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Showing 73 journal articles currently available.
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Klein I; Crispe IN. "Complete differentiation of CD8+ T cells activated locally within the transplanted liver." The Journal of experimental medicine. 2006; 203(2):437-47.
Epub 2006 Feb 13.
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Polakos NK; Cornejo JC; Murray DA; Wright KO; Treanor JJ; Crispe IN; Topham DJ; Pierce RH. "Kupffer cell-dependent hepatitis occurs during influenza infection." The American journal of pathology. 2006; 168(4):1169-78; quiz 1404-5.
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Wuensch SA; Pierce RH; Crispe IN. "Local intrahepatic CD8+ T cell activation by a non-self-antigen results in full functional differentiation." Journal of immunology (Baltimore, Md. : 1950). 2006; 177(3):1689-97.
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Crispe IN; Giannandrea M; Klein I; John B; Sampson B; Wuensch S. "Cellular and molecular mechanisms of liver tolerance." Immunological reviews. 2006; 213():101-18.
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John B; Crispe IN. "TLR-4 regulates CD8+ T cell trapping in the liver." Journal of immunology (Baltimore, Md. : 1950). 2005; 175(3):1643-50.
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Jin YH; Crispe IN; Park S. "Expression of hepatitis C virus core protein in hepatocytes does not modulate proliferation or apoptosis of CD8+ T cells." Yonsei medical journal. 2005; 46(6):827-34.
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Laouar Y; Crispe IN; Flavell RA. "Overexpression of IL-7R alpha provides a competitive advantage during early T-cell development." Blood. 2004; 103(6):1985-94.
Epub 2003 Oct 30.
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John B; Crispe IN. "Passive and active mechanisms trap activated CD8+ T cells in the liver." Journal of immunology (Baltimore, Md. : 1950). 2004; 172(9):5222-9.
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Cao Q; Xia Y; Azadniv M; Crispe IN. "The E2F-1 transcription factor promotes caspase-8 and bid expression, and enhances Fas signaling in T cells." Journal of immunology (Baltimore, Md. : 1950). 2004; 173(2):1111-7.
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Murray DA; Crispe IN. "TNF-alpha controls intrahepatic T cell apoptosis and peripheral T cell numbers." Journal of immunology (Baltimore, Md. : 1950). 2004; 173(4):2402-9.
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Crispe IN. "Hepatic T cells and liver tolerance." Nature reviews. Immunology. 2003; 3(1):51-62.
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Huleatt JW; Cresswell J; Bottomly K; Crispe IN. "P27kip1 regulates the cell cycle arrest and survival of activated T lymphocytes in response to interleukin-2 withdrawal." Immunology. 2003; 108(4):493-501.
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Topham DJ; Crispe IN. "Contrasting urban and rural lifestyles of memory CD8+ T cells." Immunity. 2003; 18(5):584-6.
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Park S; Murray D; John B; Crispe IN. "Biology and significance of T-cell apoptosis in the liver." Immunology and cell biology. 2002; 80(1):74-83.
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Klugewitz K; Blumenthal-Barby F; Schrage A; Knolle PA; Hamann A; Crispe IN. "Immunomodulatory effects of the liver: deletion of activated CD4+ effector cells and suppression of IFN-gamma-producing cells after intravenous protein immunization." Journal of immunology (Baltimore, Md. : 1950). 2002; 169(5):2407-13.
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Bae Y; Crispe IN. "Differential regulation of cell cycle-related proteins by CD95 engagement in thymocytes and T cell leukemic cell line, Jurkat." Journal of cellular biochemistry. 2001; 80(3):328-38.
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Dao T; Exley M; Mehal WZ; Tahir SM; Snapper S; Taniguchi M; Balk SP; Crispe IN. "Involvement of CD1 in peripheral deletion of T lymphocytes is independent of NK T cells." Journal of immunology (Baltimore, Md. : 1950). 2001; 166(5):3090-7.
