Sanjeev Kumar Sahni, Ph.D.

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Journal Articles
Showing 44 journal articles currently available.
Sahni, S.K., Kiriakidi, S., Colonne, M.P., Sahni, A., and Silverman, D.J. "Selective activation of Signal Transducer and Activator of Transcription (STAT) proteins STAT1 and STAT3 in human endothelial cells infected with Rickettsia rickettsii." Clinical Microbiology and Infection (2008).
Rydkina, E., Turpin, L.C., Silverman, D.J., and Sahni, S.K. "Rickettsia rickettsii infection of human pulmonary microvascular endothelial cells: modulation of cyclooxygenase-2 expression." Clinical Microbiology and Infection (2008).
Rydkina, E., Turpin, L.C., and Sahni, S.K. "Activation of p38 MAP kinase module facilitates in vitro host cell invasion by Rickettsia rickettsii." Journal of Medical Microbiology (2008): 57: 1172-1175.
Sahni, S.K., Rydkina, E., and Sahni, A. "The proteasome inhibitor MG132 induces nuclear translocation of erythroid transcription factor Nrf2 and cyclooxygenase-2 expression in human vascular endothelial cells." Thrombosis Research Epub ahead of print (2008).
Sahni A; Simpson-Haidaris PJ; Sahni SK; Vaday GG; Francis CW. "Fibrinogen synthesized by cancer cells augments the proliferative effect of fibroblast growth factor-2 (FGF-2)." Journal of thrombosis and haemostasis : JTH. 2008; 6(1):176-83. Epub 2007 Oct 22.
Sahni SK. "Endothelial cell infection and hemostasis." Thrombosis research. 2007; 119(5):531-49. Epub 2006 Jul 26.
Rydkina E; Sahni A; Silverman DJ; Sahni SK. "Comparative analysis of host-cell signalling mechanisms activated in response to infection with Rickettsia conorii and Rickettsia typhi." Journal of medical microbiology. 2007; 56(Pt 7):896-906.
Rydkina E; Sahni A; Baggs RB; Silverman DJ; Sahni SK. "Infection of human endothelial cells with spotted Fever group rickettsiae stimulates cyclooxygenase 2 expression and release of vasoactive prostaglandins." Infection and immunity. 2006; 74(9):5067-74.
Clifton DR; Rydkina E; Freeman RS; Sahni SK. "NF-kappaB activation during Rickettsia rickettsii infection of endothelial cells involves the activation of catalytic IkappaB kinases IKKalpha and IKKbeta and phosphorylation-proteolysis of the inhibitor protein IkappaBalpha." Infection and immunity. 2005; 73(1):155-65.
Sahni A; Sahni SK; Francis CW. "Endothelial cell activation by IL-1beta in the presence of fibrinogen requires alphavbeta3." Arteriosclerosis, thrombosis, and vascular biology. 2005; 25(10):2222-7. Epub 2005 Aug 25.
Rydkina E; Silverman DJ; Sahni SK. "Activation of p38 stress-activated protein kinase during Rickettsia rickettsii infection of human endothelial cells: role in the induction of chemokine response." Cellular microbiology. 2005; 7(10):1519-30.
Rydkina E; Silverman DJ; Sahni SK. "Similarities and differences in host cell signaling following infection with different Rickettsia species." Annals of the New York Academy of Sciences. 2005; 1063():203-6.
Sahni SK; Rydkina E; Sahni A; Joshi SG; Silverman DJ. "Potential roles for regulatory oxygenases in rickettsial pathogenesis." Annals of the New York Academy of Sciences. 2005; 1063():207-14.
Sahni A; Guo M; Sahni SK; Francis CW. "Interleukin-1beta but not IL-1alpha binds to fibrinogen and fibrin and has enhanced activity in the bound form." Blood. 2004; 104(2):409-14. Epub 2004 Mar 23.
Rydkina E; Sahni SK; Santucci LA; Turpin LC; Baggs RB; Silverman DJ. "Selective modulation of antioxidant enzyme activities in host tissues during Rickettsia conorii infection." Microbial pathogenesis. 2004; 36(6):293-301.
