Sanjeev Kumar Sahni, Ph.D.
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Current Appointments
- Associate Professor - Department of Microbiology and Immunology (SMD)
| Journal Articles |
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| Showing 44 journal articles currently available. |
| Sahni, S.K., Kiriakidi, S., Colonne, M.P., Sahni, A., and Silverman, D.J. "Selective activation of Signal Transducer and Activator of Transcription (STAT) proteins STAT1 and STAT3 in human endothelial cells infected with Rickettsia rickettsii." Clinical Microbiology and Infection (2008). |
| Rydkina, E., Turpin, L.C., Silverman, D.J., and Sahni, S.K. "Rickettsia rickettsii infection of human pulmonary microvascular endothelial cells: modulation of cyclooxygenase-2 expression." Clinical Microbiology and Infection (2008). |
| Rydkina, E., Turpin, L.C., and Sahni, S.K. "Activation of p38 MAP kinase module facilitates in vitro host cell invasion by Rickettsia rickettsii." Journal of Medical Microbiology (2008): 57: 1172-1175. |
| Sahni, S.K., Rydkina, E., and Sahni, A. "The proteasome inhibitor MG132 induces nuclear translocation of erythroid transcription factor Nrf2 and cyclooxygenase-2 expression in human vascular endothelial cells." Thrombosis Research Epub ahead of print (2008). |
| Sahni A; Simpson-Haidaris PJ; Sahni SK; Vaday GG; Francis CW. "Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2 (FGF-2)." Journal of thrombosis and haemostasis : JTH. 2008; 6(1):176-83. Epub 2007 Oct 22. |
| Sahni SK. "Endothelial cell infection and hemostasis." Thrombosis research. 2007; 119(5):531-49. Epub 2006 Jul 26. |
| Rydkina E; Sahni A; Silverman DJ; Sahni SK. "Comparative analysis of host-cell signalling mechanisms activated in response to infection with Rickettsia conorii and Rickettsia typhi." Journal of medical microbiology. 2007; 56(Pt 7):896-906. |
| Rydkina E; Sahni A; Baggs RB; Silverman DJ; Sahni SK. "Infection of human endothelial cells with spotted Fever group rickettsiae stimulates cyclooxygenase 2 expression and release of vasoactive prostaglandins." Infection and immunity. 2006; 74(9):5067-74. |
| Clifton DR; Rydkina E; Freeman RS; Sahni SK. "NF-kappaB activation during Rickettsia rickettsii infection of endothelial cells involves the activation of catalytic IkappaB kinases IKKalpha and IKKbeta and phosphorylation-proteolysis of the inhibitor protein IkappaBalpha." Infection and immunity. 2005; 73(1):155-65. |
| Sahni A; Sahni SK; Francis CW. "Endothelial cell activation by IL-1beta in the presence of fibrinogen requires alphavbeta3." Arteriosclerosis, thrombosis, and vascular biology. 2005; 25(10):2222-7. Epub 2005 Aug 25. |
| Rydkina E; Silverman DJ; Sahni SK. "Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response." Cellular microbiology. 2005; 7(10):1519-30. |
| Rydkina E; Silverman DJ; Sahni SK. "Similarities and differences in host cell signaling following infection with different Rickettsia species." Annals of the New York Academy of Sciences. 2005; 1063():203-6. |
| Sahni SK; Rydkina E; Sahni A; Joshi SG; Silverman DJ. "Potential roles for regulatory oxygenases in rickettsial pathogenesis." Annals of the New York Academy of Sciences. 2005; 1063():207-14. |
| Sahni A; Guo M; Sahni SK; Francis CW. "Interleukin-1beta but not IL-1alpha binds to fibrinogen and fibrin and has enhanced activity in the bound form." Blood. 2004; 104(2):409-14. Epub 2004 Mar 23. |
