Andrea Bottaro, Ph.D.

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Dr. Bottaro's research interests include B cell activation, the molecular biology of antibody gene expression and recombination, immunolglobulin class switching and transgenic/knock-out models.

Current Appointments

• Associate Professor - Department of Medicine (SMD)
• Associate Professor - Cancer Center (SMD)
• Associate Professor - Department of Microbiology and Immunology (SMD)

Education
PhD Biological Sci, All Other	Italy - Non-Medical School	1993
PhD Biological Science	Italy - Non-Medical School	1987

Post-Doctoral Training & Residency
Research Fellow Frederick W Alt Harvard Medical School and Children's Hospital Boston, Massachusetts	1991 - 1997
Postdoctoral Research Scientist Frederick W. Alt Columbia University in The City of New York New York, New York	1991

Lab Description

Dr. Bottaro's research interests include B cell activation, the molecular biology of antibody gene expression and reconbination, immunoglobulin class switching and trangenic/knock-out mouse models.

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Lab Website

http://www.urmc.rochester.edu/medicine/allergy/research/bottarolab.cfm

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Recent Journal Articles
Showing the 5 most recent journal articles. (26 available)
Kuzin II; Bagaeva L; Young FM; Bottaro A. "Requirement for enhancer specificity in immunoglobulin heavy chain locus regulation." Journal of immunology (Baltimore, Md. : 1950). 2008; 180(11):7443-50.
Wang PY; Young F; Chen CY; Stevens BM; Neering SJ; Rossi RM; Bushnell T; Kuzin I; Heinrich D; Bottaro A; Jordan CT. "The biologic properties of leukemias arising from BCR/ABL-mediated transformation vary as a function of developmental origin and activity of the p19ARF gene." Blood. 2008; 112(10):4184-92. Epub 2008 Aug 28.
Neering SJ; Bushnell T; Sozer S; Ashton J; Rossi RM; Wang PY; Bell DR; Heinrich D; Bottaro A; Jordan CT. "Leukemia stem cells in a genetically defined murine model of blast-crisis CML." Blood. 2007; 110(7):2578-85. Epub 2007 Jun 29.
Marr S; Morales H; Bottaro A; Cooper M; Flajnik M; Robert J. "Localization and differential expression of activation-induced cytidine deaminase in the amphibian Xenopus upon antigen stimulation and during early development." Journal of immunology (Baltimore, Md. : 1950). 2007; 179(10):6783-9.
Lee SC; Bottaro A; Chen L; Insel RA. "Mad1 is a transcriptional repressor of Bcl-6." Molecular immunology. 2006; 43(12):1965-71. Epub 2006 Jan 19.