Saturday May 1, 1999 - Question 8

Which of the following statements about protamine is correct?

A. Heparin is bound by protamine resulting in the formation of an inactive salt.

B. Anaphylactic and anaphylactoid reactions have not been reported after protamine administration.

C. Rebound effects from heparin have not been observed following protamine administration.

D. One mg of protamine has the ability to neutralize 10,000 units of heparin.

E. Protamine should be administered as a continuous infusion over 60 minutes
 
 

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