Sanjay Balkrishna Maggirwar, M.B.A., Ph.D.
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Current Appointments
- Associate Professor - Department of Microbiology and Immunology (SMD)
| Journal Articles |
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| Showing 50 journal articles currently available. |
| Schifitto G; Zhong J; Gill D; Peterson DR; Gaugh MD; Zhu T; Tivarus M; Cruttenden K; Maggirwar SB; Gendelman HE; Dewhurst S; Gelbard HA. "Lithium therapy for human immunodeficiency virus type 1-associated neurocognitive impairment." Journal of neurovirology. 2009; 15(2):176-86. |
| Sniderhan LF; Garcia-Bates TM; Burgart M; Bernstein SH; Phipps RP; Maggirwar SB. "Neurotrophin signaling through tropomyosin receptor kinases contributes to the survival and proliferation of Non-Hodgkin Lymphoma." Experimental hematology. 2009; Epub 2009 Aug 27. |
| Chugh P; Bradel-Tretheway B; Monteiro-Filho CM; Planelles V; Maggirwar SB; Dewhurst S; Kim B. "Akt inhibitors as an HIV-1 infected macrophage-specific anti-viral therapy." Retrovirology. 2008; 5():11. Epub 2008 Jan 31. |
| Yang SR; Valvo S; Yao H; Kode A; Rajendrasozhan S; Edirisinghe I; Caito S; Adenuga D; Henry R; Fromm G; Maggirwar S; Li JD; Bulger M; Rahman I. "IKK alpha causes chromatin modification on pro-inflammatory genes by cigarette smoke in mouse lung." American journal of respiratory cell and molecular biology. 2008; 38(6):689-98. Epub 2008 Jan 31. |
| Sniderhan LF; Stout A; Lu Y; Chao MV; Maggirwar SB. "Ankyrin-rich membrane spanning protein plays a critical role in nuclear factor-kappa B signaling." Molecular and cellular neurosciences. 2008; 38(3):404-16. Epub 2008 Apr 16. |
| Baglole CJ; Maggirwar SB; Gasiewicz TA; Thatcher TH; Phipps RP; Sime PJ. "The aryl hydrocarbon receptor attenuates tobacco smoke-induced cyclooxygenase-2 and prostaglandin production in lung fibroblasts through regulation of the NF-kappaB family member RelB." The Journal of biological chemistry. 2008; 283(43):28944-57. Epub 2008 Aug 12. |
| Norman JP; Perry SW; Reynolds HM; Kiebala M; De Mesy Bentley KL; Trejo M; Volsky DJ; Maggirwar SB; Dewhurst S; Masliah E; Gelbard HA. "HIV-1 Tat activates neuronal ryanodine receptors with rapid induction of the unfolded protein response and mitochondrial hyperpolarization." PloS one. 2008; 3(11):e3731. Epub 2008 Nov 14. |
| Garcia-Bates TM; Peslak SA; Baglole CJ; Maggirwar SB; Bernstein SH; Phipps RP. "Peroxisome proliferator-activated receptor gamma overexpression and knockdown: impact on human B cell lymphoma proliferation and survival." Cancer immunology, immunotherapy : CII. 2008; Epub 2008 Nov 19. |
| Chugh P; Fan S; Planelles V; Maggirwar SB; Dewhurst S; Kim B. "Infection of human immunodeficiency virus and intracellular viral Tat protein exert a pro-survival effect in a human microglial cell line." Journal of molecular biology. 2007; 366(1):67-81. Epub 2006 Nov 10. |
| Wang J; Gigliotti F; Bhagwat SP; Maggirwar SB; Wright TW. "Pneumocystis stimulates MCP-1 production by alveolar epithelial cells through a JNK-dependent mechanism." American journal of physiology. Lung cellular and molecular physiology. 2007; 292(6):L1495-505. Epub 2007 Feb 16. |
| Sui Z; Sniderhan LF; Schifitto G; Phipps RP; Gelbard HA; Dewhurst S; Maggirwar SB. "Functional synergy between CD40 ligand and HIV-1 Tat contributes to inflammation: implications in HIV type 1 dementia." Journal of immunology (Baltimore, Md. : 1950). 2007; 178(5):3226-36. |