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Mehal WZ; Azzaroli F; Crispe IN. "Immunology of the healthy liver: old questions and new insights." Gastroenterology. 2001; 120(1):250-60.
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Doyle IS; Hollmann CA; Crispe IN; Owens T. "Specific blockade by CD54 and MHC II of CD40-mediated signaling for B cell proliferation and survival." Experimental cell research. 2001; 265(2):312-8.
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Mehal WZ; Azzaroli F; Crispe IN. "Antigen presentation by liver cells controls intrahepatic T cell trapping, whereas bone marrow-derived cells preferentially promote intrahepatic T cell apoptosis." Journal of immunology (Baltimore, Md. : 1950). 2001; 167(2):667-73.
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Bi B; Littlewood NK; Crispe IN. "Cleavage of E2F-1-regulating proteins and activation of E2F-1 during CD95-induced death of thymocytes." Immunology. 2001; 104(1):37-42.
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Crispe IN. "Do natural T cells promote liver regeneration?" Hepatology (Baltimore, Md.). 2000; 31(4):1022-4.
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Hingorani R; Bi B; Dao T; Bae Y; Matsuzawa A; Crispe IN. "CD95/Fas signaling in T lymphocytes induces the cell cycle control protein p21cip-1/WAF-1, which promotes apoptosis." Journal of immunology (Baltimore, Md. : 1950). 2000; 164(8):4032-6.
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Crispe IN; Dao T; Klugewitz K; Mehal WZ; Metz DP. "The liver as a site of T-cell apoptosis: graveyard, or killing field?" Immunological reviews. 2000; 174():47-62.
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Laouar Y; Crispe IN. "Functional flexibility in T cells: independent regulation of CD4+ T cell proliferation and effector function in vivo." Immunity. 2000; 13(3):291-301.
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Mehal WZ; Juedes AE; Crispe IN. "Selective retention of activated CD8+ T cells by the normal liver." Journal of immunology (Baltimore, Md. : 1950). 1999; 163(6):3202-10.
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Crispe IN. "Death and destruction of activated T lymphocytes." Immunologic research. 1999; 19(2-3):143-57.
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O'Farrelly C; Crispe IN. "Prometheus through the looking glass: reflections on the hepatic immune system." Immunology today. 1999; 20(9):394-8.
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Mehal WZ; Crispe IN. "TCR ligation on CD8+ T cells creates double-negative cells in vivo." Journal of immunology (Baltimore, Md. : 1950). 1998; 161(4):1686-93.
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Dao T; Mehal WZ; Crispe IN. "IL-18 augments perforin-dependent cytotoxicity of liver NK-T cells." Journal of immunology (Baltimore, Md. : 1950). 1998; 161(5):2217-22.
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Zheng TS; Schlosser SF; Dao T; Hingorani R; Crispe IN; Boyer JL; Flavell RA. "Caspase-3 controls both cytoplasmic and nuclear events associated with Fas-mediated apoptosis in vivo." Proceedings of the National Academy of Sciences of the United States
of America. 1998; 95(23):13618-23.
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Wack A; Corbella P; Harker N; Crispe IN; Kioussis D. "Multiple sites of post-activation CD8+ T cell disposal." European journal of immunology. 1997; 27(3):577-83.
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Dao T; Huleatt JW; Hingorani R; Crispe IN. "Specific resistance of T cells to CD95-induced apoptosis during S phase of the cell cycle." Journal of immunology (Baltimore, Md. : 1950). 1997; 159(9):4261-7.
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Peng SL; Madaio MP; Hughes DP; Crispe IN; Owen MJ; Wen L; Hayday AC; Craft J. "Murine lupus in the absence of alpha beta T cells." Journal of immunology (Baltimore, Md. : 1950). 1996; 156(10):4041-9.
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Livák F; Welsh SC; Guidos CJ; Crispe IN; Danska JS; Schatz DG. "Transient restoration of gene rearrangement at multiple T cell receptor loci in gamma-irradiated scid mice." The Journal of experimental medicine. 1996; 184(2):419-28.
