Friday September 4, 1998 - Question 7

Which of the following is correct regarding fomepizole?

A. Fomepizole has the potential to increase the clearance of some medications through induction of cytochrome P-450 enzymes.
 
B. Elimination of fomepizole does not become saturated at therapeutic blood concentrations.
 
C. Therapeutic fomepizole blood concentrations are unknown.
 
D. Co-administration of fomepizole and ethanol is recommended to enhance outcomes in ethylene glycol poisoned patients.
 
E. Fomepizole blood concentrations should be monitored every 4 hours during fomepizole therapy.
 
 
 

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