Paul Thomas Rubery, Jr., M.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 665
Rochester, New York 14642

Fax: 585 756-4726

Portrait

The use of gene transfer to improve cartilage repair, ligament healing, and restoration of various additional tissues, including tendon and meniscus shows great promise. Other applications include intervertebral disc degeneration, aseptic loosening, osteoporosis, genetic diseases, and orthopaedic tumors. Dr. Rubery's research focuses on finding gene delivery systems that can mediate site-specific transduction restricted to within the margins of the defect during routine arthroscopy. He serves as a consulting scientist for LAGeT Musculoskeletal, LLC in the development of a technology process, termed LAGT (Light Activated Gene Therapy) for articular and meniscal cartilage repair, ligament and tendon healing and enhanced spinal fusion.

Specialty

Spine

Current Appointments

Education
MD Medicine Cornell University Medical College 1988
BA Biology Johns Hopkins University 1984
Post-Doctoral Training & Residency
Additional Professional Education Health Care Leadership Program (certificate program) University of Rochester Simon School of Business Completed 1999
Chief Residency The Hospital for Special Surgery, New York, NY Orthopaedic Surgery 1992 - 1993
Residency The Hospital for Special Surgery, New York, NY Orthopaedic Surgery 1989 - 1993
Internship The New York Hospital, New York, NY General Surgery 1988 - 1989
Fellowship Awards
Visiting Fellowship, Spinal Disorders Service, University of California San Francisco 1994
Louis A. Goldstein Spinal Surgery Fellowship, University of Rochester 1993 - 1994
Board Certifications
American Board of Orthopaedic Surgery 1996
National Board of Medical Examiners 1989

Lab Description

The Center for Musculoskeletal Research houses nearly 70 MD and PhD researchers and graduate and post-doctoral students. This team has been the top orthopaedics lab in the United States since 2006.

Lab Website

http://www.urmc.rochester.edu/ortho/research/index.cfm

Recent Journal Articles
Showing the 5 most recent journal articles. (15 available)
Perlmutter,D. H.; Campbell,S.; Rubery,P. T.; Vates,E. G.; Silberstein,H. J.;. "Aneurysmal bone cyst: surgical management in the pediatric cervical spine". Spine 34 (2009): E50-3.
Andersson,G. B.; Bridwell,K. H.; Danielsson,A.; Dolan,L. A.; Everett,C. R.; Fisher,C. G.; Mercado,E.; Mulpuri,K.; Richards,B. S.; Rubery,P. T.; Sponseller,P. D.; Weinstein,J. N.;. "Evidence-based medicine summary statement". Spine 32 (2007): S64-5.
Reynolds,D. G.; Hock,C.; Shaikh,S.; Jacobson,J.; Zhang,X.; Rubery,P. T.; Beck,C. A.; O'keefe,R. J.; Lerner,A. L.; Schwarz,E. M.; Awad,H. A.;. "Micro-computed tomography prediction of biomechanical strength in murine structural bone grafts". J.Biomech. 40 (2007): 3178-3186.
Xie,C.; Reynolds,D.; Awad,H.; Rubery,P. T.; Pelled,G.; Gazit,D.; Guldberg,R. E.; Schwarz,E. M.; O'Keefe,R. J.; Zhang,X.;. "Structural bone allograft combined with genetically engineered mesenchymal stem cells as a novel platform for bone tissue engineering". Tissue Eng. 13 (2007): 435-445.
Maloney,M. D.; Goater,J. J.; Parsons,R.; Ito,H.; O'Keefe,R. J.; Rubery,P. T.; Drissi,M. H.; Schwarz,E. M.;. "Safety and efficacy of ultraviolet-a light-activated gene transduction for gene therapy of articular cartilage defects". J.Bone Joint Surg.Am. 88 (2006): 753-761.