Robert D. Frisina, Ph.D.
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Current Appointments
- Professor - Department of Otolaryngology (SMD)
- Professor - Department of Biomedical Engineering (SMD)
- Professor - Department of Neurobiology and Anatomy (SMD)
| Journal Articles |
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| Showing 60 journal articles currently available. |
| Christensen N; D'Souza M; Zhu X; Frisina RD. "Age-related hearing loss: aquaporin 4 gene expression changes in the mouse cochlea and auditory midbrain." Brain research. 2009; 1253():27-34. Epub 2008 Dec 03. |
| Price K; Zhu X; Guimaraes PF; Vasilyeva ON; Frisina RD. "Hormone replacement therapy diminishes hearing in peri-menopausal mice." Hearing research. 2009; 252(1-2):29-36. Epub 2009 Mar 06. |
| Vasilyeva ON; Frisina ST; Zhu X; Walton JP; Frisina RD. "Interactions of hearing loss and diabetes mellitus in the middle age CBA/CaJ mouse model of presbycusis." Hearing research. 2009; 249(1-2):44-53. |
| Canlon B; Frisina RD. "Sex hormones and hearing: a pioneering area of enquiry." Hearing research. 2009; 252(1-2):1-2. |
| Frisina RD. "Age-related hearing loss: ear and brain mechanisms." Annals of the New York Academy of Sciences. 2009; 1170():708-17. |
| Frisina RD; Singh A; Bak M; Bozorg S; Seth R; Zhu X. "F1 (CBAxC57) mice show superior hearing in old age relative to their parental strains: Hybrid vigor or a new animal model for "Golden Ears"?" Neurobiology of aging. 2009; Epub 2009 Oct 28. |
| D'Souza M; Zhu X; Frisina RD. "Novel approach to select genes from RMA normalized microarray data using functional hearing tests in aging mice." Journal of neuroscience methods. 2008; 171(2):279-87. Epub 2008 Mar 27. |
| Tadros SF; D'Souza M; Zhu X; Frisina RD. "Apoptosis-related genes change their expression with age and hearing loss in the mouse cochlea." Apoptosis : an international journal on programmed cell death. 2008; 13(11):1303-21. |
| Tadros SF; D'Souza M; Zettel ML; Zhu X; Lynch-Erhardt M; Frisina RD. "Serotonin 2B receptor: upregulated with age and hearing loss in mouse auditory system." Neurobiology of aging. 2007; 28(7):1112-23. Epub 2006 Jul 05. |
| Tadros SF; D'Souza M; Zettel ML; Zhu X; Waxmonsky NC; Frisina RD. "Glutamate-related gene expression changes with age in the mouse auditory midbrain." Brain research. 2007; 1127(1):1-9. Epub 2006 Nov 17. |
| Frisina RD; Newman SR; Zhu X. "Auditory efferent activation in CBA mice exceeds that of C57s for varying levels of noise." The Journal of the Acoustical Society of America. 2007; 121(1):EL29-34. |
| Zettel ML; Zhu X; O'Neill WE; Frisina RD. "Age-related decline in Kv3.1b expression in the mouse auditory brainstem correlates with functional deficits in the medial olivocochlear efferent system." Journal of the Association for Research in Otolaryngology : JARO. 2007; 8(2):280-93. Epub 2007 Feb 15. |
| Zhu X; Vasilyeva ON; Kim S; Jacobson M; Romney J; Waterman MS; Tuttle D; Frisina RD. "Auditory efferent feedback system deficits precede age-related hearing loss: contralateral suppression of otoacoustic emissions in mice." The Journal of comparative neurology. 2007; 503(5):593-604. |
| Johnson DG; Zhu XX; Frisina RD; Borkholder DA. "Micro-molded cannulae for intracochlear infusions in small rodents." Conference proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2007; 2007():6617-20. |
| Frisina ST; Mapes F; Kim S; Frisina DR; Frisina RD. "Characterization of hearing loss in aged type II diabetics." Hearing research. 2006; 211(1-2):103-13. Epub 2005 Nov 23. |
| Frisina RD; Walton JP. "Age-related structural and functional changes in the cochlear nucleus." Hearing research. 2006; 216-217():216-23. Epub 2006 Apr 04. |
| Thompson SK; Zhu X; Frisina RD. "Estrogen blockade reduces auditory feedback in CBA mice." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2006; 135(1):100-5. |
| Guimaraes P; Frisina ST; Mapes F; Tadros SF; Frisina DR; Frisina RD. "Progestin negatively affects hearing in aged women." Proceedings of the National Academy of Sciences of the United States of America. 2006; 103(38):14246-9. Epub 2006 Sep 07. |
| Tadros SF; Frisina ST; Mapes F; Kim S; Frisina DR; Frisina RD. "Loss of peripheral right-ear advantage in age-related hearing loss." Audiology & neuro-otology. 2005; 10(1):44-52. |