| Thatcher TH; Maggirwar SB; Baglole CJ; Lakatos HF; Gasiewicz TA; Phipps RP; Sime PJ. "Aryl hydrocarbon receptor-deficient mice develop heightened inflammatory responses to cigarette smoke and endotoxin associated with rapid loss of the nuclear factor-kappaB component RelB." The American journal of pathology. 2007; 170(3):855-64. |
| Goyos A; Guselnikov S; Chida AS; Sniderhan LF; Maggirwar SB; Nedelkovska H; Robert J. "Involvement of nonclassical MHC class Ib molecules in heat shock protein-mediated anti-tumor responses." European journal of immunology. 2007; 37(6):1494-501. |
| Pingle SC; Jajoo S; Mukherjea D; Sniderhan LF; Jhaveri KA; Marcuzzi A; Rybak LP; Maggirwar SB; Ramkumar V. "Activation of the adenosine A1 receptor inhibits HIV-1 tat-induced apoptosis by reducing nuclear factor-kappaB activation and inducible nitric-oxide synthase." Molecular pharmacology. 2007; 72(4):856-67. Epub 2007 Jul 03. |
| Dewhurst S; Maggirwar SB; Schifitto G; Gendelman HE; Gelbard HA. "Glycogen synthase kinase 3 beta (GSK-3 beta) as a therapeutic target in neuroAIDS." Journal of neuroimmune pharmacology : the official journal of the Society on NeuroImmune Pharmacology. 2007; 2(1):93-6. Epub 2006 Dec 16. |
| Zeng L; Planelles V; Sui Z; Gartner S; Maggirwar SB; Dewhurst S; Ye L; Nerurkar VR; Yanagihara R; Lu Y. "HIV-1-based defective lentiviral vectors efficiently transduce human monocytes-derived macrophages and suppress replication of wild-type HIV-1." The journal of gene medicine. 2006; 8(1):18-28. |
| Yang SR; Chida AS; Bauter MR; Shafiq N; Seweryniak K; Maggirwar SB; Kilty I; Rahman I. "Cigarette smoke induces proinflammatory cytokine release by activation of NF-kappaB and posttranslational modifications of histone deacetylase in macrophages." American journal of physiology. Lung cellular and molecular physiology. 2006; 291(1):L46-57. Epub 2006 Feb 10. |
| Sui Z; Kovács AD; Maggirwar SB. "Recruitment of active glycogen synthase kinase-3 into neuronal lipid rafts." Biochemical and biophysical research communications. 2006; 345(4):1643-8. Epub 2006 May 24. |
| Sui Z; Fan S; Sniderhan L; Reisinger E; Litzburg A; Schifitto G; Gelbard HA; Dewhurst S; Maggirwar SB. "Inhibition of mixed lineage kinase 3 prevents HIV-1 Tat-mediated neurotoxicity and monocyte activation." Journal of immunology (Baltimore, Md. : 1950). 2006; 177(1):702-11. |
| Sui Z; Sniderhan LF; Fan S; Kazmierczak K; Reisinger E; Kovács AD; Potash MJ; Dewhurst S; Gelbard HA; Maggirwar SB. "Human immunodeficiency virus-encoded Tat activates glycogen synthase kinase-3beta to antagonize nuclear factor-kappaB survival pathway in neurons." The European journal of neuroscience. 2006; 23(10):2623-34. |
| Ray DM; Morse KM; Hilchey SP; Garcia TM; Felgar RE; Maggirwar SB; Phipps RP; Bernstein SH. "The novel triterpenoid 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO) induces apoptosis of human diffuse large B-cell lymphoma cells through a peroxisome proliferator-activated receptor gamma-independent pathway." Experimental hematology. 2006; 34(9):1202-11. |
| Cheng T; Petraglia AL; Li Z; Thiyagarajan M; Zhong Z; Wu Z; Liu D; Maggirwar SB; Deane R; Fernández JA; LaRue B; Griffin JH; Chopp M; Zlokovic BV. "Activated protein C inhibits tissue plasminogen activator-induced brain hemorrhage." Nature medicine. 2006; 12(11):1278-85. Epub 2006 Oct 29. |
