Robert S. Freeman, Ph.D.

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Contact

University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, New York 14642

Current Appointments

Education
PhD Biochemistry Univ of Cal San Diego 1991
MS Biochemistry Univ of Cal San Diego 1987
BS Chemistry University of Delaware 1985
Post-Doctoral Training & Residency
Department of Molecular Biology and Pharmacology, Washington University School of Medicine. Mentor: Dr. Eugene M. Johnson, Jr. 1991 - 1994
Fellowship Awards
NIH (NINDS) Individual Postdoctoral National Research Service Award Fellow, Washington University School of Medicine 1992 - 1994
NIH (NCI) Predoctoral National Research Service Award Trainee, University of California, San Diego 1987 - 1991
Recent Journal Articles
Showing the 5 most recent journal articles. (38 available)
Lomb DJ; Desouza LA; Franklin JL; Freeman RS. "Prolyl hydroxylase inhibitors depend on extracellular glucose and HIF-2{alpha} to inhibit cell death caused by NGF deprivation: evidence that HIF-2{alpha} has a role in NGF-promoted survival of sympathetic neurons." Molecular pharmacology. 2009; Epub 2009 Feb 09.
Guo Y; Schoell MC; Freeman RS. "The von Hippel-Lindau protein sensitizes renal carcinoma cells to apoptotic stimuli through stabilization of BIM(EL)." Oncogene. 2009; Epub 2009 Mar 23.
Xie L; Xiao K; Whalen EJ; Forrester MT; Freeman RS; Fong G; Gygi SP; Lefkowitz RJ; Stamler JS. "Oxygen-regulated beta(2)-adrenergic receptor hydroxylation by EGLN3 and ubiquitylation by pVHL." Science signaling. 2009; 2(78):ra33. Epub 2009 Jul 07.
Barone MC; Desouza LA; Freeman RS. "Pin1 promotes cell death in NGF-dependent neurons through a mechanism requiring c-Jun activity." Journal of neurochemistry. 2008; 106(2):734-45. Epub 2008 Apr 14.
Ratan RR; Siddiq A; Aminova L; Langley B; McConoughey S; Karpisheva K; Lee HH; Carmichael T; Kornblum H; Coppola G; Geschwind DH; Hoke A; Smirnova N; Rink C; Roy S; Sen C; Beattie MS; Hart RP; Grumet M; Sun D; Freeman RS; Semenza GL; Gazaryan I. "Small molecule activation of adaptive gene expression: tilorone or its analogs are novel potent activators of hypoxia inducible factor-1 that provide prophylaxis against stroke and spinal cord injury." Annals of the New York Academy of Sciences. 2008; 1147():383-94.