Sunday November 22, 1998 - Question 2

Which of the following statements concerning the pathogenesis of serotonin syndrome is correct?

A. Any drug, or combination of drugs, that increases serotonin type 1A activity, can produce serotonin syndrome.
B. Drug interactions rarely precipitate serotonin syndrome.
C. Drugs that increase central nervous system dopamine concentrations are not expected to cause serotonin syndrome.
D. Many different mechanisms, including an increase in serotonin metabolism, may be responsible for an increase in serotonin type 1A activity.
E. Meperidine and dextromethorphan are safe when given to patients taking a serotonergic agent.
 
 

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