| Rydkina E; Sahni SK; Santucci LA; Turpin LC; Baggs RB; Silverman DJ. "Selective modulation of antioxidant enzyme activities in host tissues during Rickettsia conorii infection." Microbial pathogenesis. 2004; 36(6):293-301. |
| Joshi SG; Francis CW; Silverman DJ; Sahni SK. "NF-kappaB activation suppresses host cell apoptosis during Rickettsia rickettsii infection via regulatory effects on intracellular localization or levels of apoptogenic and anti-apoptotic proteins." FEMS microbiology letters. 2004; 234(2):333-41. |
| Sahni A; Sahni SK; Simpson-Haidaris PJ; Francis CW. "Fibrinogen binding potentiates FGF-2 but not VEGF induced expression of u-PA, u-PAR, and PAI-1 in endothelial cells." Journal of thrombosis and haemostasis : JTH. 2004; 2(9):1629-36. |
| Guo M; Sahni SK; Sahni A; Francis CW. "Fibrinogen regulates the expression of inflammatory chemokines through NF-kappaB activation of endothelial cells." Thrombosis and haemostasis. 2004; 92(4):858-66. |
| Joshi SG; Sahni SK. "Immunofluorescent detection of activation of initiator caspases-8 and -9 during pharmacologically induced apoptosis of cultured HeLa and endothelial cells." Histochemistry and cell biology. 2003; 119(6):463-8. Epub 2003 May 23. |
| Joshi SG; Francis CW; Silverman DJ; Sahni SK. "Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity." Infection and immunity. 2003; 71(7):4127-36. |
| Sahni SK; Rydkina E; Joshi SG; Sporn LA; Silverman DJ. "Interactions of Rickettsia rickettsii with endothelial nuclear factor-kappaB in a "cell-free" system." Annals of the New York Academy of Sciences. 2003; 990():635-41. |
| Rydkina E; Sahni A; Silverman DJ; Sahni SK. "Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression." Infection and immunity. 2002; 70(8):4045-52. |
| Suchkova VN; Baggs RB; Sahni SK; Francis CW. "Ultrasound improves tissue perfusion in ischemic tissue through a nitric oxide dependent mechanism." Thrombosis and haemostasis. 2002; 88(5):865-70. |
| Li Z; Nalcacioglu IA; Ranka S; Sahni SK; Palta JR; Tomé W; Kim S. "An algorithm for automatic, computed-tomography-based source localization after prostate implant." Medical physics. 2001; 28(7):1410-5. |
| Sahni SK; Turpin LC; Brown TL; Sporn LA. "Involvement of protein kinase C in Rickettsia rickettsii-induced transcriptional activation of the host endothelial cell." Infection and immunity. 1999; 67(12):6418-23. |
| Clifton DR; Goss RA; Sahni SK; van Antwerp D; Baggs RB; Marder VJ; Silverman DJ; Sporn LA. "NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection." Proceedings of the National Academy of Sciences of the United States of America. 1998; 95(8):4646-51. |
| Sahni SK; Van Antwerp DJ; Eremeeva ME; Silverman DJ; Marder VJ; Sporn LA. "Proteasome-independent activation of nuclear factor kappaB in cytoplasmic extracts from human endothelial cells by Rickettsia rickettsii." Infection and immunity. 1998; 66(5):1827-33. |
| Sporn LA; Sahni SK; Lerner NB; Marder VJ; Silverman DJ; Turpin LC; Schwab AL. "Rickettsia rickettsii infection of cultured human endothelial cells induces NF-kappaB activation." Infection and immunity. 1997; 65(7):2786-91. |
| Boguslavsky LI; Geng L; Kovalev IP; Sahni SK; Xu Z; Skotheim TA; Laurinavicius V; Persson B; Gorton L. "Amperometric thin film biosensors based on glucose dehydrogenase and Toluidine Blue O as catalyst for NADH electrooxidation." Biosensors & bioelectronics. 1995; 10(8):693-704. |
