Mary T. Caserta, M.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 690
Rochester, New York 14642

Office: 585 275-6672

Lab: 585 273-5444

Fax: 585 273-1104

Portrait

Dr. Caserta's research interest are:

1) Epidemiology and Clinical Consequences of Infection with Human Herpesvirus-6, Herpesvirus-7 in Children with Special Emphasis on Epidemiology and Pathogenesis

2) Effects of Psychosocial factors on Susceptibility to Infectious Diseases.

The epidemiology and viral pathogenesis of human herpesvirus 6 (HHV6) is the focus of several ongoing basic research projects in the laboratory. One aspect of this work is the study of immune responses in children with latent and reactivated HHV6 infection. Previous experiments in the lab have shown that all children become infected with HHV6 during infancy or early childhood and that the virus remains latent in the peripheral blood mononuclear cells. Reactivation occurs in a small percentage of normal children and we are examining markers of immune function associated with reactivation, as well as possible outcomes on health in several populations. In addition, studies of the transmission of HHV6 are being pursued.

Specialty

Infectious Diseases

Current Appointments

Education
MD Medicine SUNY at Buffalo, School of Medicine 1984
BS Biology Marquette University 1980
Post-Doctoral Training & Residency
Pediatric Infectious Diseases/ Immunology Fellowship, University of Rochester School of Medicine and Dentistry, Rochester, NY 1988 - 1991
Assistant Chief Resident in Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 1986 - 1987
Residency in Pediatrics, Children's Hospital of Philadelphia, Philadelphia, PA 1984 - 1986
Fellowship Awards
James P. Wilmot Fellowship 1989 - 1992
William Bradford Fellowship, University of Rochester School of Medicine and Dentistry, Rochester, NY 1989 - 1992
Board Certifications
American Board of Pediatrics Present
American Board of Pediatrics, Pediatric Infectious Diseases Present
Recent Journal Articles
Showing the 5 most recent journal articles. (21 available)
Caserta MT; O'Connor TG; Wyman PA; Wang H; Moynihan J; Cross W; Tu X; Jin X. "The associations between psychosocial stress and the frequency of illness, and innate and adaptive immune function in children." Brain, behavior, and immunity. 2008; 22(6):933-40. Epub 2008 Mar 04.
Thingvoll ES; Guillet R; Caserta M; Dicenzo R. "Observational trial of a 48-hour gentamicin dosing regimen derived from Monte Carlo simulations in infants born at less than 28 weeks' gestation." The Journal of pediatrics. 2008; 153(4):530-4. Epub 2008 Jun 27.
Hall CB; Caserta MT; Schnabel K; Shelley LM; Marino AS; Carnahan JA; Yoo C; Lofthus GK; McDermott MP. "Chromosomal integration of human herpesvirus 6 is the major mode of congenital human herpesvirus 6 infection." Pediatrics. 2008; 122(3):513-20.
Wyman, P.A.; Moynihan, J.; Eberly, S.; Cox, C.; Cross, W.; Jin, X.; Caserta, M.T. "Association of family stress with natural killer cell activity and the frequency of illnesses in children." Arch Pediatr Adol Med 161 (2007): 228-234.
Cholette JM; Caserta M; Hardy D; Connolly HV. "Outcome of pulmonary function in Lemierre's disease-associated acute respiratory distress syndrome." Pediatric pulmonology. 2007; 42(4):389-92.