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Crispe IN. "Frequency of T-cell progenitors in nude mice." Developmental immunology. 1996; 4(4):257-61.
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Crispe IN; Mehal WZ. "Strange brew: T cells in the liver." Immunology today. 1996; 17(11):522-5.
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Hughes DP; Hayday A; Craft JE; Owen MJ; Crispe IN. "T cells with gamma/delta T cell receptors (TCR) of intestinal type are preferentially expanded in TCR-alpha-deficient lpr mice." The Journal of experimental medicine. 1995; 182(1):233-41.
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Alam SM; Crispe IN; Gascoigne NR. "Allelic exclusion of mouse T cell receptor alpha chains occurs at the time of thymocyte TCR up-regulation." Immunity. 1995; 3(4):449-58.
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Hughes DP; Crispe IN. "A naturally occurring soluble isoform of murine Fas generated by alternative splicing." The Journal of experimental medicine. 1995; 182(5):1395-401.
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Livak F; Petrie HT; Crispe IN; Schatz DG. "In-frame TCR delta gene rearrangements play a critical role in the alpha beta/gamma delta T cell lineage decision." Immunity. 1995; 2(6):617-27.
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Huang L; Sye K; Crispe IN. "Proliferation and apoptosis of B220+CD4-CD8-TCR alpha beta intermediate T cells in the liver of normal adult mice: implication for lpr pathogenesis." International immunology. 1994; 6(4):533-40.
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Crispe IN. "Fatal interactions: Fas-induced apoptosis of mature T cells." Immunity. 1994; 1(5):347-9.
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Huang L; Soldevila G; Leeker M; Flavell R; Crispe IN. "The liver eliminates T cells undergoing antigen-triggered apoptosis in vivo." Immunity. 1994; 1(9):741-9.
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Crispe IN. "CD4/CD8-negative T cells with alpha beta antigen receptors." Current opinion in immunology. 1994; 6(3):438-41.
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Crispe IN; Huang L. "Neonatal, moribund and undead T cells: the role of the liver in T cell development." Seminars in immunology. 1994; 6(1):39-41.
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Huang L; Crispe IN. "Superantigen-driven peripheral deletion of T cells. Apoptosis occurs in cells that have lost the alpha/beta T cell receptor." Journal of immunology (Baltimore, Md. : 1950). 1993; 151(4):1844-51.
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Petrie HT; Livak F; Schatz DG; Strasser A; Crispe IN; Shortman K. "Multiple rearrangements in T cell receptor alpha chain genes maximize the production of useful thymocytes." The Journal of experimental medicine. 1993; 178(2):615-22.
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Langmuir PB; Bridgett MM; Bothwell AL; Crispe IN. "Bone marrow abnormalities in the non-obese diabetic mouse." International immunology. 1993; 5(2):169-77.
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Smyth L; Howell M; Crispe IN. "Self-reactivity and the expression of memory markers vary independently in MRL-Mp+/+ and MRL-Mp-lpr/lpr mice." Developmental immunology. 1992; 2(4):309-18.
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Huang L; Crispe IN. "Distinctive selection mechanisms govern the T cell receptor repertoire of peripheral CD4-CD8- alpha/beta T cells." The Journal of experimental medicine. 1992; 176(3):699-706.
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Maloy KJ; Mowat AM; Zamoyska R; Crispe IN. "Phenotypic heterogeneity of intraepithelial T lymphocytes from mouse small intestine." Immunology. 1991; 72(4):555-62.
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Alterman LA; Crispe IN; Kinnon C. "Characterization of the murine heat-stable antigen: an hematolymphoid differentiation antigen defined by the J11d, M1/69 and B2A2 antibodies." European journal of immunology. 1990; 20(7):1597-602.
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Moore MW; Crispe IN; Bevan MJ. "Analysis of T cell receptor gamma chains from adult CD4- CD8- thymocytes." European journal of immunology. 1989; 19(8):1501-4.
