Ronnie Guillet, M.D., Ph.D.

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Dr. Guillet's primary research focus is in the area of neonatal brain development and injury. The developing brain is at risk from the effects of centrally-acting agents, including hypoxia, seizures, and medications. This risk is due in part to the fact that the brain may be more vulnerable during times of rapid maturational change. She has an active clinical research program, focused on the neonatal brain. She is directing several studies on neonatal seizures including long-term EEG monitoring, seizure burden, long-term follow-up, evaluation of current treatment, and potential new modes of treatment. In addition, she is the overall Primary Investigator for long term followup of children around the world who were enrolled in the CoolCap Study (headcooling with systemic hypothermia for infants with neonatal encephalopathy). Other areas of clinical research interest include Auditory Brainstem

Evoked Response: Its use as a tool to evaluate brain maturation and its relationship to hyperbili-rubinemia in preterm infants. She is also involved in a study to examine the potential genetic contributions to preterm birth. This work is supported by an NIH R34 and other grants from the NIH.

She serves as site investigator and principal investigator on national studies of hypothermia in the treatment of neonatal asphyxia and of phototherapy in extremely low birthweight neonates, including a substudy on the potential effect of hyperbilirubinemia and phototherapy on the maturation of the brainstem evoked response.

Specialty

Neonatology

Current Appointments

• Professor - Department of Pediatrics (SMD)