| Jin N; Kovács AD; Sui Z; Dewhurst S; Maggirwar SB. "Opposite effects of lithium and valproic acid on trophic factor deprivation-induced glycogen synthase kinase-3 activation, c-Jun expression and neuronal cell death." Neuropharmacology. 2005; 48(4):576-83. Epub 2005 Jan 25. |
| Wang J; Gigliotti F; Maggirwar S; Johnston C; Finkelstein JN; Wright TW. "Pneumocystis carinii activates the NF-kappaB signaling pathway in alveolar epithelial cells." Infection and immunity. 2005; 73(5):2766-77. |
| Dou H; Ellison B; Bradley J; Kasiyanov A; Poluektova LY; Xiong H; Maggirwar S; Dewhurst S; Gelbard HA; Gendelman HE. "Neuroprotective mechanisms of lithium in murine human immunodeficiency virus-1 encephalitis." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2005; 25(37):8375-85. |
| Ramirez SH; Fan S; Maguire CA; Perry S; Hardiek K; Ramkumar V; Gelbard HA; Dewhurst S; Maggirwar SB. "Activation of adenosine A2A receptor protects sympathetic neurons against nerve growth factor withdrawal." Journal of neuroscience research. 2004; 77(2):258-69. |
| Kovács AD; Chakraborty-Sett S; Ramirez SH; Sniderhan LF; Williamson AL; Maggirwar SB. "Mechanism of NF-kappaB inactivation induced by survival signal withdrawal in cerebellar granule neurons." The European journal of neuroscience. 2004; 20(2):345-52. |
| Pingle SC; Sanchez JF; Hallam DM; Williamson AL; Maggirwar SB; Ramkumar V. "Hypertonicity inhibits lipopolysaccharide-induced nitric oxide synthase expression in smooth muscle cells by inhibiting nuclear factor kappaB." Molecular pharmacology. 2003; 63(6):1238-47. |
| Sanchez JF; Sniderhan LF; Williamson AL; Fan S; Chakraborty-Sett S; Maggirwar SB. "Glycogen synthase kinase 3beta-mediated apoptosis of primary cortical astrocytes involves inhibition of nuclear factor kappaB signaling." Molecular and cellular biology. 2003; 23(13):4649-62. |
| Dou H; Birusingh K; Faraci J; Gorantla S; Poluektova LY; Maggirwar SB; Dewhurst S; Gelbard HA; Gendelman HE. "Neuroprotective activities of sodium valproate in a murine model of human immunodeficiency virus-1 encephalitis." The Journal of neuroscience : the official journal of the Society for Neuroscience. 2003; 23(27):9162-70. |
| Tong N; Sanchez JF; Maggirwar SB; Ramirez SH; Guo H; Dewhurst S; Gelbard HA. "Activation of glycogen synthase kinase 3 beta (GSK-3beta) by platelet activating factor mediates migration and cell death in cerebellar granule neurons." The European journal of neuroscience. 2001; 13(10):1913-22. |
| Ramirez SH; Sanchez JF; Dimitri CA; Gelbard HA; Dewhurst S; Maggirwar SB. "Neurotrophins prevent HIV Tat-induced neuronal apoptosis via a nuclear factor-kappaB (NF-kappaB)-dependent mechanism." Journal of neurochemistry. 2001; 78(4):874-89. |
| Maggirwar SB; Ramirez S; Tong N; Gelbard HA; Dewhurst S. "Functional interplay between nuclear factor-kappaB and c-Jun integrated by coactivator p300 determines the survival of nerve growth factor-dependent PC12 cells." Journal of neurochemistry. 2000; 74(2):527-39. |
| Sun SC; Maggirwar SB; Harhaj EW; Uhlik M. "Binding of c-Rel to STAT5 target sequences in HTLV-I-transformed T cells." Oncogene. 1999; 18(7):1401-9. |
| Fine SM; Maggirwar SB; Elliott PR; Epstein LG; Gelbard HA; Dewhurst S. "Proteasome blockers inhibit TNF-alpha release by lipopolysaccharide stimulated macrophages and microglia: implications for HIV-1 dementia." Journal of neuroimmunology. 1999; 95(1-2):55-64. |
