Stephen L. Welle, Ph.D.

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After receiving his B.S. in Psychology from the University of Illinois, Dr. Welle obtained a Ph.D. in Neurobiology from Northern Illinois University. Dr. Welle's research deals with regulation of muscle protein metabolism and gene expression, and how these are affected by aging and by endogenous growth factors. He also collaborates with faculty in the neuromuscular research group (neurology department) to study the effects of muscular dystrophies on gene expression. Finally, Dr. Welle plays a critical role in running many of the core facilities at the University of Rochester, serving as Director of the Functional Genomics Center and the CRC Core laboratory.

Current Appointments

• Professor - Department of Medicine (SMD)

Education
PhD Neurobiology	Northern Illinois Univ	1978
BS Liberal Arts & Sciences	Univ of Illinois	1974

Recent Journal Articles
Showing the 5 most recent journal articles. (111 available)
Welle S; Burgess K; Mehta S. "Stimulation of skeletal muscle myofibrillar protein synthesis and p70 S6 kinase phoshorylation by inhibition of myostatin in mature mice." American journal of physiology. Endocrinology and metabolism. 2009; Epub 2009 Jan 13.
Osborne RJ; Lin X; Welle S; Sobczak K; O'Rourke JR; Swanson MS; Thornton CA. "Transcriptional and post-transcriptional impact of toxic RNA in myotonic dystrophy." Human molecular genetics. 2009; Epub 2009 Feb 17.
Welle S. "Editorial Focus." American journal of physiology. Cell physiology. 2009; Epub 2009 Apr 08.
Welle S; Cardillo A; Zanche M; Tawil R. "Skeletal muscle gene expression after myostatin knockout in mature mice." Physiological genomics. 2009; Epub 2009 Jun 09.
Welle S; Burgess K; Thornton CA; Tawil R. "Relation between extent of myostatin depletion and muscle growth in mature mice." American journal of physiology. Endocrinology and metabolism. 2009; Epub 2009 Aug 04.