Regis James O'Keefe, M.D., Ph.D.
See information for Patients. Viewing information for Researchers.
Contact
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, New York 14642
Fax: 585 756-4727

Specialties
Bone Health, Osteoporosis, Oncology, Metabolic Bone Disease, and Geriatric Care
Current Appointments
- Chairman - Department of Orthopaedics (SMD)
- Director - Center for Musculoskeletal Research (SMD)
- Marjorie Strong Wehle Professor in Orthopaedics - Department of Orthopaedics (SMD)
- Professor - Department of Orthopaedics (SMD)
- Professor - Department of Pathology and Laboratory Medicine (SMD)
- Professor - Department of Environmental Medicine (SMD)
| Education | ||
|---|---|---|
| PhD Biochemistry | University of Rochester School of Medicine and Dentistry | 2000 |
| MD Medicine | Harvard Medical School | 1985 |
| BA Philosophy | Yale University | 1981 |
| Post-Doctoral Training & Residency | |
|---|---|
| Massachusetts General Hospital Fellowship in Orthopaedic Oncology | 1992 - 1993 |
| The University of Rochester Medical Center, Rochester, NY Resident in Orthopaedics | 1988 - 1992 |
| University of Rochester School of Medicine and Dentistry, Instructor and Fellow in Research Orthopaedic Research Laboratories | 1986 - 1988 |
| University of Rochester School of Medicine and Dentistry, Instructor and Fellow in Research, Endocrinology Training Grant | 1986 - 1988 |
| New England Deaconess Hospital Harvard Medical School Surgical Internship | 1985 - 1986 |
| Board Certifications | |
|---|---|
| Board Certification- Orthopaedics | Present |
Lab Description
The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.
Lab Website
http://www.urmc.rochester.edu/ortho/research/index.cfm
| Recent Journal Articles |
|---|
| Showing the 5 most recent journal articles. (203 available) |
| Zhu M; Tang D; Wu Q; Hao S; Chen M; Xie C; Rosier RN; O'Keefe RJ; Zuscik M; Chen D. "Activation of beta-catenin signaling in articular chondrocytes leads to osteoarthritis-like phenotype in adult beta-catenin conditional activation mice." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2009; 24(1):12-21. |
| Taylor DK; Meganck JA; Terkhorn S; Rajani R; Naik A; O'Keefe RJ; Goldstein SA; Hankenson KD. "Thrombospondin-2 Influences the Proportion of Cartilage and Bone During Fracture Healing." Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research. 2009; Epub 2009 Jan 05. |
| Crane DP; Gromov K; Li D; Søballe K; Wahnes C; Büchner H; Hilton MJ; O'Keefe RJ; Murray CK; Schwarz EM. "Efficacy of colistin-impregnated beads to prevent multidrug-resistant A. baumannii implant-associated osteomyelitis." Journal of orthopaedic research : official publication of the Orthopaedic Research Society. 2009; Epub 2009 Jan 27. |
| Hasslund,S.; Jacobson,J. A.; Dadali,T.; Basile,P.; Ulrich-Vinther,M.; Soballe,K.; Schwarz,E. M.; O'Keefe,R. J.; Mitten,D. J.; Awad,H. A.;. "Adhesions in a murine flexor tendon graft model: Autograft versus allograft reconstruction". J.Orthop.Res. (2008). |
| Tsutsumi,R.; Hock,C.; Bechtold,C. D.; Proulx,S. T.; Bukata,S. V.; Ito,H.; A Awad,H.; Nakamura,T.; O'Keefe,R. J.; Schwarz,E. M.;. "Differential effects of biologic versus bisphosphonate inhibition of wear debris-induced osteolysis assessed by longitudinal micro-CT". J.Orthop.Res. (2008). |

