Deborah Jayne Fowell, Ph.D.
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Current Appointments
- Associate Professor - Department of Microbiology and Immunology, Center for Vaccine Biology and Immunology (SMD)
| Journal Articles |
|---|
| Showing 39 journal articles currently available. |
| Sojka DK; Lazarski CA; Huang YH; Bromberg I; Hughson A; Fowell DJ. "Regulation of immunity at tissue sites of inflammation." Immunologic research. 2009; Epub 2009 Jan 31. |
| Fowell DJ. "Signals for the execution of Th2 effector function." Cytokine. 2009; Epub 2009 Feb 21. |
| Sojka DK; Hughson A; Fowell DJ. "CTLA-4 is required by CD4(+)CD25(+) Treg to control CD4(+) T-cell lymphopenia-induced proliferation." European journal of immunology. 2009; Epub 2009 May 21. |
| Katzman SD; Fowell DJ. "Pathogen-imposed skewing of mouse chemokine and cytokine expression at the infected tissue site." The Journal of clinical investigation. 2008; 118(2):801-11. |
| Sojka DK; Huang YH; Fowell DJ. "Mechanisms of regulatory T-cell suppression - a diverse arsenal for a moving target." Immunology. 2008; 124(1):13-22. Epub 2008 Mar 14. |
| Lazarski CA; Hughson A; Sojka DK; Fowell DJ. "Regulating Treg cells at sites of inflammation." Immunity. 2008; 29(4):511; author reply 512. |
| Au-Yeung BB; Fowell DJ. "A key role for Itk in both IFN gamma and IL-4 production by NKT cells." Journal of immunology (Baltimore, Md. : 1950). 2007; 179(1):111-9. |
| Zhao X; Zheng B; Huang Y; Yang D; Katzman S; Chang C; Fowell D; Zeng WP. "Interaction between GATA-3 and the transcriptional coregulator Pias1 is important for the regulation of Th2 immune responses." Journal of immunology (Baltimore, Md. : 1950). 2007; 179(12):8297-304. |
| Au-Yeung BB; Katzman SD; Fowell DJ. "Cutting edge: Itk-dependent signals required for CD4+ T cells to exert, but not gain, Th2 effector function." Journal of immunology (Baltimore, Md. : 1950). 2006; 176(7):3895-9. |
| Kobie JJ; Shah PR; Yang L; Rebhahn JA; Fowell DJ; Mosmann TR. "T regulatory and primed uncommitted CD4 T cells express CD73, which suppresses effector CD4 T cells by converting 5'-adenosine monophosphate to adenosine." Journal of immunology (Baltimore, Md. : 1950). 2006; 177(10):6780-6. |
| Sukiennicki TL; Fowell DJ. "Distinct molecular program imposed on CD4+ T cell targets by CD4+CD25+ regulatory T cells." Journal of immunology (Baltimore, Md. : 1950). 2006; 177(10):6952-61. |
| Sojka DK; Hughson A; Sukiennicki TL; Fowell DJ. "Early kinetic window of target T cell susceptibility to CD25+ regulatory T cell activity." Journal of immunology (Baltimore, Md. : 1950). 2005; 175(11):7274-80. |
| Morales-Tirado V; Johannson S; Hanson E; Howell A; Zhang J; Siminovitch KA; Fowell DJ. "Cutting edge: selective requirement for the Wiskott-Aldrich syndrome protein in cytokine, but not chemokine, secretion by CD4+ T cells." Journal of immunology (Baltimore, Md. : 1950). 2004; 173(2):726-30. |
| Gurunathan S; Stobie L; Prussin C; Sacks DL; Glaichenhaus N; Iwasaki A; Fowell DJ; Locksley RM; Chang JT; Wu CY; Seder RA. "Requirements for the maintenance of Th1 immunity in vivo following DNA vaccination: a potential immunoregulatory role for CD8+ T cells." Journal of immunology (Baltimore, Md. : 1950). 2000; 165(2):915-24. |
| Locksley RM; Pingel S; Lacy D; Wakil AE; Bix M; Fowell DJ. "Susceptibility to infectious diseases: Leishmania as a paradigm." The Journal of infectious diseases. 1999; 179 Suppl 2():S305-8. |
| Pingel S; Launois P; Fowell DJ; Turck CW; Southwood S; Sette A; Glaichenhaus N; Louis JA; Locksley RM. "Altered ligands reveal limited plasticity in the T cell response to a pathogenic epitope." The Journal of experimental medicine. 1999; 189(7):1111-20. |
| Fowell DJ; Locksley RM. "Leishmania major infection of inbred mice: unmasking genetic determinants of infectious diseases." BioEssays : news and reviews in molecular, cellular and developmental biology. 1999; 21(6):510-8. |
| Heath VL; Hutchings P; Fowell DJ; Cooke A; Mason DW. "Peptides derived from murine insulin are diabetogenic in both rats and mice, but the disease-inducing epitopes are different: evidence against a common environmental cross-reactivity in the pathogenicity of type 1 diabetes." Diabetes. 1999; 48(11):2157-65. |