| Javaid JI; Sahni SK; Pandey SC; Davis JM. "Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions." European journal of pharmacology. 1993; 238(2-3):425-9. |
| Sahni SK; Saxena N; Puri SK; Dutta GP; Pandey VC. "Studies on glycolytic enzymes of Plasmodium knowlesi, a simian malaria parasite, and infected host erythrocytes." Zentralblatt für Bakteriologie : international journal of medical microbiology. 1992; 277(2):245-9. |
| Sahni SK; Saxena N; Puri SK; Dutta GP; Pandey VC. "Alterations in host regulatory glycolytic enzymes during pathogenesis of primate malaria and following chloroquine therapy." International journal for parasitology. 1992; 22(2):247-9. |
| Srivastava P; Sahni SK; Tripathi LM; Puri SK; Dutta GP; Pandey VC. "Kinetic and substrate binding characterization of hepatic mixed function oxidase system in monkeys with primaquine and (N1-3-acetyl-4-5-dihydro-2-furanyl)-N4-(methoxy-8-quinolinyl) 1,4-peptane-diamine." Biochemical pharmacology. 1992; 43(4):904-7. |
| Sahni SK; Saxena N; Puri SK; Dutta GP; Pandey VC. "NADP-specific isocitrate dehydrogenase from the simian malaria parasite Plasmodium knowlesi: partial purification and characterization." The Journal of protozoology. 1992; 39(2):338-42. |
| Srivastava, P., Sahni, S.K., Puri, S.K., Dutta, G.P., and Pande¬y, V.C. "Status of hepatic microsomal mixed function oxidase system during Plasmodium knowlesi infec¬tion and after chloro¬quine treatment of rhesus monkeys." Clinical Chemistry and Enzymology Communications 4 (1991): 203-208. |
| Sahni SK; Saxena N; Tekwani BL; Dutta GP; Pandey VC. "Status of hepatic heme and heme oxygenase during Plasmodium yoelii nigeriensis infection in mice." Experimental and molecular pathology. 1991; 55(1):55-62. |
| Saxena, N., Sahni, S.K., Chandra, S., Kant, S., Islam, A., Saxena, R., Dutta, G.P., and Pandey, V.C. "Studies on dehydrogenases of mastomys erythrocytes infected with chloroquine sensitive and resistant strains of Plasmodium berghei." Clinical Chemistry and Enzymology Communications 3 (1990): 219-223. |
| Pandey VC; Puri SK; Sahni SK; Srivastava P; Dutta GP. "Effect of anti-relapse antimalarial compound CDRI 80/53 and primaquine on hepatic mixed function oxidase system of rhesus monkey." Pharmacological research : the official journal of the Italian Pharmacological Society. 1990; 22(6):701-7. |
| Saxena, N., Puri, S.K., Sahni, S.K., Dutta, G.P., and Pandey, V.C. "Studies on methemoglobin and methemo¬globin reductase in monkey erythrocytes during Plasmodium knowlesi infection." Clinical Chemistry and Enzymology Communications 2 (1989): 55-59. |
| Sahni, S.K., Saxena, N., Puri, S.K., Dutta, G.P., and Pandey, V.C. "Regulatory enzymes of glycolytic cycle of simian malarial parasite, Plasmodium knowlesi." Indian Journal of Parasitology 12 (1988): 275-278. |
| Campbell WW; Sahni SK; Pridgeon RM; Riaz G; Leshner RT. "Intraoperative electroneurography: management of ulnar neuropathy at the elbow." Muscle & nerve. 1988; 11(1):75-81. |
| Campbell WW; Pridgeon RM; Sahni SK. "Entrapment neuropathy of the ulnar nerve at its point of exit from the flexor carpi ulnaris muscle." Muscle & nerve. 1988; 11(5):467-70. |
| Rydkina, E., Sahni, A., Baggs, R.B., Silverman, D.J, and Sahni, S.K. "Infection of human endothelial cells with spotted fever group rickettsiae stimulates cyclooxygenase-2 expression and release of prostaglandins". Infection and Immunity. |
| Sahni, S.K. "Endothelial cell infection and hemostasis". Thrombosis Research: Invited review. |