Joshi SG; Francis CW; Silverman DJ; Sahni SK. "NF-kappaB activation suppresses host cell apoptosis during Rickettsia rickettsii infection via regulatory effects on intracellular localization or levels of apoptogenic and anti-apoptotic proteins." FEMS microbiology letters. 2004; 234(2):333-41.
Sahni A; Sahni SK; Simpson-Haidaris PJ; Francis CW. "Fibrinogen binding potentiates FGF-2 but not VEGF induced expression of u-PA, u-PAR, and PAI-1 in endothelial cells." Journal of thrombosis and haemostasis : JTH. 2004; 2(9):1629-36.
Guo M; Sahni SK; Sahni A; Francis CW. "Fibrinogen regulates the expression of inflammatory chemokines through NF-kappaB activation of endothelial cells." Thrombosis and haemostasis. 2004; 92(4):858-66.
Joshi SG; Sahni SK. "Immunofluorescent detection of activation of initiator caspases-8 and -9 during pharmacologically induced apoptosis of cultured HeLa and endothelial cells." Histochemistry and cell biology. 2003; 119(6):463-8. Epub 2003 May 23.
Joshi SG; Francis CW; Silverman DJ; Sahni SK. "Nuclear factor kappa B protects against host cell apoptosis during Rickettsia rickettsii infection by inhibiting activation of apical and effector caspases and maintaining mitochondrial integrity." Infection and immunity. 2003; 71(7):4127-36.
Sahni SK; Rydkina E; Joshi SG; Sporn LA; Silverman DJ. "Interactions of Rickettsia rickettsii with endothelial nuclear factor-kappaB in a "cell-free" system." Annals of the New York Academy of Sciences. 2003; 990():635-41.
Rydkina E; Sahni A; Silverman DJ; Sahni SK. "Rickettsia rickettsii infection of cultured human endothelial cells induces heme oxygenase 1 expression." Infection and immunity. 2002; 70(8):4045-52.
Suchkova VN; Baggs RB; Sahni SK; Francis CW. "Ultrasound improves tissue perfusion in ischemic tissue through a nitric oxide dependent mechanism." Thrombosis and haemostasis. 2002; 88(5):865-70.
Li Z; Nalcacioglu IA; Ranka S; Sahni SK; Palta JR; Tomé W; Kim S. "An algorithm for automatic, computed-tomography-based source localization after prostate implant." Medical physics. 2001; 28(7):1410-5.
Sahni SK; Turpin LC; Brown TL; Sporn LA. "Involvement of protein kinase C in Rickettsia rickettsii-induced transcriptional activation of the host endothelial cell." Infection and immunity. 1999; 67(12):6418-23.
Clifton DR; Goss RA; Sahni SK; van Antwerp D; Baggs RB; Marder VJ; Silverman DJ; Sporn LA. "NF-kappa B-dependent inhibition of apoptosis is essential for host cellsurvival during Rickettsia rickettsii infection." Proceedings of the National Academy of Sciences of the United States of America. 1998; 95(8):4646-51.
Sahni SK; Van Antwerp DJ; Eremeeva ME; Silverman DJ; Marder VJ; Sporn LA. "Proteasome-independent activation of nuclear factor kappaB in cytoplasmic extracts from human endothelial cells by Rickettsia rickettsii." Infection and immunity. 1998; 66(5):1827-33.
Sporn LA; Sahni SK; Lerner NB; Marder VJ; Silverman DJ; Turpin LC; Schwab AL. "Rickettsia rickettsii infection of cultured human endothelial cells induces NF-kappaB activation." Infection and immunity. 1997; 65(7):2786-91.
Boguslavsky LI; Geng L; Kovalev IP; Sahni SK; Xu Z; Skotheim TA; Laurinavicius V; Persson B; Gorton L. "Amperometric thin film biosensors based on glucose dehydrogenase and Toluidine Blue O as catalyst for NADH electrooxidation." Biosensors & bioelectronics. 1995; 10(8):693-704.
