is primarily responsible for the metabolic acidosis observed in ethylene glycol poisoning.
 
D. Hemodialysis is not known to enhance the clearance of glycolate.
 
E. Glyoxylate and formate significantly contribute to the toxicities seen following ethylene glycol poisoning.
 
 

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