Patricia J. Simpson-Haidaris, Ph.D.
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Contact
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 610
Rochester, New York 14642
The role of fibrinogen in the pathogenesis of disease progression and resolution in the lung, the vasculature and in prostate and breast carcinoma.
Current Appointments
- Associate Professor - Department of Medicine (SMD)
- Associate Professor - Department of Microbiology and Immunology (SMD)
| Education | ||
|---|---|---|
| PhD Microbiology | University of Notre Dame | 1981 |
| MS Microbiology | University of Notre Dame | 1980 |
| BA Chemistry | Indiana University | 1973 |
| Post-Doctoral Training & Residency | |
|---|---|
| Post-doctoral Fellow. Dept of Microbiology and Immunology, University of North Carolina. Research Mentor: Kenneth Bott, Ph.D.: "Molecular cloning and expression in prokaryotes. | 1981 |
| Graduate Research Assistant, Dept of Microbiology, University of Notre Dame. Dissertation research performed under the direction of Dr. Charles Kulpa. Ph.D. Thesis: "Characterization and evaluation of large unilamellar liposomes as carriers of synthetic, single-stranded polyribonucleotides to affect RNA virus replication in culture. | 1979 - 1981 |
| Associate Development Scientist: Miles, Inc., Ames Division. Developed and implemented quality assurance control systems to define quality of new products from raw materials through in-process production, finished product and clinical trials following GMP, GLP and FDA regulations for new clinical diagnostic products in immunochemistry test systems. | 1976 - 1979 |
| Assistant Development Scientist: Miles Inc., Ames Division. Developed quality assurance control systems to define quality of new products for thyroid function, hepatitis B and urine chemistry test systems. Elkhart, IN 46515 | 1973 - 1976 |
| Recent Journal Articles |
|---|
| Showing the 5 most recent journal articles. (46 available) |
| Duan HO; Simpson-Haidaris PJ. "Cell type-specific differential induction of the human gamma-fibrinogen promoter by interleukin-6." The Journal of biological chemistry. 2006; 281(18):12451-7. Epub 2006 Mar 08. |
| Lawrence SO, Simpson-Haidaris PJ. "Regulated de novo biosynthesis of fibrinogen in lung alveolar epithelial cells". (Thromb Haemost 92) Chosen as Journal Club Highlights . Clin Lab 50 (2004): 715-30. |
| Wells J; Gigliotti F; Simpson-Haidaris PJ; Haidaris CG. "Epitope mapping of a protective monoclonal antibody against Pneumocystis carinii with shared reactivity to Streptococcus pneumoniae surface antigen PspA." Infection and immunity. 2004; 72(3):1548-56. |
| Lawrence SO; Simpson-Haidaris PJ. "Regulated de novo biosynthesis of fibrinogen in extrahepatic epithelial cells in response to inflammation." Thrombosis and haemostasis. 2004; 92(2):234-43. |
| Sahni A; Sahni SK; Simpson-Haidaris PJ; Francis CW. "Fibrinogen binding potentiates FGF-2 but not VEGF induced expression of u-PA, u-PAR, and PAI-1 in endothelial cells." Journal of thrombosis and haemostasis : JTH. 2004; 2(9):1629-36. |