Javaid JI; Sahni SK; Pandey SC; Davis JM. "Repeated cocaine administration does not affect 5-HT receptor subtypes (5-HT1A, 5-HT2) in several rat brain regions." European journal of pharmacology. 1993; 238(2-3):425-9.
Sahni SK; Saxena N; Puri SK; Dutta GP; Pandey VC. "Studies on glycolytic enzymes of Plasmodium knowlesi, a simian malaria parasite, and infected host erythrocytes." Zentralblatt für Bakteriologie : international journal of medical microbiology. 1992; 277(2):245-9.
Sahni SK; Saxena N; Puri SK; Dutta GP; Pandey VC. "Alterations in host regulatory glycolytic enzymes during pathogenesis of primate malaria and following chloroquine therapy." International journal for parasitology. 1992; 22(2):247-9.
Srivastava P; Sahni SK; Tripathi LM; Puri SK; Dutta GP; Pandey VC. "Kinetic and substrate binding characterization of hepatic mixed function oxidase system in monkeys with primaquine and (N1-3-acetyl-4-5-dihydro-2-furanyl)-N4-(methoxy-8-quinolinyl) 1,4-peptane-diamine." Biochemical pharmacology. 1992; 43(4):904-7.
Sahni SK; Saxena N; Puri SK; Dutta GP; Pandey VC. "NADP-specific isocitrate dehydrogenase from the simian malaria parasite Plasmodium knowlesi: partial purification and characterization." The Journal of protozoology. 1992; 39(2):338-42.
Srivastava, P., Sahni, S.K., Puri, S.K., Dutta, G.P., and Pande¬y, V.C. "Status of hepatic microsomal mixed function oxidase system during Plasmodium knowlesi infec¬tion and after chloro¬quine treatment of rhesus monkeys." Clinical Chemistry and Enzymology Communications 4 (1991): 203-208.
Sahni SK; Saxena N; Tekwani BL; Dutta GP; Pandey VC. "Status of hepatic heme and heme oxygenase during Plasmodium yoelii nigeriensis infection in mice." Experimental and molecular pathology. 1991; 55(1):55-62.
Saxena, N., Sahni, S.K., Chandra, S., Kant, S., Islam, A., Saxena, R., Dutta, G.P., and Pandey, V.C. "Studies on dehydrogenases of mastomys erythrocytes infected with chloroquine sensitive and resistant strains of Plasmodium berghei." Clinical Chemistry and Enzymology Communications 3 (1990): 219-223.
Pandey VC; Puri SK; Sahni SK; Srivastava P; Dutta GP. "Effect of anti-relapse antimalarial compound CDRI 80/53 and primaquine on hepatic mixed function oxidase system of rhesus monkey." Pharmacological research : the official journal of the Italian Pharmacological Society. 1990; 22(6):701-7.
Saxena, N., Puri, S.K., Sahni, S.K., Dutta, G.P., and Pandey, V.C. "Studies on methemoglobin and methemo¬globin reductase in monkey erythrocytes during Plasmodium knowlesi infection." Clinical Chemistry and Enzymology Communications 2 (1989): 55-59.
Sahni, S.K., Saxena, N., Puri, S.K., Dutta, G.P., and Pandey, V.C. "Regulatory enzymes of glycolytic cycle of simian malarial parasite, Plasmodium knowlesi." Indian Journal of Parasitology 12 (1988): 275-278.
Campbell WW; Sahni SK; Pridgeon RM; Riaz G; Leshner RT. "Intraoperative electroneurography: management of ulnar neuropathy at the elbow." Muscle & nerve. 1988; 11(1):75-81.
Campbell WW; Pridgeon RM; Sahni SK. "Entrapment neuropathy of the ulnar nerve at its point of exit from the flexor carpi ulnaris muscle." Muscle & nerve. 1988; 11(5):467-70.
Rydkina, E., Sahni, A., Baggs, R.B., Silverman, D.J, and Sahni, S.K. "Infection of human endothelial cells with spotted fever group rickettsiae stimulates cyclooxygenase-2 expression and release of prostaglandins". Infection and Immunity.
Sahni, S.K. "Endothelial cell infection and hemostasis". Thrombosis Research: Invited review.