Module XIV - Pharmaceutical Calculations and Interpretation of Clinical Laboratory Values

Thursday February 18, 1998 - Question 13

A 64 year-old female who weighs 142 pounds presents to the ED after ingesting 30 Lanoxin (digoxin) 0.25 mg tablets.  Her digoxin serum concentration at 8 hours post ingestion was 16.2 ng/ml.  While in the ED, the patient’s heart rate decreased to 30 beats/minute and she became hypotensive.  Her serum potassium was 5.6 mEq/L.

Which of the following statements regarding Digibind dosage is correct?

A. A digoxin serum concentration is required to determine the Digibind dose.
 
B. Patient weight is not required for the Digibind dose.
 
C. Each vial of Digibind will bind 1 mg of digoxin.
 
D. A digoxin serum concentration obtained 3 hours after ingestion will reflect a post-distribution serum concentration.
 
E. Multiple methods can be utilized to calculate a Digibind dose for this patient.
 

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