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Module XV - Drugs / Chemicals in Human Breast Milk
INTRODUCTION
Welcome to Module 15 of the American Association
of Poison Control Center’s electronic continuing education program for
Specialists in Poison Information. This module will provide a basic
overview of the distribution of drugs / chemicals into human milk.
Additionally, some frequently asked questions concerning drugs / chemicals
/ infectious diseases during breastfeeding will be discussed.
release date - 4/3/99
most recent review date - 4/3/99
LEARNING OBJECTIVES
Upon completion of this electronic continuing education module the participant will be able to:
1. Understand the principles (pharmacokinetic theory) of drug /chemical distribution into human milk.
2. Understand the value of breastfeeding for the infant and the mother compared to the potential toxicity associated with the use of selected drugs / chemicals during breastfeeding.
3. Recognize the importance of monitoring nursing
infants and mothers while the mother is exposed to drugs /chemicals.
AUTHOR
Peter Ciancaglini, PharmD
REVIEW PANEL
Daniel Cobaugh, PharmD
Lorne K. Garrettson, MD
Prashant Joshi, MD
Ruth Lawrence, MD
Christine Stork, PharmD
Paul Wax, MD
REFERENCES
Drugs in Breast Milk. In: Lawrence RA, Lawrence RM, editors. Breastfeeding, A Guide for the Medical Professional. St. Louis: Mosby, Inc., 1999: 351-393.
Appendix D, Drugs in Breast Milk and the Effect on the Infant. In: Lawrence RA, Lawrence RM, editors. Breastfeeding, A Guide for the Medical Professional. St. Louis: Mosby, Inc., 1999: 744-867.
Lawrence, RM. Transmission of Infectious
Diseases Through Breast Milk and Breastfeeding. In: Lawrence RA,
Lawrence RM, editors. Breastfeeding, A Guide for the Medical Professional.
St. Louis: Mosby, Inc., 1999: 563-616.
AUTHOR DECLARATION INFORMATION
As an accredited CME sponsor, the University of
Rochester Office of Continuing Professional Education requires that its
authors comply with ACCME Standards for Commercial Support of CME.
All authors are required to disclose any significant financial interest
or relationship that they may have with a supporting company or the manufacturer(s)
of any commercial product/service that will be discussed in the materials
they present.
ACCME STANDARDS OF COMMERCIAL SUPPORT OF CME
These standards require that materials be free
of commercial bias and that any information regarding commercial products/services
be based on scientific methods generally accepted by the medical community.
When discussing therapeutic options, it is our preference that only generic
names be used. If it is necessary to use a trade name, then those
of several companies must be used. Further, should the presentation
include discussion of any unlabelled or investigational use of a commercial
product, the author required to disclose this to the reader.
AUTHOR DECLARATIONS
NO DISCLOSURES have been made by the author(s)
of this module that could be perceived as a real or apparent conflict of
interest in the context of the subject of their presentation(s).
CERTIFICATION
The University of Rochester School of Medicine and Dentistry is accredited by the Accreditation Council for Continuing Medical Education to sponsor continuing medical education for physicians.
The University of Rochester School of Medicine and Dentistry designates this educational activity for a maximum of 3.0 hours in Category 1 credit towards the AMA Physician's Recognition Award. Each physician should claim only those hours of credit that he/she actually spent in the educational activity.
This CME activity was planned and
produced in accordance with the Essentials and Standards of the Accreditation
Council for Continuing Medical Education.