| Maggirwar SB; Tong N; Ramirez S; Gelbard HA; Dewhurst S. "HIV-1 Tat-mediated activation of glycogen synthase kinase-3beta contributes to Tat-mediated neurotoxicity." Journal of neurochemistry. 1999; 73(2):578-86. |
| New DR; Maggirwar SB; Epstein LG; Dewhurst S; Gelbard HA. "HIV-1 Tat induces neuronal death via tumor necrosis factor-alpha and activation of non-N-methyl-D-aspartate receptors by a NFkappaB-independent mechanism." The Journal of biological chemistry. 1998; 273(28):17852-8. |
| Maggirwar SB; Sarmiere PD; Dewhurst S; Freeman RS. "Nerve growth factor-dependent activation of NF-kappaB contributes to survival of sympathetic neurons." The Journal of neuroscience : the official journal of the Society for Neuroscience. 1998; 18(24):10356-65. |
| Good L; Maggirwar SB; Harhaj EW; Sun SC. "Constitutive dephosphorylation and activation of a member of the nuclear factor of activated T cells, NF-AT1, in Tax-expressing and type I human T-cell leukemia virus-infected human T cells." The Journal of biological chemistry. 1997; 272(3):1425-8. |
| Ford MS; Maggirwar SB; Rybak LP; Whitworth C; Ramkumar V. "Expression and function of adenosine receptors in the chinchilla cochlea." Hearing research. 1997; 105(1-2):130-40. |
| Maggirwar SB; Harhaj EW; Sun SC. "Regulation of the interleukin-2 CD28-responsive element by NF-ATp and various NF-kappaB/Rel transcription factors." Molecular and cellular biology. 1997; 17(5):2605-14. |
| Harhaj EW; Maggirwar SB; Sun SC. "Inhibition of p105 processing by NF-kappaB proteins in transiently transfected cells." Oncogene. 1996; 12(11):2385-92. |
| Good LF; Maggirwar SB; Kealiher A; Uhlik M; Sun SC. "Multiple structural domains within I kappa B alpha are required for its inducible degradation by both cytokines and phosphatase inhibitors." Biochemical and biophysical research communications. 1996; 223(1):123-8. |
| Good L; Maggirwar SB; Sun SC. "Activation of the IL-2 gene promoter by HTLV-I tax involves induction of NF-AT complexes bound to the CD28-responsive element." The EMBO journal. 1996; 15(14):3744-50. |
| Mandal M; Maggirwar SB; Sharma N; Kaufmann SH; Sun SC; Kumar R. "Bcl-2 prevents CD95 (Fas/APO-1)-induced degradation of lamin B and poly(ADP-ribose) polymerase and restores the NF-kappaB signaling pathway." The Journal of biological chemistry. 1996; 271(48):30354-9. |
| Harhaj EW; Maggirwar SB; Good L; Sun SC. "CD28 mediates a potent costimulatory signal for rapid degradation of IkappaBbeta which is associated with accelerated activation of various NF-kappaB/Rel heterodimers." Molecular and cellular biology. 1996; 16(12):6736-43. |
| Ramkumar V; Nie Z; Rybak LP; Maggirwar SB. "Adenosine, antioxidant enzymes and cytoprotection." Trends in pharmacological sciences. 1995; 16(9):283-5. |
| Sun SC; Maggirwar SB; Harhaj E. "Activation of NF-kappa B by phosphatase inhibitors involves the phosphorylation of I kappa B alpha at phosphatase 2A-sensitive sites." The Journal of biological chemistry. 1995; 270(31):18347-51. |
| Maggirwar SB; Harhaj E; Sun SC. "Activation of NF-kappa B/Rel by Tax involves degradation of I kappa B alpha and is blocked by a proteasome inhibitor." Oncogene. 1995; 11(5):993-8. |
| Maggirwar SB; Dhanraj DN; Somani SM; Ramkumar V. "Adenosine acts as an endogenous activator of the cellular antioxidant defense system." Biochemical and biophysical research communications. 1994; 201(2):508-15. |