| Fowell DJ; Shinkai K; Liao XC; Beebe AM; Coffman RL; Littman DR; Locksley RM. "Impaired NFATc translocation and failure of Th2 development in Itk-deficient CD4+ T cells." Immunity. 1999; 11(4):399-409. |
| Pippig SD; Peña-Rossi C; Long J; Godfrey WR; Fowell DJ; Reiner SL; Birkeland ML; Locksley RM; Barclay AN; Killeen N. "Robust B cell immunity but impaired T cell proliferation in the absence of CD134 (OX40)." Journal of immunology (Baltimore, Md. : 1950). 1999; 163(12):6520-9. |
| Reiner SL; Fowell DJ; Moskowitz NH; Swier K; Brown DR; Brown CR; Turck CW; Scott PA; Killeen N; Locksley RM. "Control of Leishmania major by a monoclonal alpha beta T cell repertoire." Journal of immunology (Baltimore, Md. : 1950). 1998; 160(2):884-9. |
| Wakil AE; Wang ZE; Ryan JC; Fowell DJ; Locksley RM. "Interferon gamma derived from CD4(+) T cells is sufficient to mediate T helper cell type 1 development." The Journal of experimental medicine. 1998; 188(9):1651-6. |
| Fowell DJ; Bix M; Shinkai K; Lacy D; Locksley RM. "Disease susceptibility and development of the cytokine repertoire in the murine Leishmania major model." European cytokine network. 1998; 9(3 Suppl):102-6. |
| Locksley RM; Fowell DJ; Shinkai K; Wakil AE; Lacy D; Bix M. "Development of CD4+ effector T cells and susceptibility to infectious diseases." Advances in experimental medicine and biology. 1998; 452():45-52. |
| Fowell DJ; Magram J; Turck CW; Killeen N; Locksley RM. "Impaired Th2 subset development in the absence of CD4." Immunity. 1997; 6(5):559-69. |
| Hagenbaugh A; Sharma S; Dubinett SM; Wei SH; Aranda R; Cheroutre H; Fowell DJ; Binder S; Tsao B; Locksley RM; Moore KW; Kronenberg M. "Altered immune responses in interleukin 10 transgenic mice." The Journal of experimental medicine. 1997; 185(12):2101-10. |
| Heath VL; Saoudi A; Seddon BP; Moore NC; Fowell DJ; Mason DW. "The role of the thymus in the control of autoimmunity." Journal of autoimmunity. 1996; 9(2):241-6. |
| Ramírez F; Fowell DJ; Puklavec M; Simmonds S; Mason D. "Glucocorticoids promote a TH2 cytokine response by CD4+ T cells in vitro." Journal of immunology (Baltimore, Md. : 1950). 1996; 156(7):2406-12. |
| Brown DR; Fowell DJ; Corry DB; Wynn TA; Moskowitz NH; Cheever AW; Locksley RM; Reiner SL. "Beta 2-microglobulin-dependent NK1.1+ T cells are not essential for T helper cell 2 immune responses." The Journal of experimental medicine. 1996; 184(4):1295-304. |
| Saoudi A; Seddon B; Fowell D; Mason D. "The thymus contains a high frequency of cells that prevent autoimmune diabetes on transfer into prediabetic recipients." The Journal of experimental medicine. 1996; 184(6):2393-8. |
| Saoudi A; Seddon B; Heath V; Fowell D; Mason D. "The physiological role of regulatory T cells in the prevention of autoimmunity: the function of the thymus in the generation of the regulatory T cell subset." Immunological reviews. 1996; 149():195-216. |
| Locksley RM; Wakil AE; Corry DB; Pingel S; Bix M; Fowell DJ. "The development of effector T cell subsets in murine Leishmania major infection." Ciba Foundation symposium. 1995; 195():110-7; discussion 117-22. |
| Fowell D; Powrie F; Saoudi A; Seddon B; Heath V; Mason D. "The role of subsets of CD4+ T cells in autoimmunity." Ciba Foundation symposium. 1995; 195():173-82; discussion 182-8. |
| Fowell DJ; Wakil AE; Locksley RM. "Interleukin-12 in murine leishmaniasis--match, flame or fuel?" Research in immunology. 1995; 146(7-8):566-75. |
| Cyster JG; Fowell D; Barclay AN. "Antigenic determinants encoded by alternatively spliced exons of CD45 are determined by the polypeptide but influenced by glycosylation." International immunology. 1994; 6(12):1875-81. |
| Fowell D; Mason D. "Evidence that the T cell repertoire of normal rats contains cells with the potential to cause diabetes. Characterization of the CD4+ T cell subset that inhibits this autoimmune potential." The Journal of experimental medicine. 1993; 177(3):627-36. |
| Mason D; Fowell D. "T-cell subsets in autoimmunity." Current opinion in immunology. 1992; 4(6):728-32. |
| Fowell D; McKnight AJ; Powrie F; Dyke R; Mason D. "Subsets of CD4+ T cells and their roles in the induction and prevention of autoimmunity." Immunological reviews. 1991; 123():37-64. |
| Powrie F; Fowell D; McKnight AJ; Mason D. "Lineage relationships and functions of CD4+ T-cell subsets in the rat." Research in immunology. 1991; 142(1):54-8. |
