Sunday August 30, 1998 - Question 2

Which of the following is correct regarding the pharmacokinetics of ethylene glycol?

A. Absorption of ethylene glycol is slow with a resultant delay in onset of toxicity.
 
B. Ethylene glycol is not known to be absorbed by any route other than oral ingestion.
 
C.  Ethylene glycol has a large volume of distribution of approximately 6 L/kg.
 
D. Approximately 50% of ethylene glycol is excreted unchanged in the urine.
 
E. Glycoaldehyde, glycolate, glyoxylate, oxalate, glycine and formate are known metabolites of ethylene glycol..

.
 

Discussion