| Tadros SF; Frisina ST; Mapes F; Frisina DR; Frisina RD. "Higher serum aldosterone correlates with lower hearing thresholds: a possible protective hormone against presbycusis." Hearing research. 2005; 209(1-2):10-8. Epub 2005 Jul 20. |
| Varghese GI; Zhu X; Frisina RD. "Age-related declines in distortion product otoacoustic emissions utilizing pure tone contralateral stimulation in CBA/CaJ mice." Hearing research. 2005; 209(1-2):60-7. Epub 2005 Aug 02. |
| Guimaraes P; Zhu X; Cannon T; Kim S; Frisina RD. "Sex differences in distortion product otoacoustic emissions as a function of age in CBA mice." Hearing research. 2004; 192(1-2):83-9. |
| Simon H; Frisina RD; Walton JP. "Age reduces response latency of mouse inferior colliculus neurons to AM sounds." The Journal of the Acoustical Society of America. 2004; 116(1):469-77. |
| Zettel ML; O'Neill WE; Trang TT; Frisina RD. "The effects of early bilateral deafening on calretinin expression in the dorsal cochlear nucleus of aged CBA/CaJ mice." Hearing research. 2003; 183(1-2):57-66. |
| Jacobson M; Kim S; Romney J; Zhu X; Frisina RD. "Contralateral suppression of distortion-product otoacoustic emissions declines with age: a comparison of findings in CBA mice with human listeners." The Laryngoscope. 2003; 113(10):1707-13. |
| Bowers WJ; Chen X; Guo H; Frisina DR; Federoff HJ; Frisina RD. "Neurotrophin-3 transduction attenuates cisplatin spiral ganglion neuron ototoxicity in the cochlea." Molecular therapy : the journal of the American Society of Gene Therapy. 2002; 6(1):12-8. |
| Walton JP; Simon H; Frisina RD. "Age-related alterations in the neural coding of envelope periodicities." Journal of neurophysiology. 2002; 88(2):565-78. |
| Kim S; Frisina DR; Frisina RD. "Effects of age on contralateral suppression of distortion product otoacoustic emissions in human listeners with normal hearing." Audiology & neuro-otology. 2002; 7(6):348-57. |
| Chen X; Frisina RD; Bowers WJ; Frisina DR; Federoff HJ. "HSV amplicon-mediated neurotrophin-3 expression protects murine spiral ganglion neurons from cisplatin-induced damage." Molecular therapy : the journal of the American Society of Gene Therapy. 2001; 3(6):958-63. |
| Frisina RD. "Subcortical neural coding mechanisms for auditory temporal processing." Hearing research. 2001; 158(1-2):1-27. |
| Zettel ML; O'Neill WE; Trang TT; Frisina RD. "Early bilateral deafening prevents calretinin up-regulation in the dorsal cortex of the inferior colliculus of aged CBA/CaJ mice." Hearing research. 2001; 158(1-2):131-8. |
| Fong CT; Wang M; Young EC; Hogan CA; Tallents RH; Kyrkanides S; Liptak GS; Sanger JA; Frisina RD. "Microtia associated with the Kabuki (Niikawa-Kuroki) syndrome." Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery. 2001; 125(5):557-8. |
| Frisina RD; Walton JP; Lynch-Armour MA; Byrd JD. "Inputs to a physiologically characterized region of the inferior colliculus of the young adult CBA mouse." Hearing research. 1998; 115(1-2):61-81. |
| Walton JP; Frisina RD; O'Neill WE. "Age-related alteration in processing of temporal sound features in the auditory midbrain of the CBA mouse." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1998; 18(7):2764-76. |
| Frisina DR; Frisina RD. "Speech recognition in noise and presbycusis: relations to possible neural mechanisms." Hearing research. 1997; 106(1-2):95-104. |
| Frisina RD; Walton JP; Lynch-Armour MA; Klotz DA. "Efferent projections of a physiologically characterized region of the inferior colliculus of the young adult CBA mouse." The Journal of the Acoustical Society of America. 1997; 101(5 Pt 1):2741-53. |
| Spongr VP; Flood DG; Frisina RD; Salvi RJ. "Quantitative measures of hair cell loss in CBA and C57BL/6 mice throughout their life spans." The Journal of the Acoustical Society of America. 1997; 101(6):3546-53. |
| Walton JP; Frisina RD; Ison JR; O'Neill WE. "Neural correlates of behavioral gap detection in the inferior colliculus of the young CBA mouse." Journal of comparative physiology. A, Sensory, neural, and behavioral physiology. 1997; 181(2):161-76. |
| Zettel ML; Frisina RD; Haider SE; O'Neill WE. "Age-related changes in calbindin D-28k and calretinin immunoreactivity in the inferior colliculus of CBA/CaJ and C57Bl/6 mice." The Journal of comparative neurology. 1997; 386(1):92-110. |
