Robert Thomas Dirksen, Ph.D.
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Contact
University of Rochester
School of Medicine and Dentistry
601 Elmwood Ave, Box 711
Rochester, New York 14642
Office: 585 275-4824
Lab: 585 273-2169
Fax: 585 273-2652
Current Appointments
- Professor - Department of Pharmacology and Physiology (SMD)
| Education | ||
|---|---|---|
| PhD Pharmacology | University of Rochester | 1991 |
| MS Pharmacology | University of Rochester | 1988 |
| BS Biology | University of Notre Dame | 1985 |
| Post-Doctoral Training & Residency | |
|---|---|
| Postdoctoral Fellow, Colorado State University, Fort Collins, CO (Mentor: Kurt G. Beam, Ph. D.) | 1991 - 1996 |
| Fellowship Awards | |
|---|---|
| Individual National Research Service Award (#AR08243) - Colorado State University | 1993 - 1996 |
| National Institute of Drug Abuse Training Grant (#DA07232) - University of Rochester | 1988 - 1991 |
| Recent Journal Articles |
|---|
| Showing the 5 most recent journal articles. (69 available) |
| Kimura, K; Lueck, JD; Harvey, PJ; Pace, SM; Ikemoto, N; Casarotto, MG; *Dirksen, RT; and *Dulhunty, AF. "Alternative splicing of RyR1 influences the efficacy of skeletal EC coupling." Cell Calcium In Press (2009). |
| Boncompagni, S; Rossi, AE; Micaroni, M; Beznoussenko, GV; Polishchuk, RS; *Dirksen, RT; and *Protasi, F. "Muscle mitochondria are structurally linked to Ca2+ release units by developmentally regulated tethering structures." Mol. Biol. Cell (2009): 1058-1067. |
| Oestreich, EA; Malik, S; Goonasekera, SA; Blaxall, BC; Kelley, GG; Dirksen, RT; and Smrcka, AV. "Epac and PLC? regulate Ca2+ release in the heart by activation of PKC? and CaMKII." J. Biol. Chem. 284 (2009): 1514-1522. |
| Lyfenko, AD; Schuhmeier, RP; Avila, G; Melzer, W; and Dirksen, RT. "A recessive CCD mutation in RyR1 (V4849I) increases voltage-gated Ca2+ release and SR Ca2+ release flux following homozygous expression in dyspedic myotubes." In preparation (2009). |
| Andronache, Z.; Hamilton, SL; Dirksen, RT; and Melzer, W. "A retrograde signal from RyR1 alters DHP receptor inactivation and limits window Ca2+ leak in muscle fibers of Y522S RyR1 knock-in mice." Proc. Natl. Acad. Sci. In Press (2009). |