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Husmann LA; Shimonkevitz RP; Crispe IN; Bevan MJ. "Thymocyte subpopulations during early fetal development in the BALB/c mouse." Journal of immunology (Baltimore, Md. : 1950). 1988; 141(3):736-40.
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Cardarelli PM; Crispe IN; Pierschbacher MD. "Preferential expression of fibronectin receptors on immature thymocytes." The Journal of cell biology. 1988; 106(6):2183-90.
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Crispe IN; Bevan MJ. "Expression and functional significance of the J11d marker on mouse thymocytes." Journal of immunology (Baltimore, Md. : 1950). 1987; 138(7):2013-8.
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Crispe IN; Shimonkevitz RP; Husmann LA; Kimura J; Allison JP. "Expression of T cell antigen receptor beta-chains on subsets of mouse thymocytes. Analysis by three-color flow cytometry." Journal of immunology (Baltimore, Md. : 1950). 1987; 139(11):3585-9.
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Shimonkevitz RP; Husmann LA; Bevan MJ; Crispe IN. "Transient expression of IL-2 receptor precedes the differentiation of immature thymocytes." Nature. 1987; 329(6135):157-9.
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Crispe IN; Moore MW; Husmann LA; Smith L; Bevan MJ; Shimonkevitz RP. "Differentiation potential of subsets of CD4-8- thymocytes." Nature. 1987; 329(6137):336-9.
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Crispe IN; Husmann LA; Bevan MJ. "T cell receptor expression and receptor-mediated induction of clonal growth in the developing mouse thymus. High surface beta-chain density is a requirement for functional maturity." European journal of immunology. 1986; 16(10):1283-8.
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Owens T; Crispe IN. "Suppressor T cells, distinct from "veto cells," are induced by alloantigen priming and mediate transferable suppression of cytotoxic T lymphocyte responses in vivo." Journal of immunology (Baltimore, Md. : 1950). 1985; 135(5):2984-9.
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Crispe IN; Owens T. "Suppression induction in vivo by a T helper clone?" European journal of immunology. 1985; 15(4):407-9.
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Crispe IN; Bevan MJ; Staerz UD. "Selective activation of Lyt 2+ precursor T cells by ligation of the antigen receptor." Nature. 1985; 317(6038):627-9.
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Gascoigne NR; Crispe IN. "Suppression of the cytotoxic T cell response to minor alloantigens in vivo. Linked recognition by suppressor T cells." European journal of immunology. 1984; 14(3):210-5.
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Crispe IN; Gascoigne NR; Owens T. "An allospecific murine T helper clone which can help both T and B cell responses in vitro and in vivo." Immunology. 1984; 52(1):55-65.
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Owens T; Czitrom AA; Gascoigne NR; Crispe IN; Ratcliffe MJ; Lai PK; Mitchison NA. "The presentation of cell surface alloantigens to T cells." Immunobiology. 1984; 168(3-5):189-201.
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Owens T; Liddell ME; Crispe IN. "Derivation from an alloreactive T-cell line of a clone which cross-reacts with a self H2-E-restricted minor alloantigen." Cellular immunology. 1984; 85(2):436-46.
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Gascoigne NR; Crispe IN. "Differential expression of the repertoire in in vitro and in vivo responses to minor alloantigens." Immunogenetics. 1984; 19(6):511-7.
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Crispe IN; LaThangue NB. "Cancer is not due to the expression of introns." Journal of theoretical biology. 1984; 107(2):339-40.
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Crispe IN; Gascoigne NR. "Computer-assisted analysis of in vivo cytotoxic T cell responses." Journal of immunological methods. 1983; 64(1-2):91-8.
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Weiss L; Holmes J; Crispe IN. "Effects of prior injection of Walker cancer cells in the rat on the lung-retention pattern of a second dose." British journal of cancer. 1979; 40(3):483-8.
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Crispe IN. "The effect of vinblastine, colchicine and hexylene glycol on migration of human monocytes." Experimental cell research. 1976; 100(2):443-7.
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