| O'Neill WE; Zettel ML; Whittemore KR; Frisina RD. "Calbindin D-28k immunoreactivity in the medial nucleus of the trapezoid body declines with age in C57BL/6, but not CBA/CaJ, mice." Hearing research. 1997; 112(1-2):158-66. |
| Frisina RD; Karcich KJ; Tracy TC; Sullivan DM; Walton JP; Colombo J. "Preservation of amplitude modulation coding in the presence of background noise by chinchilla auditory-nerve fibers." The Journal of the Acoustical Society of America. 1996; 99(1):475-90. |
| Frisina RD; Zettel ML; Kelley PE; Walton JP. "Distribution of calbindin D-28k immunoreactivity in the cochlear nucleus of the young adult chinchilla." Hearing research. 1995; 85(1-2):53-68. |
| Walton JP; Frisina RD; Meierhans LR. "Sensorineural hearing loss alters recovery from short-term adaptation in the C57BL/6 mouse." Hearing research. 1995; 88(1-2):19-26. |
| Swartz KP; Walton JP; Hantz EC; Goldhammer E; Crummer GC; Frisina RD. "P3 event-related potentials and performance of young and old subjects for music perception tasks." The International journal of neuroscience. 1994; 78(3-4):223-39. |
| Frisina RD; Walton JP; Karcich KJ. "Dorsal cochlear nucleus single neurons can enhance temporal processing capabilities in background noise." Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. 1994; 102(1):160-4. |
| Crummer GC; Walton JP; Wayman JW; Hantz EC; Frisina RD. "Neural processing of musical timbre by musicians, nonmusicians, and musicians possessing absolute pitch." The Journal of the Acoustical Society of America. 1994; 95(5 Pt 1):2720-7. |
| Quatela VC; Futran ND; Frisina RD. "Effects of cyanoacrylate tissue adhesives on cartilage graft viability." The Laryngoscope. 1993; 103(7):798-803. |
| Kelley PE; Frisina RD; Zettel ML; Walton JP. "Differential calbindin-like immunoreactivity in the brain stem auditory system of the chinchilla." The Journal of comparative neurology. 1992; 320(2):196-212. |
| Wayman JW; Frisina RD; Walton JP; Hantz EC; Crummer GC. "Effects of musical training and absolute pitch ability on event-related activity in response to sine tones." The Journal of the Acoustical Society of America. 1992; 91(6):3527-31. |
| Lesser HD; O'Neill WE; Frisina RD; Emerson RC. "ON-OFF units in the mustached bat inferior colliculus are selective for transients resembling "acoustic glint" from fluttering insect targets." Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. 1990; 82(1):137-48. |
| Frisina RD; Smith RL; Chamberlain SC. "Encoding of amplitude modulation in the gerbil cochlear nucleus: II. Possible neural mechanisms." Hearing research. 1990; 44(2-3):123-41. |
| Frisina RD; Smith RL; Chamberlain SC. "Encoding of amplitude modulation in the gerbil cochlear nucleus: I. A hierarchy of enhancement." Hearing research. 1990; 44(2-3):99-122. |
| Swartz KP; Hantz EC; Crummer GC; Walton JP; Frisina RD. "Does the melody linger on? Music cognition in Alzheimer's disease." Seminars in neurology. 1989; 9(2):152-8. |
| O'Neill WE; Frisina RD; Gooler DM. "Functional organization of mustached bat inferior colliculus: I. Representation of FM frequency bands important for target ranging revealed by 14C-2-deoxyglucose autoradiography and single unit mapping." The Journal of comparative neurology. 1989; 284(1):60-84. |
| Frisina RD; O'Neill WE; Zettel ML. "Functional organization of mustached bat inferior colliculus: II. Connections of the FM2 region." The Journal of comparative neurology. 1989; 284(1):85-107. |
| Frisina RD; Smith RL; Chamberlain SC. "Differential encoding of rapid changes in sound amplitude by second-order auditory neurons." Experimental brain research. Experimentelle Hirnforschung. Expérimentation cérébrale. 1985; 60(2):417-22. |
| Smith RL; Brachman ML; Frisina RD. "Sensitivity of auditory-nerve fibers to changes in intensity: a dichotomy between decrements and increments." The Journal of the Acoustical Society of America. 1985; 78(4):1310-6. |
| Frisina RD; Chamberlain SC; Brachman ML; Smith RL. "Anatomy and physiology of the gerbil cochlear nucleus: an improved surgical approach for microelectrode studies." Hearing research. 1982; 6(3):259-75. |
| Gescheider GA; Frisina RD; Verrillo RT. "Selective adaptation of vibrotactile thresholds." Sensory processes. 1979; 3(1):37-48. |
| Gescheider GA; Capraro AJ; Frisina RD; Hamer RD; Verrillo RT. "The effects of a surround on vibrotactile thresholds." Sensory processes. 1978; 2(2):99-115. |
