ELECTRONIC CONTINUING EDUCATION FOR
SPECIALISTS IN POISON INFORMATION

Module VIII -  A Review of Lithium Toxicity

INTRODUCTION

Welcome to the American Association of Poison Control Center’s electronic continuing education program for Specialists in Poison Information.  This fourteen-day module will provide a review of lithium toxicity.
 

LEARNING OBJECTIVES

In regard to lithium, upon completion of this electronic continuing education module the participant will be able to:

1. Describe factors that contribute to toxicity.

2. Describe pharmacokinetic characteristics and their relationship to clinical presentation and treatment..

3. Discuss clinical manifestations of acute and chronic toxicity.

4. Discuss the management of the poisoned patient.
 

AUTHORS

Peter Ciancaglini, PharmD
Daniel Cobaugh, Pharm.D.
 

REVIEW PANEL

William Chiang, M.D.
Prashant Joshi, M.D.
Ruth Lawrence. M.D.
Sandra Schneider, M.D.
Christine Stork, M.D.
Paul Wax, M.D.
 

REFERENCES

Groleau G.  Lithium toxicity.  Emerg Med Clinics of North America 1994;12(2):511-31.

Henry G.  Lithium.  In: Goldfrank LR, Flomenbaum NE, Lewin NA, Weisman RS, Howland MA, Hoffman RS eds.   Goldfrank’s: Toxicologic Emergencies.  Stamford: Appleton & Lange;1998:967-74.

Krishel S, Jackimczyk K.  Cyclic Antidepressants, Lithium, and Neuroleptic Agents.  Pharmacology and Toxicology.  Emerg Med Clinics of North America 1991;9(1):53-86.

Okusa MD, Crystal LJT.  Clinical Manifestations and Management of Acute Lithium Intoxication.  The Am J of Med 1994;97:383-89.

Roberge RJ, Martin TG, Schneider SM.  The Use of Sodium Polystyrene Sulfonate In a Lithium Overdose.  Ann of Emerg Med 1993;22(12): 1911-5.